Genetic Approaches to Coronary Heart Disease and Hypertension

Genetic Approaches to Coronary Heart Disease and Hypertension PDF Author: Kare Berg
Publisher: Springer Science & Business Media
ISBN: 3642768911
Category : Medical
Languages : en
Pages : 256

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Book Description
Cardiovascular diseases are the principal cause of mortality in many developed countries and are increasing in importance in developing countries where communicable diseases are being brought under control. It is estimated that coronary heart disease (CRD) and cerebrovascular diseases are responsible for between 40-50% of all deaths. Righ blood pressure is common in all industrialized societies and contributes importantly to CRD. It is well known that genetic factors play an important role in the etiology and pathogenes es of cardiovascular diseases and contribute to an individual's susceptibility or resistance to the disease. The application of modern genetic techniques has resulted in the identification of polymorphie markers that are involved in the normal regulation and function of the cardiovascular system. Many of these may contribute to the individual differences in the risk for CRD and hypertension. It is now known that several risk factors or protective factors with respect to cardiovascular diseases are strongly influenced by genes, and it is now possible to identify individual genes contributing to cardiovascular risk. A large bank of genetic knowledge relevant to CRD and hypertension has become available during the past years. As a result, it is now believed that CRD, for example, could be a good model for a feasibility study to determine a way by which preventive measures can be applied.

Genetic Approaches to Coronary Heart Disease and Hypertension

Genetic Approaches to Coronary Heart Disease and Hypertension PDF Author: Kare Berg
Publisher: Springer Science & Business Media
ISBN: 3642768911
Category : Medical
Languages : en
Pages : 256

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Book Description
Cardiovascular diseases are the principal cause of mortality in many developed countries and are increasing in importance in developing countries where communicable diseases are being brought under control. It is estimated that coronary heart disease (CRD) and cerebrovascular diseases are responsible for between 40-50% of all deaths. Righ blood pressure is common in all industrialized societies and contributes importantly to CRD. It is well known that genetic factors play an important role in the etiology and pathogenes es of cardiovascular diseases and contribute to an individual's susceptibility or resistance to the disease. The application of modern genetic techniques has resulted in the identification of polymorphie markers that are involved in the normal regulation and function of the cardiovascular system. Many of these may contribute to the individual differences in the risk for CRD and hypertension. It is now known that several risk factors or protective factors with respect to cardiovascular diseases are strongly influenced by genes, and it is now possible to identify individual genes contributing to cardiovascular risk. A large bank of genetic knowledge relevant to CRD and hypertension has become available during the past years. As a result, it is now believed that CRD, for example, could be a good model for a feasibility study to determine a way by which preventive measures can be applied.

Genetic Approaches of Coronary Heart Disease and Hypertension

Genetic Approaches of Coronary Heart Disease and Hypertension PDF Author: Kare Berg
Publisher: Springer Verlag
ISBN: 9780387544762
Category : Medical
Languages : en
Pages : 159

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Book Description


Beat the Heart Attack Gene

Beat the Heart Attack Gene PDF Author: Bradley Bale
Publisher: Turner Publishing Company
ISBN: 1630260568
Category : Health & Fitness
Languages : en
Pages : 232

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Book Description
A revolutionary, personalized guide to preventing heart disease—America’s #1 killer Heart disease is the #1 cause of death in America. It affects 81 million Americans and is the culprit in one of every two deaths in the United States. Most people think that they are not at risk of a heart attack if they control their cholesterol and blood pressure, but they aren’t aware of other major risk factors. The good news is that with the right information and strategies, heart attacks are preventable—even if heart disease runs in the family. In Beat the Heart Attack Gene, world-renowned cardiovascular specialists Bradley Bale, MD and Amy Doneen, ARNP, present a new model for understanding and preventing heart disease. They explain the three different genetic types of cholesterol profiles and tailor treatments for each type, using their cutting-edge Bale/Doneen Method, a comprehensive, evidence-based medical treatment plan that detects cardiovascular disease (CVD) at early stages and stabilizes it with individualized medical and lifestyle therapy. Beat the Heart Attack Gene includes easy quizzes and self-tests that show how to determine cholesterol genotype as well as advice for how to apply that knowledge through and individualized lifestyle advice. For heart attack and stroke survivors, the Bale/Doneen Method also helps prevent recurrences by identifying and treating what's triggering the patient's disease—a crucial step that many cardiologists neglect. With their proven method utilized by healthcare professionals worldwide, Bale and Doneen empower readers by alerting them to potential health threats, and then offer personalized strategies so they can live healthy, active lives without fear of heart attack or stroke. Specifically, Beat the Heart Attack Gene addresses: *The hidden cause of most heart attacks *Early prevention methods *The dangerous cholesterol most doctors don’t check *Major red flags for heart attack and stroke risk, including gum disease *The genes that increase cardiovascular risk as much as smoking *The best and worst supplements and foods for your heart *10 surprising ways to prevent heart attacks

Cardiovascular Genetics and Genomics for the Cardiologist

Cardiovascular Genetics and Genomics for the Cardiologist PDF Author: Victor J. Dzau, MD
Publisher: John Wiley & Sons
ISBN: 0470765941
Category : Medical
Languages : en
Pages : 328

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Book Description
Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way cardiovascular medicine is practiced • what material has immediate relevance to the practicing clinician • how to incorporate genetics and genomics in your practice to ensure up-to-date patient care The book opens with introductory chapters, then discusses: • cardiovascular single gene disorders • cardiovascular polygenic disorders • therapies and applications Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.

Genetics of coronary heart disease

Genetics of coronary heart disease PDF Author:
Publisher:
ISBN:
Category : Coronary heart disease
Languages : en
Pages : 240

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Book Description


Molecular Genetics & Gene Therapy of Cardiovascular Diseases

Molecular Genetics & Gene Therapy of Cardiovascular Diseases PDF Author: S. C. Mockrin
Publisher: CRC Press
ISBN: 1482273241
Category : Medical
Languages : en
Pages : 616

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Book Description
Provides detailed discussions of the most recent developments in gene mapping and manipulation to improve the diagnosis, detection, prevention, and treatment of various cardiovascular diseases--including hypertension, arrhythmias, inherited cariomyopathies, hyperlipidemia, aortic aneurysms, Marfan syndrome, and myocardial infarction. Written by nea

Genetic Approaches to Noncommunicable Diseases

Genetic Approaches to Noncommunicable Diseases PDF Author: Kare Berg
Publisher: Springer Science & Business Media
ISBN: 3642610285
Category : Medical
Languages : en
Pages : 232

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Book Description
In recent years, the progress made in the prevention of mortality and morbidity caused by communicable diseases and malnutrition has changed the disease spectrum in both developed and, particularly developing countries. As a result, noncommunicable diseases, includ ing genetic disorders, have achieved considerable importance in public health. Furthermore, it is now evident that inherited predisposition is important in a number of common diseases that occur in later life, such as atherosclerosis, coronary heart disease, hypertension, diabetes mellitus, and in some rheumatic, oncological, and mental illnesses that appear at an early stage and develop into severe handicaps in predisposed people. Rapid advances in gene mapping concerned with international human genome research make it almost certain that the use of new genetic knowledge will dramatically increase the requirement for genetic approaches in the control of a wide spectrum of diseases, and will provide possibilities for their prevention and treatment in the form of changes in lifestyle, diet modification, periodic check-ups, or the administration of gene therapy. It appears that one of the main problems in delivering genetics services is the difficulty involved in informing the health profession and the community of the real sig nificance of genetic problems. There is, therefore, a need for international collaboration in improving genetic health education at all levels and in improving health through genetic approaches.

Cardiovascular Genomics

Cardiovascular Genomics PDF Author: Mohan K. Raizada
Publisher: Springer Science & Business Media
ISBN: 1592598838
Category : Medical
Languages : en
Pages : 367

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Book Description
Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

Coronary Artery Disease

Coronary Artery Disease PDF Author: Gregory W. Barsness
Publisher: Springer Science & Business Media
ISBN: 184628712X
Category : Medical
Languages : en
Pages : 196

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Book Description
A book directed towards individuals with an interest in the clinical treatment of patients with unrevascularizable angina. It explores the treatment options in the setting of a sound scientific background and provides guidance and predictions for future directions in this rapidly developing field. It is the only textbook of its kind and fulfils an unmet need for practicing internal medicine, family practice and cardiovascular clinicians. It also provides a reliable reference for clinical and basic researchers interested in this topic.

Molecular Genetics of Hypertension

Molecular Genetics of Hypertension PDF Author:
Publisher: Academic Press
ISBN: 9780122204302
Category : Science
Languages : en
Pages : 0

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Book Description
This is a rapidly expanding research area, with most current publications existing as journal articles, or as single chapters in larger volumes. This will be one of the first books to bring all this information together into a comprehensive review volume, aimed at both researchers and clinicians. Hypertension is a condition in humans which is characterized by persistently high arterial blood pressure (over 140/90 mm Hg). Affected individuals are at risk from heart disease, stroke and kidney failure. This important disease affects a huge number of people worldwide, and therefore the study of the disease is of vital clinical importance. Hypertension is a genetically determined disease, with many other contributing factors. Research has expanded rapidly in this area, particularly over the last decade, and there are continuing advances in our understanding of the disease.