Functional Imaging Connectome of the Human Brain and Its Associations with Biological and Behavioral Characteristics PDF Download
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Author: Chao Zhang
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 153
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Book Description
"Functional connectome of the human brain explores the temporal associations of different brain regions. Functional connectivity (FC) measures derived from resting state functional magnetic resonance imaging (rfMRI) characterize the brain network at rest and studies have shown that rfMRI FC is closely related to individual subject's biological and behavioral measures. In this thesis we investigate a large rfMRI dataset from the Human Connectome Project (HCP) and utilize statistical methods to facilitate the understanding of fundamental FC-behavior associations of the human brain. Our studies include reliability analysis of FC statistics, demonstration of FC spatial patterns, and predictive analysis of individual biological and behavioral measures using FC features. Covering both static and dynamic FC (sFC and dFC) characterizations, the baseline FC patterns in healthy young adults are illustrated. Predictive analyses demonstrate that individual biological and behavioral measures, such as gender, age, fluid intelligence and language scores, can be predicted using FC. While dFC by itself performs worse than sFC in prediction accuracy, if appropriate parameters and models are utilized, adding dFC features to sFC can significantly increase the predictive power. Results of this thesis contribute to the understanding of the neural underpinnings of individual biological and behavioral differences in the human brain."--Abstract.
Author: Chao Zhang
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 153
Get Book Here
Book Description
"Functional connectome of the human brain explores the temporal associations of different brain regions. Functional connectivity (FC) measures derived from resting state functional magnetic resonance imaging (rfMRI) characterize the brain network at rest and studies have shown that rfMRI FC is closely related to individual subject's biological and behavioral measures. In this thesis we investigate a large rfMRI dataset from the Human Connectome Project (HCP) and utilize statistical methods to facilitate the understanding of fundamental FC-behavior associations of the human brain. Our studies include reliability analysis of FC statistics, demonstration of FC spatial patterns, and predictive analysis of individual biological and behavioral measures using FC features. Covering both static and dynamic FC (sFC and dFC) characterizations, the baseline FC patterns in healthy young adults are illustrated. Predictive analyses demonstrate that individual biological and behavioral measures, such as gender, age, fluid intelligence and language scores, can be predicted using FC. While dFC by itself performs worse than sFC in prediction accuracy, if appropriate parameters and models are utilized, adding dFC features to sFC can significantly increase the predictive power. Results of this thesis contribute to the understanding of the neural underpinnings of individual biological and behavioral differences in the human brain."--Abstract.
Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173
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Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Author: Olaf Sporns
Publisher: MIT Press
ISBN: 0262304805
Category : Medical
Languages : en
Pages : 253
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Book Description
A pioneer in the field outlines new empirical and computational approaches to mapping the neural connections of the human brain. Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. In this book, Olaf Sporns surveys current efforts to chart these connections—to map the human connectome. He argues that the nascent field of connectomics has already begun to influence the way many neuroscientists collect, analyze, and think about their data. Moreover, the idea of mapping the connections of the human brain in their entirety has captured the imaginations of researchers across several disciplines including human cognition, brain and mental disorders, and complex systems and networks. Discovering the Human Connectome offers the first comprehensive overview of current empirical and computational approaches in this rapidly developing field.
Author: Michelle Hampson
Publisher: Academic Press
ISBN: 0128224363
Category : Computers
Languages : en
Pages : 366
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Book Description
fMRI Neurofeedback provides a perspective on how the field of functional magnetic resonance imaging (fMRI) neurofeedback has evolved, an introduction to state-of-the-art methods used for fMRI neurofeedback, a review of published neuroscientific and clinical applications, and a discussion of relevant ethical considerations. It gives a view of the ongoing research challenges throughout and provides guidance for researchers new to the field on the practical implementation and design of fMRI neurofeedback protocols. This book is designed to be accessible to all scientists and clinicians interested in conducting fMRI neurofeedback research, addressing the variety of different knowledge gaps that readers may have given their varied backgrounds and avoiding field-specific jargon. The book, therefore, will be suitable for engineers, computer scientists, neuroscientists, psychologists, and physicians working in fMRI neurofeedback. Provides a reference on fMRI neurofeedback covering history, methods, mechanisms, clinical applications, and basic research, as well as ethical considerations Offers contributions from international experts—leading research groups are represented, including from Europe, Japan, Israel, and the United States Includes coverage of data analytic methods, study design, neuroscience mechanisms, and clinical considerations Presents a perspective on future translational development
Author: Aron K. Barbey
Publisher: Cambridge University Press
ISBN: 1108573746
Category : Psychology
Languages : en
Pages : 624
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Book Description
This handbook introduces the reader to the thought-provoking research on the neural foundations of human intelligence. Written for undergraduate or graduate students, practitioners, and researchers in psychology, cognitive neuroscience, and related fields, the chapters summarize research emerging from the rapidly developing neuroscience literature on human intelligence. The volume focusses on theoretical innovation and recent advances in the measurement, modelling, and characterization of the neurobiology of intelligence differences, especially from brain imaging studies. It summarizes fundamental issues in the characterization and measurement of general intelligence, and surveys multidisciplinary research consortia and large-scale data repositories for the study of general intelligence. A systematic review of neuroimaging methods for studying intelligence is provided, including structural and diffusion-weighted MRI techniques, functional MRI methods, and spectroscopic imaging of metabolic markers of intelligence.
Author: Mikhail I. Rabinovich
Publisher: MIT Press
ISBN: 0262549905
Category : Medical
Languages : en
Pages : 371
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Book Description
Experimental and theoretical approaches to global brain dynamics that draw on the latest research in the field. The consideration of time or dynamics is fundamental for all aspects of mental activity—perception, cognition, and emotion—because the main feature of brain activity is the continuous change of the underlying brain states even in a constant environment. The application of nonlinear dynamics to the study of brain activity began to flourish in the 1990s when combined with empirical observations from modern morphological and physiological observations. This book offers perspectives on brain dynamics that draw on the latest advances in research in the field. It includes contributions from both theoreticians and experimentalists, offering an eclectic treatment of fundamental issues. Topics addressed range from experimental and computational approaches to transient brain dynamics to the free-energy principle as a global brain theory. The book concludes with a short but rigorous guide to modern nonlinear dynamics and their application to neural dynamics.
Author: Alex Fornito
Publisher: Academic Press
ISBN: 0124081185
Category : Medical
Languages : en
Pages : 496
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Book Description
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Author: Deepak N. Pandya
Publisher: Oxford University Press, USA
ISBN: 0195385152
Category : Medical
Languages : en
Pages : 481
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Book Description
This unique book provides a new view of the organization of the cerebral cortex. It explores the underlying principle of the organization of the cerebral cortex using the dual nature of the origin of the cerebral cortex. Cerebral Cortex provides a different way of understanding the current behavioral studies, neuroimaging observations, and promises a new approach to future studies.
Author: Sergey N. Makarov
Publisher: Springer Nature
ISBN: 3030456234
Category : Biomedical engineering
Languages : en
Pages : 395
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Book Description
The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.
Author: Nitish V. Thakor
Publisher: Springer Nature
ISBN: 9811655405
Category : Technology & Engineering
Languages : en
Pages : 3686
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Book Description
This Handbook serves as an authoritative reference book in the field of Neuroengineering. Neuroengineering is a very exciting field that is rapidly getting established as core subject matter for research and education. The Neuroengineering field has also produced an impressive array of industry products and clinical applications. It also serves as a reference book for graduate students, research scholars and teachers. Selected sections or a compendium of chapters may be used as “reference book” for a one or two semester graduate course in Biomedical Engineering. Some academicians will construct a “textbook” out of selected sections or chapters. The Handbook is also meant as a state-of-the-art volume for researchers. Due to its comprehensive coverage, researchers in one field covered by a certain section of the Handbook would find other sections valuable sources of cross-reference for information and fertilization of interdisciplinary ideas. Industry researchers as well as clinicians using neurotechnologies will find the Handbook a single source for foundation and state-of-the-art applications in the field of Neuroengineering. Regulatory agencies, entrepreneurs, investors and legal experts can use the Handbook as a reference for their professional work as well.
