Generalized Quantitative Transmission Disequilibrium Test for Analyzing Genetic Main Effects and Epistasis

Generalized Quantitative Transmission Disequilibrium Test for Analyzing Genetic Main Effects and Epistasis PDF Author: Jingky Pamesa Lozano
Publisher:
ISBN: 9783869555829
Category :
Languages : en
Pages : 184

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Book Description

Generalized Quantitative Transmission Disequilibrium Test for Analyzing Genetic Main Effects and Epistasis

Generalized Quantitative Transmission Disequilibrium Test for Analyzing Genetic Main Effects and Epistasis PDF Author: Jingky Pamesa Lozano
Publisher:
ISBN: 9783869555829
Category :
Languages : en
Pages : 184

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Book Description


Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1026

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Book Description


Pharmacogenetics and Individualized Therapy

Pharmacogenetics and Individualized Therapy PDF Author: Anke-Hilse Maitland-van der Zee
Publisher: John Wiley & Sons
ISBN: 1118116461
Category : Medical
Languages : en
Pages : 502

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Book Description
This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific disease areas, including cardiovascular, psychiatry, cancer, asthma/COPD, adverse drug reactions, transplantation, inflammatory bowel disease, and pain medication. Clinical practice and ethical issues make up the third section, with the fourth devoted to technologies like genotyping, genomics, and proteomics. In the fifth part, chapters discuss the impact of key regulatory issues on the pharmaceutical industry.

The Fundamentals of Modern Statistical Genetics

The Fundamentals of Modern Statistical Genetics PDF Author: Nan M. Laird
Publisher: Springer Science & Business Media
ISBN: 1441973389
Category : Medical
Languages : en
Pages : 226

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Book Description
This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.

Genetics and Analysis of Quantitative Traits

Genetics and Analysis of Quantitative Traits PDF Author: Michael Lynch
Publisher: Sinauer Associates Incorporated
ISBN: 9780878934812
Category : Science
Languages : en
Pages : 980

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Book Description
Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Linear Models

Linear Models PDF Author: Shayle R. Searle
Publisher: John Wiley & Sons
ISBN: 0471184993
Category : Mathematics
Languages : en
Pages : 565

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Book Description
This 1971 classic on linear models is once again available--as a Wiley Classics Library Edition. It features material that can be understood by any statistician who understands matrix algebra and basic statistical methods.

Theoretical Aspects of Pedigree Analysis

Theoretical Aspects of Pedigree Analysis PDF Author: Emil Ginsburg
Publisher: RAMOT-TEL AVIV UNIVERSITY, ISRAEL
ISBN: 9652744247
Category : Biometric identification
Languages : en
Pages : 94

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Book Description


Nature Encyclopedia of the Human Genome: Mitochondrial heteroplasmy and disease - Relatives-based test for linkage disequilibrium: the transmission

Nature Encyclopedia of the Human Genome: Mitochondrial heteroplasmy and disease - Relatives-based test for linkage disequilibrium: the transmission PDF Author: David Neil Cooper
Publisher:
ISBN:
Category : Genetics
Languages : en
Pages : 1058

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Book Description


Mendel's Principles of Heredity

Mendel's Principles of Heredity PDF Author: William Bateson
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 238

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Book Description
Bateson named the science "genetics" in 1905-1906. This is the first textbook in English on the subject of genetics.

Bioinformatics for Geneticists

Bioinformatics for Geneticists PDF Author: Michael R. Barnes
Publisher: John Wiley & Sons
ISBN: 047086219X
Category : Science
Languages : en
Pages : 432

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Book Description
This timely book illustrates the value of bioinformatics, not simply as a set of tools but rather as a science increasingly essential to navigate and manage the host of information generated by genomics and the availability of completely sequenced genomes. Bioinformatics can be used at all stages of genetics research: to improve study design, to assist in candidate gene identification, to aid data interpretation and management and to shed light on the molecular pathology of disease-causing mutations. Written specifically for geneticists, this book explains the relevance of bioinformatics showing how it may be used to enhance genetic data mining and markedly improve genetic analysis.