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Author: Wataru Yasui
Publisher:
ISBN: 9783805598835
Category : Medical
Languages : en
Pages : 0
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Book Description
The highest rates of gastric cancer are observed in eastern Asia, South America and eastern Europe. More than half of all cases worldwide occur in eastern Asia. Distinguished experts in Asia have reviewed current topics and future perspectives for gastric cancer treatment in molecular pathology, tissue engineering, surgery and chemotherapy. Advances in diagnosis and treatment offer excellent long-term survival rates in the case of early cancer diagnosis, but the prognosis of advanced cancer still remains poor. A detailed understanding of molecular pathogenesis and the individual characteristics of gastric cancer and the development of new medical technologies and therapeutic agents help to provide personalized cancer care for patients of early and advanced cancer. For ongoing success, interactions and developments between bench and bedside as well as clinics and bench are crucial. This special issue is recommended for researchers, pathologists, surgeons, physicians and oncologists in the field of gastroenterology, who are interested in the current topics and future perspectives of molecular pathology, tissue engineering, surgery and chemotherapy of gastric cancer.
Author: Wataru Yasui
Publisher:
ISBN: 9783805598835
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
The highest rates of gastric cancer are observed in eastern Asia, South America and eastern Europe. More than half of all cases worldwide occur in eastern Asia. Distinguished experts in Asia have reviewed current topics and future perspectives for gastric cancer treatment in molecular pathology, tissue engineering, surgery and chemotherapy. Advances in diagnosis and treatment offer excellent long-term survival rates in the case of early cancer diagnosis, but the prognosis of advanced cancer still remains poor. A detailed understanding of molecular pathogenesis and the individual characteristics of gastric cancer and the development of new medical technologies and therapeutic agents help to provide personalized cancer care for patients of early and advanced cancer. For ongoing success, interactions and developments between bench and bedside as well as clinics and bench are crucial. This special issue is recommended for researchers, pathologists, surgeons, physicians and oncologists in the field of gastroenterology, who are interested in the current topics and future perspectives of molecular pathology, tissue engineering, surgery and chemotherapy of gastric cancer.
Author: W. Yasui
Publisher:
ISBN: 9783805598828
Category :
Languages : en
Pages : 0
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Book Description
The highest rates of gastric cancer are observed in eastern Asia, South America and eastern Europe. More than half of all cases worldwide occur in eastern Asia. Distinguished experts in Asia have reviewed current topics and future perspectives for gastric cancer treatment in molecular pathology, tissue engineering, surgery and chemotherapy. Advances in diagnosis and treatment offer excellent long-term survival rates in the case of early cancer diagnosis, but the prognosis of advanced cancer still remains poor. A detailed understanding of molecular pathogenesis and the individual characteristics of gastric cancer and the development of new medical technologies and therapeutic agents help to provide personalized cancer care for patients of early and advanced cancer. For ongoing success, interactions and developments between bench and bedside as well as clinics and bench are crucial. This special issue is recommended for researchers, pathologists, surgeons, physicians and oncologists in the field of gastroenterology, who are interested in the current topics and future perspectives of molecular pathology, tissue engineering, surgery and chemotherapy of gastric cancer.
Author: Destiny Arthur
Publisher:
ISBN: 9781632418760
Category : Medical
Languages : en
Pages : 244
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Book Description
Gastric cancer is the cancer, which develops in the lining of the stomach. Most stomach cancers are gastric carcinomas. Some of its early symptoms include upper abdominal pain, heartburn, nausea and loss of appetite. In its later stages, the cancer presents itself with yellowing of the skin and the whites of the eye, weight loss, vomiting and difficulty swallowing. More than 60% of gastric cancers are caused due to infection by Helicobacter pylori. If the cancer is detected and targeted early, it can be potentially cured. A gastroscopic exam involving the insertion of a fibre optic cable into the stomach, upper GI series and CT scanning of the abdomen can reveal gastric cancer. Treatments typically include a combination of radiation therapy, chemotherapy, targeted therapy and surgery. This book provides comprehensive insights into the current status and future perspectives of gastric cancer. It elucidates new techniques of assessment, diagnosis and management of gastric cancer in a multidisciplinary manner. Scientists and students actively engaged in oncology will find this book full of crucial and unexplored concepts.
Author: Vincenzo Canzonieri
Publisher: Springer
ISBN: 3030048616
Category : Medical
Languages : en
Pages : 259
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Book Description
Gastric cancer is one of the most common and potentially lethal gastrointestinal malignancy, but it is now at the forefront of modern oncology due to new discoveries. In recent years, the field of gastric cancer has been transformed by many notable developments in both the diagnostic area and the therapeutic strategies. The main aim of the text is to propose a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for oncologists, pathologists, surgeons and researchers with an interest in gastric cancer. The first chapters will review the interplay between pathogens and especially H. pylori, inflammation, genomic instability, and tumorigenesis. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspectives will be illustrated. Two specific chapters will deal with tissue and serum biomarkers with an important role in diagnosis as well as prognostic and predictive markers of response to specific therapy. A central section of the book will focus on treatment options available today for patients. Surgery is the cornerstone of treatment for gastric cancer; however, the prognosis of patients with locally advanced disease is still poor even after curative resection. Therefore, in order to improve the prognosis of patients, especially with advanced stage, a multimodal strategy is advisable and is thoroughly addressed in the appropriate section. With the advent of next-generation sequencing and new preclinical model technologies, the genomic landscape of gastric cancer has been delineated and molecular characterizations finalized to novel therapeutic targets of each molecular subtype have been identified. These advances are making it feasible to integrate clinical and phenotype-based diagnostic and therapeutic methods and are described in a dedicated section. The text will conclude with chapters focusing on the future direction of gastric cancer research in the precision medicine era: an in-depth analysis of non-coding RNAs and their role in gastric cancer, the impact of immunomodulation/immunotherapy and the perspectives of nano-medicine will be finally proposed to the audience. A brief review of the existing literature addressing the above mentioned topics will be present in each chapter. This text will serve as a useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.
Author: Yves Dittmar
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :
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Book Description
Future Perspectives in the Treatment of Incurable Gastric Cancer.
Author: U. Metzger
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170
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Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Author: Kenneth K. W. To
Publisher: Frontiers Media SA
ISBN: 2889748596
Category : Medical
Languages : en
Pages : 188
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Book Description
Author: Yves Dittmar
Publisher:
ISBN: 9789533074122
Category :
Languages : en
Pages :
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Book Description
Author: P. Malfertheiner
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805579233
Category : Medical
Languages : en
Pages : 110
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Book Description
The overall prognosis for patients with gastric cancer remains poor as tumors are often diagnosed at an advanced stage, despite new developments and technical advances in endoscopic diagnosis and therapy. This publication brings together leading experts in the fields of basic research and clinical management of gastric cancer, to share their expertise with the clinical community. State-of-the-art reviews discuss the pathogenesis of and the most important risk factors for the development of gastric cancer, potential benefits of chemoprevention and Helicobacter pylori eradication. Moreover, new diagnostic modalities and surgical therapy, including the potential benefits of neoadjuvant and adjuvant therapies, are presented. As most patients require palliative therapy because of locally advanced or metastasized cancers, several reviews are dedicated to advances in the chemotherapy of advanced gastric cancers and peritoneal metastasis. Finally, future approaches towards a molecular diagnosis and therapy are described. Those involved in the management of gastric cancer patients will find the information presented in this publication of utmost help and will benefit greatly for their daily routine.
Author: F. T. Bosman
Publisher: International Agency for Research on Cancer
ISBN:
Category : Medical
Languages : en
Pages : 424
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Book Description
"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].
