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Author: Wolfgang G. Clauss
Publisher: Frontiers E-books
ISBN: 2889191141
Category :
Languages : en
Pages : 74
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Book Description
Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} Small gaseous molecules, such as nitric oxide (NO), carbon monoxide (CO) and hydrogen sulphide (H2S), are emerging as important regulators of various cellular functions. Especially ion channels and transporters have been demonstrated to represent prominent molecular targets for those gases and are thus key factors in gas-induced cell-signalling. This Research Topic will focus on the interaction of gaseous molecules with ion channels/transporters and will address the following questions: i) Which ion channels/transporters are regulated by gases? ii) How are ion channels/transporters mechanistically regulated by gases? iii) What are cellular and physiological processes, which are triggered by the interaction of gases with ion channels/transporters?
Author: Wolfgang G. Clauss
Publisher: Frontiers E-books
ISBN: 2889191141
Category :
Languages : en
Pages : 74
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Book Description
Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} Small gaseous molecules, such as nitric oxide (NO), carbon monoxide (CO) and hydrogen sulphide (H2S), are emerging as important regulators of various cellular functions. Especially ion channels and transporters have been demonstrated to represent prominent molecular targets for those gases and are thus key factors in gas-induced cell-signalling. This Research Topic will focus on the interaction of gaseous molecules with ion channels/transporters and will address the following questions: i) Which ion channels/transporters are regulated by gases? ii) How are ion channels/transporters mechanistically regulated by gases? iii) What are cellular and physiological processes, which are triggered by the interaction of gases with ion channels/transporters?
Author: Rui Wang
Publisher: Royal Society of Chemistry
ISBN: 1788014804
Category : Science
Languages : en
Pages : 316
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Book Description
Gasotransmitters are gas molecules produced endogenously in prokaryotic and eukaryotic cells for signalling purposes. This book provides, for the first time, a comprehensive description and systematic look at all gasotransmitters, established or proposed, since their detection in 2002. The content and scope covers the production, metabolism, and signalling roles of gasotransmitters. Conceptual advances, scientific discoveries and newly developed techniques described in this book influence our understanding of fundamental molecular and cellular events in biology and medicine. This book serves as the state-of-the-art book for undergraduate and graduate students as well as post-doctoral fellows in biomedical disciplines and toxicologists studying the toxic mechanisms of gasotransmitters in the environment. It will also be welcomed by researchers in university and research institutes, government agencies, pharmaceutical and medical instrument industry, and clinical practice.
Author: Po Sing Leung
Publisher: Springer Science & Business
ISBN: 9401787719
Category : Medical
Languages : en
Pages : 370
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Book Description
Gastrointestinal (GI) physiology is a fundamental subject that is indispensable not only for undergraduate but also for graduate courses. The audience include, but are not limited to, medical, pharmacy, nursing, human biology, Chinese medicine, and science students, as well as other health-related subject students. The overall objectives of this textbook are to present basic concepts and principles of GI physiology and, more importantly, to convey an understanding of how to apply this knowledge to abnormal GI physiology in the clinical context. As such, the basic knowledge of GI physiology and its application in the form of clinical case studies should be grasped, which are critical for professional examinations and bedside, as well as for general practice in the future. In this handbook, we aim to achieve these elements by covering the breadth of GI, pancreatic, hepatobiliary, and nutritional physiology. Moreover, we include relevant scenario-based clinical case in each chapter so as to evaluate whether the students can apply the basic GI they learn to the clinical setting.
Author: Tariq Aftab
Publisher: Springer Nature
ISBN: 3031430298
Category : Science
Languages : en
Pages : 331
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Book Description
Abiotic stressors, such as drought, extreme temperatures, heavy metals, or high salinity, are causing huge crop losses worldwide. These abiotic stressors are expected to become more extreme, less predictable, and more widespread in the near future. The harm of abiotic stresses includes the disruption of cellular redox homeostasis, reactive oxygen species (ROS) production, and oxidative stress in the plant. Plants have different mechanisms to fight stress, and these mechanisms are responsible for maintaining the required homeostasis in plants. Research on gasotransmitters is rapidly expanding and knowledge regarding the potential of gasotransmitters in biology and medicine is accumulating. Over the past few decades, the roles of these signaling molecules, especially NO and H2S, have been extensively studied for their application in plants. Recently, the emissions of endogenous gasotransmitters in plants have been widely studied and analyzed, thereby providing information to facilitate our understanding of new gasotransmitters signaling pathways. Given the multidimensional role of these signaling molecules, research over the past decades in mitigating abiotic stresses in plant biology and from an agriculture point of view, we intend to bring forth a comprehensive volume “Gasotransmitters Signaling in Plants under Challenging Environment". We are hopeful that this comprehensive volume will furnish the requisite of all those who are working or have an interest in the proposed topic
Author: Rui Wang
Publisher: Springer Science & Business Media
ISBN: 1592598064
Category : Medical
Languages : en
Pages : 372
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Book Description
Gasotransmitters-principally nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)-are endogenous signaling molecules that play a significant role in the biomedical, clinical, and health sciences, as well as in population health studies. In Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine, a panel of distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing their signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels. Included in the array of different mechanisms for the interaction of NO, CO, and H2S are channel phosphorylation, S-nitrosylation, carboxylation, sulfuration, and altered cellular redox status. The authors also offer guidance and suggestions for exploring and further characterizing other still unknown gasotransmitters. Authoritative and comprehensive, Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine offers clinical scientists and physicians not only a deeper understanding, but also a cutting-edge review, of the critically important field of gasotransmitter biology and medicine.
Author: Luit J. De Kok
Publisher: Springer Science & Business Media
ISBN: 9400744501
Category : Science
Languages : en
Pages : 276
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Book Description
This proceedings volume contains the invited and a selection of the contributed papers of the 8th International Workshop on Sulfur Metabolism in Higher Plants, which was held at Department of Forest and Ecosystem Science, University of Melbourne, Water Street, Creswick, Victoria 3363, Australia from November 22-27, 2010. Content of the volume shows that the understanding of sulfur metabolism in plants and the interaction of the environment are rapidly progressing. This volume covers various aspects of the regulation of sulfate uptake and assimilation in plants, from a cellular to a whole plant level, and additionally emphasizes interactions with other minerals. Moreover the significance of sulfur metabolism in biotic and abiotic stress responses, in food security and quality, and in relation to interactions with global change factors is discussed in detail.
Author: Donald W. Pfaff
Publisher: Springer
ISBN: 9781493934737
Category : Medical
Languages : en
Pages : 0
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Book Description
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Author: Nicholas Sperelakis
Publisher: Elsevier
ISBN: 0080574556
Category : Science
Languages : en
Pages : 1262
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Book Description
This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics
Author: Susan Standring
Publisher: Elsevier Health Sciences
ISBN: 0702077070
Category : Medical
Languages : en
Pages : 2602
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Book Description
Susan Standring, MBE, PhD, DSc, FKC, Hon FAS, Hon FRCS Trust Gray’s. Building on over 160 years of anatomical excellence In 1858, Drs Henry Gray and Henry Vandyke Carter created a book for their surgical colleagues that established an enduring standard among anatomical texts. After more than 160 years of continuous publication, Gray’s Anatomy remains the definitive, comprehensive reference on the subject, offering ready access to the information you need to ensure safe, effective practice. This 42nd edition has been meticulously revised and updated throughout, reflecting the very latest understanding of clinical anatomy from the world’s leading clinicians and biomedical scientists. The book’s acclaimed, lavish art programme and clear text has been further enhanced, while major advances in imaging techniques and the new insights they bring are fully captured in state of the art X-ray, CT, MR and ultrasonic images. The accompanying eBook version is richly enhanced with additional content and media, covering all the body regions, cell biology, development and embryogenesis – and now includes two new systems-orientated chapters. This combines to unlock a whole new level of related information and interactivity, in keeping with the spirit of innovation that has characterised Gray’s Anatomy since its inception. Each chapter has been edited by international leaders in their field, ensuring access to the very latest evidence-based information on topics Over 150 new radiology images, offering the very latest X-ray, multiplanar CT and MR perspectives, including state-of-the-art cinematic rendering The downloadable Expert Consult eBook version included with your (print) purchase allows you to easily search all of the text, figures, references and videos from the book on a variety of devices Electronic enhancements include additional text, tables, illustrations, labelled imaging and videos, as well as 21 specially commissioned ‘Commentaries’ on new and emerging topics related to anatomy Now featuring two extensive electronic chapters providing full coverage of the peripheral nervous system and the vascular and lymphatic systems. The result is a more complete, practical and engaging resource than ever before, which will prove invaluable to all clinicians who require an accurate, in-depth knowledge of anatomy.
Author: J. P. Mohr
Publisher: Elsevier Health Sciences
ISBN: 1437737803
Category : Medical
Languages : en
Pages : 1513
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Book Description
First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, Stroke: Pathophysiology, Diagnosis, and Management continues to provide the dependable, current answers you need to effectively combat the increasing incidence of this disease. Dr. J.P. Mohr, together with new associate editors Philip A. Wolf, James C. Grotta, Michael A. Moskowitz, Marc Mayberg, and Rüdiger von Kummer as well as a multitude of expert contributors from around the world, offer you updated and expanded coverage of mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more, equipping you to understand the latest scientific discoveries and make effective use of the newest approaches to diagnosis and treatment. Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke. Access the comprehensive, expert clinical guidance you need to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Make efficient and accurate diagnoses with the aid of abundant full-color CT images and pathology slides. Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more.
