From Photon to Neuron

From Photon to Neuron PDF Author: Philip Nelson
Publisher: Princeton University Press
ISBN: 0691175195
Category : Science
Languages : en
Pages : 512

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Book Description
What is light? -- Photons and life -- Color vision -- How photons know where to go -- Optical phenomena and life -- Direct image formation -- Imaging as inference -- Imaging by X-ray diffraction -- Vision in dim light -- The mechanism of visual transduction -- The first synapse and beyond -- Electrons, photons, and the Feynman principle -- Field quantization, polarization, and the orientation of a single molecule -- Quantum-mechanical theory of FRET

From Photon to Neuron

From Photon to Neuron PDF Author: Philip Nelson
Publisher: Princeton University Press
ISBN: 0691175195
Category : Science
Languages : en
Pages : 512

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Book Description
What is light? -- Photons and life -- Color vision -- How photons know where to go -- Optical phenomena and life -- Direct image formation -- Imaging as inference -- Imaging by X-ray diffraction -- Vision in dim light -- The mechanism of visual transduction -- The first synapse and beyond -- Electrons, photons, and the Feynman principle -- Field quantization, polarization, and the orientation of a single molecule -- Quantum-mechanical theory of FRET

From Photon to Neuron

From Photon to Neuron PDF Author: Philip Nelson
Publisher: Princeton University Press
ISBN: 1400885485
Category : Science
Languages : en
Pages : 512

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Book Description
A richly illustrated undergraduate textbook on the physics and biology of light Students in the physical and life sciences, and in engineering, need to know about the physics and biology of light. Recently, it has become increasingly clear that an understanding of the quantum nature of light is essential, both for the latest imaging technologies and to advance our knowledge of fundamental life processes, such as photosynthesis and human vision. From Photon to Neuron provides undergraduates with an accessible introduction to the physics of light and offers a unified view of a broad range of optical and biological phenomena. Along the way, this richly illustrated textbook builds the necessary background in neuroscience, photochemistry, and other disciplines, with applications to optogenetics, superresolution microscopy, the single-photon response of individual photoreceptor cells, and more. With its integrated approach, From Photon to Neuron can be used as the basis for interdisciplinary courses in physics, biophysics, sensory neuroscience, biophotonics, bioengineering, or nanotechnology. The goal is always for students to gain the fluency needed to derive every result for themselves, so the book includes a wealth of exercises, including many that guide students to create computer-based solutions. Supplementary online materials include real experimental data to use with the exercises. Assumes familiarity with first-year undergraduate physics and the corresponding math Overlaps the goals of the MCAT, which now includes data-based and statistical reasoning Advanced chapters and sections also make the book suitable for graduate courses An Instructor's Guide and illustration package is available to professors

In Vivo Optical Imaging of Brain Function, Second Edition

In Vivo Optical Imaging of Brain Function, Second Edition PDF Author: Ron D. Frostig
Publisher: CRC Press
ISBN: 142007685X
Category : Science
Languages : en
Pages : 428

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Book Description
These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.

Physical Models of Living Systems

Physical Models of Living Systems PDF Author: Philip Nelson
Publisher: Macmillan Higher Education
ISBN: 1319036902
Category : Science
Languages : en
Pages : 365

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Book Description
Written for intermediate-level undergraduates pursuing any science or engineering major, Physical Models of Living Systems helps students develop many of the competencies that form the basis of the new MCAT2015. The only prerequisite is first-year physics. With the more advanced "Track-2" sections at the end of each chapter, the book can be used in graduate-level courses as well.

Vision Science

Vision Science PDF Author: Stephen E. Palmer
Publisher: CUP Archive
ISBN: 9780262161831
Category : Medical
Languages : en
Pages : 844

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Book Description
This textbook on vision reflects the integrated computational approach of modern research scientists, combining psychological, computational and neuroscientific perspectives.

Photons and Neurons

Photons and Neurons PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description


A Student's Guide to Python for Physical Modeling

A Student's Guide to Python for Physical Modeling PDF Author: Jesse M. Kinder
Publisher: Princeton University Press
ISBN: 0691223661
Category : Science
Languages : en
Pages : 241

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Book Description
A fully updated tutorial on the basics of the Python programming language for science students Python is a computer programming language that has gained popularity throughout the sciences. This fully updated second edition of A Student's Guide to Python for Physical Modeling aims to help you, the student, teach yourself enough of the Python programming language to get started with physical modeling. You will learn how to install an open-source Python programming environment and use it to accomplish many common scientific computing tasks: importing, exporting, and visualizing data; numerical analysis; and simulation. No prior programming experience is assumed. This guide introduces a wide range of useful tools, including: Basic Python programming and scripting Numerical arrays Two- and three-dimensional graphics Animation Monte Carlo simulations Numerical methods, including solving ordinary differential equations Image processing Numerous code samples and exercises—with solutions—illustrate new ideas as they are introduced. This guide also includes supplemental online resources: code samples, data sets, tutorials, and more. This edition includes new material on symbolic calculations with SymPy, an introduction to Python libraries for data science and machine learning (pandas and sklearn), and a primer on Python classes and object-oriented programming. A new appendix also introduces command line tools and version control with Git.

Biophysics

Biophysics PDF Author: William Bialek
Publisher: Princeton University Press
ISBN: 1400845572
Category : Science
Languages : en
Pages : 640

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Book Description
Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology--from the discovery of DNA's structure to imaging of the human brain--have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles--the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes Instructor's manual (available only to teachers)

Neurophotonics and Biomedical Spectroscopy

Neurophotonics and Biomedical Spectroscopy PDF Author: Robert R. Alfano
Publisher: William Andrew
ISBN: 0323480683
Category : Technology & Engineering
Languages : en
Pages : 610

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Book Description
Neurophotonics and Biomedical Spectroscopy addresses the novel state-of-the-art work in non-invasive optical spectroscopic methods that detect the onset and progression of diseases and other conditions, including pre-malignancy, cancer, Alzheimer’s disease, tissue and cell response to therapeutic intervention, unintended injury and laser energy deposition. The book then highlights research in neurophotonics that investigates single and multi-photon excitation optical signatures of normal/diseased nerve tissues and in the brain, providing a better understanding of the underlying biochemical and structural changes of tissues and cells that are responsible for the observed spectroscopic signatures. Topics cover a wide array of well-established UV, visible, NIR and IR optical and spectroscopic techniques and novel approaches to diagnose tissue changes, including: label free in vivo and ex vivo fluorescence spectroscopy, Stoke shift spectroscopy, spectral imaging, Resonance Raman spectroscopy, multiphoton two Photon excitation, and more. Provides an overview of the spectroscopic properties of tissue and tissue-light interaction, describing techniques to exploit these properties in imaging Explores the potential and significance of molecule-specific imaging and its capacity to reveal vital new information on nanoscale structures Offers a concise overview of different spectroscopic methods and their potential benefits for solving diagnostic and therapeutic problems

The Synaptic Organization of the Brain

The Synaptic Organization of the Brain PDF Author: Gordon M. Shepherd
Publisher: Oxford University Press
ISBN: 019515956X
Category : Medical
Languages : en
Pages : 736

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Book Description
This is a thorough revision of the standard text on local circuits in the different regions of the brain. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioral and gene-targeting methods.