Basic Gas Chromatography-Mass Spectrometry

Basic Gas Chromatography-Mass Spectrometry PDF Author: F.W. Karasek
Publisher: Elsevier
ISBN: 0080929060
Category : Science
Languages : en
Pages : 210

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Book Description
The book begins by covering the basic principles of both gas chromatography (GC) and mass spectrometry (MS) to the extent necessary to understand and deal with the data generated in a GC-MS analysis. The focus then turns to the particular requirements created by a direct combination of these two techniques into a single instrumentation system. The data generated and their use are covered in detail. The role of the computer and its specific software receives special attention, especially in the matter of compound identification via mass spectral search techniques. GC-MS-computer instrumentation has reached such a plateau of excellence today that the present commercial systems will not be obsolete for a long time to come. Therefore, a detailed description of these systems is not only informative but is also pertinent to the subject matter of this book. Finally, representative applications and results obtained with GC-MS-computer techniques are presented and chosen in such a way as to permit extrapolation of specific applications to similar problems encountered by the reader. To aid the reader in mastering the subject matter and increase understanding, interpretation problems and suggested readings are included. The format is instructional, informative and application-oriented with material presented in such a way as to be useful to a broad spectrum of people.The book serves as a text in its own right.The software package Gas Chromatography-Mass Spectrometry: A Knowledge Base, by F.A. Settle, Jr. and M.A. Pleva provides rapid access to a wealth of current information in the GC-MS field. Its three diskettes (51/4 inch) allow the user three ways to access: the index mode, the tree mode and a keyword search mode. The package may be purchased separately and is available for the IBM-PC and compatibles.The software provides a valuable supplement to the book.

Basic Gas Chromatography-Mass Spectrometry

Basic Gas Chromatography-Mass Spectrometry PDF Author: F.W. Karasek
Publisher: Elsevier
ISBN: 0080929060
Category : Science
Languages : en
Pages : 210

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Book Description
The book begins by covering the basic principles of both gas chromatography (GC) and mass spectrometry (MS) to the extent necessary to understand and deal with the data generated in a GC-MS analysis. The focus then turns to the particular requirements created by a direct combination of these two techniques into a single instrumentation system. The data generated and their use are covered in detail. The role of the computer and its specific software receives special attention, especially in the matter of compound identification via mass spectral search techniques. GC-MS-computer instrumentation has reached such a plateau of excellence today that the present commercial systems will not be obsolete for a long time to come. Therefore, a detailed description of these systems is not only informative but is also pertinent to the subject matter of this book. Finally, representative applications and results obtained with GC-MS-computer techniques are presented and chosen in such a way as to permit extrapolation of specific applications to similar problems encountered by the reader. To aid the reader in mastering the subject matter and increase understanding, interpretation problems and suggested readings are included. The format is instructional, informative and application-oriented with material presented in such a way as to be useful to a broad spectrum of people.The book serves as a text in its own right.The software package Gas Chromatography-Mass Spectrometry: A Knowledge Base, by F.A. Settle, Jr. and M.A. Pleva provides rapid access to a wealth of current information in the GC-MS field. Its three diskettes (51/4 inch) allow the user three ways to access: the index mode, the tree mode and a keyword search mode. The package may be purchased separately and is available for the IBM-PC and compatibles.The software provides a valuable supplement to the book.

Fundamentals of Integrated GC-MS.

Fundamentals of Integrated GC-MS. PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description


CRC Handbook of Chromatography

CRC Handbook of Chromatography PDF Author: Ram N. Gupta
Publisher: CRC Press
ISBN: 0429945507
Category : Science
Languages : en
Pages : 408

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Book Description
These volumes provide a reference source of different gas chromatographic, liquid chromatographic, or thin-layer chromatographic techniques for the qualitative determination of various therapeutic agents, including antibiotics, vitamins and hormones, drugs of abuse in body fluids, dosage forms, or food stuffs. Over 5000 publications were reviewed to prepare tables of chromatographic data for 800 compounds, arranged alphabetically by generic drug name or by drug groups. A detailed summary of the extraction procedure described in each publication included in the table of a particular drug is also provided. This easy-to-read handbook is useful for selecting an appropriate chromatographic procedure for the determination of a given compound according to the available facilities.

Multidimensional Chromatography

Multidimensional Chromatography PDF Author: Hernan J. Cortes
Publisher: CRC Press
ISBN: 1000147436
Category : Science
Languages : en
Pages : 396

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Book Description
This book summarizes all the important aspects of multidimensional separations, providing information on gas, liquid and thin-layer chromatography, as well as the techniques and applications of supercritical fluid chromatography in the multidimensional mode.

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography PDF Author: Steven H.Y. Wong
Publisher: Routledge
ISBN: 1351408461
Category : Medical
Languages : en
Pages : 528

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Book Description
First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

Thin Layer Chromatography in Drug Analysis

Thin Layer Chromatography in Drug Analysis PDF Author: Lukasz Komsta
Publisher: CRC Press
ISBN: 1466507152
Category : Medical
Languages : en
Pages : 1070

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Book Description
Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date, complete reference, Thin Layer Chromatography in Drug Analysis covers the most important methods in pharmaceutical applications of TLC, namely, analysis of bulk drug material and pharmaceutical formulations, degradation studies, analysis of biological samples, optimization of the separation of drug classes, and lipophilicity estimation. The book is divided into two parts. Part I is devoted to general topics related to TLC in the context of drug analysis, including the chemical basis of TLC, sample pleparation, the optimization of layers and mobile phases, detection and quantification, analysis of ionic compounds, and separation and analysis of chiral substances. The text addresses the newest advances in TLC instrumentation, two-dimensional TLC, quantification by slit scanning densitometry and image analysis, statistical processing of data, and various detection and identification methods. It also describes the use of TLC for solving a key issue in the drug market—the presence of substandard and counterfeit pharmaceutical products. Part II provides an in-depth overview of a wide range of TLC applications for separation and analysis of particular drug groups. Each chapter contains an introduction about the structures and medicinal actions of the described substances and a literature review of their TLC analysis. A useful resource for chromatographers, pharmacists, analytical chemists, students, and R&D, clinical, and forensic laboratories, this book can be utilized as a manual, reference, and teaching source.

Complexation Chromatography

Complexation Chromatography PDF Author: D. Cagniant
Publisher: CRC Press
ISBN: 1000104702
Category : Science
Languages : en
Pages : 311

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Book Description
Considers three fundamental aspects of molecular interactions important in chromatography, taking care not to duplicate information readily available in other references. Surveys the basic factors involved in complex formation, which governs the retention mechanism and selectivity in either donor or

Capillary Electrophoresis of Proteins

Capillary Electrophoresis of Proteins PDF Author: Tim Wehr
Publisher: CRC Press
ISBN: 9780824702052
Category : Science
Languages : en
Pages : 308

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Book Description
"Provides practical information on the application of capillary electrophoresis (CE) to protein analysis, with an emphasis on developing and optimizing CE techniques in the laboratory. Includes separation methods bases on mass, charge, isoelectric point, molecular sieving, and affinity interactions."

Micellar Liquid Chromatography

Micellar Liquid Chromatography PDF Author: Alain Berthod
Publisher: CRC Press
ISBN: 1482273810
Category : Science
Languages : en
Pages : 632

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Book Description
Micellar Liquid Chromatography reviews the use of surfactant solutions at or above the critical micelle concentration as mobile phases in liquid chromatography. It employs a computer-assisted optimization methodology and integrates micellar liquid chromatography (MLC) with other chromatographic and electrophoretic techniques using surfactants. It a

Chromatographic Detectors

Chromatographic Detectors PDF Author: Raymond P.W. Scott
Publisher: CRC Press
ISBN: 9780849383670
Category : Science
Languages : en
Pages : 544

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Book Description
"Comprehensively covers the design, construction, and operation of gas chromatography, liquid chromatography, and thin-layer chromatography detectors--all in one convenient, up-to-date source. Emphasizes the essential use of common specifications to describe all detectors, allowing easy comparison of their attributes."