Functional Mapping of the Brain in Vascular Disorders PDF Download
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Author: W.-D. Heiss
Publisher: Springer Science & Business Media
ISBN: 3642707203
Category : Medical
Languages : en
Pages : 131
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Book Description
This book contains the contributions to the symposium "Functional Mapping of the Brain in Vascular Disorders", held at the Thirteenth World Congress of Neurology, Sep tember 1-6, 1985 in Hamburg, FRG. I have to thank the contributors to this symposium for submitting their manu scripts long before the congress so that the printed procee dings could be distributed to the audience. I hope that this will enable the participants in this symposium not only to recall the vivid presentation of the lectures and the highlights of the discussions, but also to widen their knowlegde of the topics dealt with during the symposium by rereading the chapters on the various issues. I would also like to express my thanks to the company UCB, Kerpen, FRG, who sup ported the symposium and the printing of these proceedings. W.-D. HEISS Cologne, July 1985 Contents The Purpose of Functional Mapping in Focal Cerebral Ischemia W.-D. Heiss ... 1 Positron Emission Tomography Versus Nuclear Magnetic Resonance Imaging? M.M. Ter-Pogossian (With 1 Figure) ... 5 Aims on Phosphorus-3l Magnetic Resonance Imaging K. Kogure, H. Ohtomo, S. Matsui, and H. Kohno (With 10 Figures) ... 15 In Vivo Nuclear Magnetic Resonance Imaging of Sodium-23 in the Human Head S.K. Hilal, A.A. Maudsley, J.B. Ra, H.E. Simon, P. Roschmann, S. Wittekoek, Z.H. Cho, and S.K. Mun (With 5 Figures) ... 29 Uncoupling of Flow and Metabolism in Infarcted Tissue T. Jones, R.J.S. Wise, R.S.J. Frackowiak, J.M.
Author: W.-D. Heiss
Publisher: Springer Science & Business Media
ISBN: 3642707203
Category : Medical
Languages : en
Pages : 131
Get Book Here
Book Description
This book contains the contributions to the symposium "Functional Mapping of the Brain in Vascular Disorders", held at the Thirteenth World Congress of Neurology, Sep tember 1-6, 1985 in Hamburg, FRG. I have to thank the contributors to this symposium for submitting their manu scripts long before the congress so that the printed procee dings could be distributed to the audience. I hope that this will enable the participants in this symposium not only to recall the vivid presentation of the lectures and the highlights of the discussions, but also to widen their knowlegde of the topics dealt with during the symposium by rereading the chapters on the various issues. I would also like to express my thanks to the company UCB, Kerpen, FRG, who sup ported the symposium and the printing of these proceedings. W.-D. HEISS Cologne, July 1985 Contents The Purpose of Functional Mapping in Focal Cerebral Ischemia W.-D. Heiss ... 1 Positron Emission Tomography Versus Nuclear Magnetic Resonance Imaging? M.M. Ter-Pogossian (With 1 Figure) ... 5 Aims on Phosphorus-3l Magnetic Resonance Imaging K. Kogure, H. Ohtomo, S. Matsui, and H. Kohno (With 10 Figures) ... 15 In Vivo Nuclear Magnetic Resonance Imaging of Sodium-23 in the Human Head S.K. Hilal, A.A. Maudsley, J.B. Ra, H.E. Simon, P. Roschmann, S. Wittekoek, Z.H. Cho, and S.K. Mun (With 5 Figures) ... 29 Uncoupling of Flow and Metabolism in Infarcted Tissue T. Jones, R.J.S. Wise, R.S.J. Frackowiak, J.M.
Author: W -D Heiss
Publisher:
ISBN: 9783642707216
Category :
Languages : en
Pages : 140
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Book Description
Author: Francesco Signorelli
Publisher: BoD – Books on Demand
ISBN: 9535111604
Category : Medical
Languages : en
Pages : 526
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Book Description
Functional brain mapping has by now gained a high impact on research and clinical practice: huge funds are unveiled all over the world in order to boost the research and clinical applications of this field of neuroscience. The most successful approach to unlock the mysteries of the brain, to tell it with Jay Ingram, is to bring together an interdisciplinary network of scientists and clinicians and encourage an interchange of ideas. It is this crossfire we try to promote with this book.
Author: Udunna C. Anazodo
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
There is growing interest in the role of vascular disease in accelerating age-related decline in cerebrovascular structural and functional integrity. Since an increased number of older adults are surviving chronic diseases, of which cardiovascular disease (CVD) is prevalent, there is an urgent need to understand relationships between cardiovascular dysfunction and brain health. It is unclear if CVD puts the brains of older adults, already experiencing natural brain aging, at greater risk for degeneration. In this thesis, the role of CVD in accelerating brain aging is explored. Because physical activity is known to provide neuroprotective benefits to brains of older adults, the role of physical activity in mediating disease effects were also explored. Using novel neuroimaging techniques, measures of gray matter volume and cerebrovascular hemodynamics were compared between groups of coronary artery disease patients and age-matched controls, to describe regional effects of CVD on the brain. In a sub-set of patients, imaging measures were repeated after completion of a 6-month exercise training, part of a cardiac rehabilitation program, to examine exercise effects. Differences in cerebrovascular hemodynamics were measured as changes in resting cerebral blood flow (CBF) and changes in cerebrovascular reactivity (CVR) to hypercapnia (6% CO2) using a non-invasive perfusion magnetic resonance imaging technique, arterial spin labelling (ASL). We found decreased brain volume, CBF and CVR in several regions of the brains of coronary artery disease patients compared to age-matched healthy controls. The reductions in CBF and CVR were independent of underlying brain atrophy, suggesting that changes in cerebrovascular function could precede changes in brain structure. In addition, increase in brain volume and CBF were observed in some regions of the brain after exercise training, indicating that cardiac rehabilitation programs may have neurorehabiliation effects as well. Since, CBF measured with ASL is not the [gold] standard measure of functional brain activity, we examined the regional correlation of ASL-CBF to glucose consumption rates (CMRglc) measured with positron emission tomography (PET), a widely acceptable marker of brain functional activity. Simultaneous measurements of ASL-CBF and PET-CMRglc were performed in a separate study in a group of older adults with no neurological impairment. Across brain regions, ASL-CBF correlated well with PET-CMRglc, but variations in regional coupling were found and demonstrate the role of certain brain regions in maintaining higher level of functional organization compared to other regions. In general, the results of the thesis demonstrate the impact of CVD on brain health, and the neurorehabiliation capacity of cardiac rehabilitation. The work presented also highlights the ability of novel non-invasive neuroimaging techniques in detecting and monitoring subtle but robust changes in the aging human brain.
Author: Yu Chen
Publisher: CRC Press
ISBN: 1315355744
Category : Medical
Languages : en
Pages : 669
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Book Description
Understanding how the brain works and developing effective therapeutics are important in advancing neuroscience and improving clinical patient care. Neurophotonics and Brain Mapping covers state-of-the-art research and development in optical technologies and applications for brain mapping and therapeutics. It provides a comprehensive overview of various methods developed using light, both microscopic and macroscopic techniques. Recent developments in minimally-invasive endoscopic imaging of deep brain structure and function, as well as light-based therapy are also reviewed.
Author: Norihiko Tamaki
Publisher: Springer
ISBN: 9784431701545
Category : Medical
Languages : en
Pages : 210
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Book Description
Recent advances in technology have opened up new possibilities in the diagnosis and treatment of cerebrospinal vascular diseases. It is now possible to use magnetic resonance imaging to map brain function and metabolism as an aid to diagnosis. Novel applications of magnetic resonance angiography allow three-dimensional imaging, and the magnetization transfer contrast technique gives us a new window on cerebral vascular function. This volume presents work in all these fields as well as previewing the techniques of endovascular surgery for cerebrospinal vascular diseases. These include modern stereotactic radiosurgery for arteriovenous malformations and for angiographically occult vascular malformations of the brain. This book presents an overview of the latest applications of technology to this rapidly developing and challenging field.
Author: Marilyn J. Cipolla
Publisher: Biota Publishing
ISBN: 1615047239
Category : Medical
Languages : en
Pages : 82
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Book Description
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Author: David R. Riddle
Publisher: CRC Press
ISBN: 9781420005523
Category : Medical
Languages : en
Pages : 408
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Book Description
Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur
Author: Leonardo Pantoni
Publisher: Cambridge University Press
ISBN: 1107031664
Category : Medical
Languages : en
Pages : 375
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Book Description
Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Author: Steven C. Cramer
Publisher: Cambridge University Press
ISBN: 1139490656
Category : Medical
Languages : en
Pages : 307
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Book Description
Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
