Free Radical Effects on Membranes

Free Radical Effects on Membranes PDF Author:
Publisher: Academic Press
ISBN: 0080920470
Category : Science
Languages : en
Pages : 297

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Book Description
Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. This volume consist of eleven chapters from experts in the field that encompass free-radical effects on diverse membrane functions, ranging from selective barrier functions, controlling membrane protein function to discussing how the hydrophobic environment within membranes regulate free radical reactivity. The focus is on articles discussing specific examples in which membranes from different cellular compartments (e.g. plasma, ER, mitochondria) and membrane proteins either regulate reactive species formation and reactivity or are specific targets of reactive species leading to alteration in function. - Provides overviews on biomembranes and the impact their physico-chemical properties have on reactive species reactivity - Focuses is on reactive species and control of cell-signaling pathways - Illustrates the concept that different reactive species can modulate function of specific membrane ion channels in different tissues, including sodium channels, chloride channels, sodium-potassium ATPases and calcium channels in both plasma and intracellular organelle membranes

Free Radical Effects on Membranes

Free Radical Effects on Membranes PDF Author:
Publisher: Academic Press
ISBN: 0080920470
Category : Science
Languages : en
Pages : 297

Get Book Here

Book Description
Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. This volume consist of eleven chapters from experts in the field that encompass free-radical effects on diverse membrane functions, ranging from selective barrier functions, controlling membrane protein function to discussing how the hydrophobic environment within membranes regulate free radical reactivity. The focus is on articles discussing specific examples in which membranes from different cellular compartments (e.g. plasma, ER, mitochondria) and membrane proteins either regulate reactive species formation and reactivity or are specific targets of reactive species leading to alteration in function. - Provides overviews on biomembranes and the impact their physico-chemical properties have on reactive species reactivity - Focuses is on reactive species and control of cell-signaling pathways - Illustrates the concept that different reactive species can modulate function of specific membrane ion channels in different tissues, including sodium channels, chloride channels, sodium-potassium ATPases and calcium channels in both plasma and intracellular organelle membranes

Fundamentals of Medical Physiology

Fundamentals of Medical Physiology PDF Author: Joel Michael
Publisher: Thieme
ISBN: 1604062754
Category : Medical
Languages : en
Pages : 1676

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Book Description
Fundamentals of Medical Physiology provides a concise, in-depth introduction by organ system to the principles of body function and uses emphasis on general models and clinical cases to foster mastery of these principles.Special features include: An emphasis on general models that underlie a number of recurring physiologic mechanisms -- for example, flow of substances and the factors that affect flow or energy formation and transformation -- to strengthen understanding Use of clinical cases -- developed, refined, and tested in the classroom over the past decade -- to test mastery of physiologic concepts Section-opening Patient Cases conclude with Some Things to Think About to help direct your study of the physiologic mechanisms of that organ system Chapter Questions ask you to apply what you have learned in that chapter to building an understanding of the case Answers to chapter questions allow you to check your understanding and direct further review A comprehensive Case Analysis with cause-and-effect diagrams reviews in detail the physiology behind the case Access via scratch-off code to all the cases in your book -- plus additional clinical cases -- with questions and answers and case analysis to enable convenient online review and testing Specifically, designed for the first- and second-year medical student, this innovative text -- ideal as a study aid for the USMLE -- provides the tools needed to learn and apply physiology to medical practice.

Oxidative Stress and Antioxidant Protection

Oxidative Stress and Antioxidant Protection PDF Author: Donald Armstrong
Publisher: John Wiley & Sons
ISBN: 1118832485
Category : Science
Languages : en
Pages : 610

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Book Description
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

Phytochemicals

Phytochemicals PDF Author: Toshiki Asao
Publisher: BoD – Books on Demand
ISBN: 1789843774
Category : Science
Languages : en
Pages : 220

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Book Description
Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Systems Biology of Free Radicals and Antioxidants

Systems Biology of Free Radicals and Antioxidants PDF Author: Ismail Laher
Publisher: Springer
ISBN: 9783642300172
Category : Medical
Languages : en
Pages : 0

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Book Description
The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.

Heavy Metal Stress in Plants

Heavy Metal Stress in Plants PDF Author: M.N.V. Prasad
Publisher: Springer Science & Business Media
ISBN: 3662077450
Category : Science
Languages : en
Pages : 405

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Book Description
Heavy metal phytotoxicity has been known for more than a century. However, research in the past years has confirmed the immense damage by metal pollution to plants, the soil and ultimately to humans. By reviewing both field and laboratory work, this book deals with the various functional and ecological aspects of heavy metal stress on plants and outlines the scope for future research and the possibilities for remediation.

Plant Aging

Plant Aging PDF Author: Roberto Rodríguez
Publisher: Springer Science & Business Media
ISBN: 1468457608
Category : Science
Languages : en
Pages : 425

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Book Description
For many, the terms aging, maturation and senescence are synonymous and used interchangeably, but they should not be. Whereas senescence represents an endogenously controlled degenerative programme leading to plant or organ death, genetiC aging encompasses a wide array of passive degenerative genetiC processes driven primarily by exogenous factors (Leopold, 1975). Aging is therefore considered a consequence of genetiC lesions that accumulate over time, but by themselves do not necessarily cause death. These lesions are probably made more severe by the increase in size and complexity in trees and their attendant physiology. Thus while the withering of flower petals following pollination can be considered senescence, the loss of viability of stored seeds more clearly represents aging (Norden, 1988). The very recent book "Senescence and Aging in Plants" does not discuss trees, the most dominant group of plants on the earth. Yet both angiospermic and gymnospermic trees also undergo the above phenomena but less is known about them. Do woody plants senesce or do they just age? What is phase change? Is this synonymous with maturation? While it is now becoming recognized that there is no programmed senescence in trees, senescence of their parts, even in gymnosperms (e. g. , needles of temperate conifers las t an average of 3. 5 years), is common; but aging is a readily acknowledged phenomenon. In theory, at least, in the absence of any programmed senescence trees should -live forever, but in practice they do not.

Polyphenols: Mechanisms of Action in Human Health and Disease

Polyphenols: Mechanisms of Action in Human Health and Disease PDF Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 0128130075
Category : Science
Languages : en
Pages : 472

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Book Description
Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. - Expands coverage on green tea, cocoa, wine, cumin and herbs - Outlines their chemical properties, bioavailability and metabolomics - Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Accenting Lipid Peroxidation

Accenting Lipid Peroxidation PDF Author: Pınar Atukeren
Publisher: BoD – Books on Demand
ISBN: 1839688254
Category : Science
Languages : en
Pages : 160

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Book Description
Lipid peroxidation can occur via either enzymatic or nonenzymatic reactions due to excess production of free radical molecules. This process culminates in cellular damage causing various diseases. This book examines lipid peroxidation as a current and future biomarker of oxidative stress.

Brain Aging

Brain Aging PDF Author: David R. Riddle
Publisher: CRC Press
ISBN: 1420005529
Category : Medical
Languages : en
Pages : 413

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Book Description
Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur