Genetic Heavy Metal Toxicity PDF Download
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Author: Tara Lang Chapman
Publisher: iUniverse
ISBN: 059548056X
Category : Health & Fitness
Languages : en
Pages : 152
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Book Description
Book claims that heavy metal poisoning is the cause of many neurological disorders, and is passed on from one generation to the next through epigenetics.
Author: Tara Lang Chapman
Publisher: iUniverse
ISBN: 059548056X
Category : Health & Fitness
Languages : en
Pages : 152
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Book Description
Book claims that heavy metal poisoning is the cause of many neurological disorders, and is passed on from one generation to the next through epigenetics.
Author: Ozgur Karcioglu
Publisher: BoD – Books on Demand
ISBN: 1838807853
Category : Medical
Languages : en
Pages : 130
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Book Description
Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.
Author: Jerome O. Nriagu
Publisher: MIT Press
ISBN: 0262552485
Category : Medical
Languages : en
Pages : 501
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Book Description
Experts explore the influence of trace metals on the pathogenesis of infectious diseases. Many parts of the world in which common infectious diseases are endemic also have the highest prevalence of trace metal deficiencies or rising rates of trace metal pollution. Infectious diseases can increase human susceptibility to adverse effects of metal exposure (at suboptimal or toxic levels), and metal excess or deficiency can increase the incidence or severity of infectious diseases. The co-clustering of major infectious diseases with trace metal deficiency or toxicity has created a complex web of interactions with serious but poorly understood health repercussions, yet has been largely overlooked in animal and human studies. This book focuses on the distribution, trafficking, fate, and effects of trace metals in biological systems. Its goal is to enhance our understanding of the relationships between homeostatic mechanisms of trace metals and the pathogenesis of infectious diseases. Drawing on expertise from a range of fields, the book offers a comprehensive review of current knowledge on vertebrate metal-withholding mechanisms and the strategies employed by different microbes to avoid starvation (or poisoning). Chapters summarize current, state-of-the-art techniques for investigating pathogen-metal interactions and highlight open question to guide future research. The book makes clear that improving knowledge in this area will be instrumental to the development of novel therapeutic measures against infectious diseases. Contributors M. Leigh Ackland, Vahid Fa Andisi, Angele L. Arrieta, Michael A. Bachman, J. Sabine Becker, Robert E. Black, Julia Bornhorst, Sascha Brunke, Joseph A. Caruso, Jennifer S. Cavet, Anson C. K. Chan, Christopher H. Contag, Heran Darwin, George V. Dedoussis, Rodney R. Dietert, Victor J. DiRita, Carol A. Fierke, Tamara Garcia-Barrera, David P. Giedroc, Peter-Leon Hagedoorn, James A. Imlay, Marek J. Kobylarz, Joseph Lemire, Wenwen Liu, Slade A. Loutet, Wolfgang Maret, Andreas Matusch, Trevor F. Moraes, Michael E. P. Murphy, Maribel Navarro, Jerome O. Nriagu, Ana-Maria Oros-Peusquens, Elisabeth G. Pacyna, Jozef M. Pacyna, Robert D. Perry, John M. Pettifor, Stephanie Pfaffen, Dieter Rehder, Lothar Rink, Anthony B. Schryvers, Ellen K. Silbergeld, Eric P. Skaar, Miguel C. P. Soares, Kyrre Sundseth, Dennis J. Thiele, Richard B. Thompson, Meghan M. Verstraete, Gonzalo Visbal, Fudi Wang, Mian Wang, Thomas J. Webster, Jeffrey N. Weiser, Günter Weiss, Inga Wessels, Bin Ye, Judith T. Zelikoff, Lihong Zhang
Author: Mohammad Anwar Hossain
Publisher: John Wiley & Sons
ISBN: 1119906466
Category : Science
Languages : en
Pages : 645
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Book Description
Comprehensive resource detailing the molecular mechanisms underlying heavy metal toxicity and tolerance in plants Heavy Metal Toxicity and Tolerance in Plants provides a comprehensive overview of the physiological, biochemical, and molecular basis of heavy metal tolerance and functional omics that allow for a deeper understanding of using heavy metal tolerance for deliberate manipulation of plants. Through the authors’ unique approach, the text enables researchers to develop strategies to enhance metal toxicity and deficiency tolerance as well as crop productivity under stressful conditions, in order to better utilize natural resources to ensure future food security. The text presents the basic knowledge of plant heavy metal/metalloid tolerance using modern approaches, including omics, nanotechnology, and genetic manipulation, and covers molecular breeding, genetic engineering, and approaches for high yield and quality under metal toxicity or deficiency stress conditions. With a collection of 26 chapters contributed by the leading experts in the fields surrounding heavy metal and metalloids toxicity and tolerance in crop plants, Heavy Metal Toxicity and Tolerance in Plants includes further information on: Advanced techniques in omics research in relation to heavy metals/metalloids toxicity and tolerance Heavy metals/metalloids in food crops and their implications for human health Molecular mechanisms of heavy metals/metalloids toxicity and tolerance in plants Molecular breeding approaches for reducing heavy metals load in the edible plant parts Hormonal regulation of heavy metals toxicity and tolerance Applications of nanotechnology for improving heavy metals stress tolerance Genetic engineering for heavy metals/metalloids stress tolerance in plants With comprehensive coverage of the subject, Heavy Metal Toxicity and Tolerance in Plants is an essential reference for researchers working on developing plants tolerant to metals/metalloids stress and effective strategies for reducing the risk of health hazards.
Author: Gaspar Banfalvi
Publisher: Springer Science & Business Media
ISBN: 9400704283
Category : Medical
Languages : en
Pages : 348
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Book Description
The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.
Author: Luigi De Bellis
Publisher: Mdpi AG
ISBN: 9783039366330
Category : Science
Languages : en
Pages : 364
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Book Description
In recent years, heavy metals have been widely used in agricultural, chemical, domestic, and technological applications, causing environmental and soil contaminations. Heavy metals enter the plant system through soil or via the atmosphere, and can accumulate, affecting physiological processes, plant growth, yield, and human health if heavy metals are stored in edible tissues. Understanding the regulation mechanisms of plant heavy metals accumulation and partitioning is important to improve the safety of the food chain. In this Special Issue book, a total of 19 articles were included; four reviews covering phytoremediation, manganese phytotoxicity in plants, the effect of cadmium on plant development, the genetic characteristics of Cd accumulation, and the research status of genes and QTLs in rice, respectively, as well as fifteen original research articles, mainly regarding the impact of cadmium on plants. Cadmium was therefore the predominant topic of this Special Issue, increasing the attention of the research community on the negative impacts determined by cadmium or cadmium associated with other heavy metals. The articles have highlighted a great genetic variability, suggesting different possibilities for accumulation, translocation and the reduction or control of heavy metal toxicity in plants.
Author: Lars Friberg
Publisher: Elsevier Science & Technology
ISBN:
Category : Medical
Languages : en
Pages : 758
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Book Description
Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.
Author: Dharmendra K. Gupta
Publisher: Springer Science & Business Media
ISBN: 3642384692
Category : Science
Languages : en
Pages : 245
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Book Description
Plants possess a range of potential cellular mechanisms that may be involved in the detoxification of heavy metals and thus tolerance to metal stress. Metal toxicity causes multiple direct and indirect effects in plants that concern practically all physiological functions. The main purpose of this book is to present comprehensive and concise information on recent advances in the field of metal transport and how genetic diversity affects heavy metal transport in plants. Other key futures of the book are related to metal toxicity and detoxification mechanisms, biochemical tools for HM remediation processes, molecular mechanisms for HM detoxification, how metallomics and metalloproteomics are affected by heavy metal stress in plants, and the role of ROS metabolism in the alleviation of heavy metals. Some chapters also focus on recent developments in the field of phytoremediation. Overall the book presents in-depth information and the most essential advances in the field of heavy metal toxicity in plants in recent years.
Author: Dharmendra K. Gupta
Publisher: Springer Science & Business Media
ISBN: 3642220819
Category : Science
Languages : en
Pages : 268
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Book Description
Heavy metal accumulation in soil and water from natural sources or anthropogenic activities have produced severe environmental contamination in some parts of the world due to the persistence of metals in the environment by their accumulation throughout the food chain. The purpose of this book is to present the most recent advances in this field, mainly concerning the uptake and translocation of heavy metals in plants, mechanisms of toxicity, perception of metal and regulation of cell response under metal stress. Another key feature of this book is related to the studies on signaling and remediation processes in recent years, which have taken advantage of recent technological advances including "omic" approaches. In recent years transcriptomic, proteomic and metabolomic studies have become very important tools for analyzing both the dynamics of changes in gene expression and the profiles of protein and metabolites under heavy metal stress. This information is also very useful for plotting the complex signaling and metabolic network induced by heavy metals, in which hormones and reactive oxygen species (ROS) also play an important role. Understanding the mechanism involved in sequestration and hyperaccumulation is very important to developing new strategies of phytoremediation, which are reviewed in several chapters of this book. The information included yields very stimulating insights into the mechanism involved in the regulation of plant responses to heavy metals, which in turn improve our knowledge of cell regulation under metal stress and the use of plants for phytoremediation.
Author: Mathieu Cellier
Publisher: Springer Science & Business Media
ISBN: 9780306478413
Category : Science
Languages : en
Pages : 226
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Book Description
This book is the first comprehensive volume on the "Nramp family", highlighting the physiological importance of Nramp proteins as metal transporters. The molecular knowledge of these membrane proteins is presented from an evolutionary perspective, considering Nramp cellular function and mechanism of transport in key model organisms. The pathological significance of Nramp genetic polymorphism is discussed with emphasis on metal homeostasis and microbial infection. The chapters were contributed by leading investigators, providing a timely state of the art book in this rapidly growing field. The Nramp Family will be useful to a broad community of scientists interested in metal transport and molecular biology. It will be of interest to the research audience in the broad fields of metal ions and molecular medicine.
