The Metabolism and Toxicity of Fluoride PDF Download
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Author: Gary M. Whitford
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 180
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Book Description
Since the first edition of this highly-acclaimed book appeared in 1989, a considerable amount of new information has been published on the diverse effects that fluoride can produce in biological systems. The remarkable decline in dental caries that is now occurring throughout the world can be largely attributed to the use of ingested and topical forms of fluoride. Indeed, fluoride is now widely regarded as the cornerstone of modern preventive dentistry. In addition to its prophylactic qualities, fluoride is currently being investigated for its benefits in the treatment of osteoporosis, ischemia, and other major diseases; in larger doses, however, fluoride is known to cause fluorosis, and in excessive amounts can even lead to death. This newly revised edition includes data from the most recent studies in these areas and provides an up-to-date, critical discussion of fluoride metabolism and toxicity as well as environmental and physiological variables that can affect these processes. It will be of particular interest to dental students and residents, dental educators and researchers, toxicologists, pharmacologists and physiologists.
Author: Gary M. Whitford
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 180
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Book Description
Since the first edition of this highly-acclaimed book appeared in 1989, a considerable amount of new information has been published on the diverse effects that fluoride can produce in biological systems. The remarkable decline in dental caries that is now occurring throughout the world can be largely attributed to the use of ingested and topical forms of fluoride. Indeed, fluoride is now widely regarded as the cornerstone of modern preventive dentistry. In addition to its prophylactic qualities, fluoride is currently being investigated for its benefits in the treatment of osteoporosis, ischemia, and other major diseases; in larger doses, however, fluoride is known to cause fluorosis, and in excessive amounts can even lead to death. This newly revised edition includes data from the most recent studies in these areas and provides an up-to-date, critical discussion of fluoride metabolism and toxicity as well as environmental and physiological variables that can affect these processes. It will be of particular interest to dental students and residents, dental educators and researchers, toxicologists, pharmacologists and physiologists.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030910128X
Category : Nature
Languages : en
Pages : 531
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Book Description
Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural sources. Fluoride is one of the drinking water contaminants regulated by the U.S. Environmental Protection Agency (EPA) because it can occur at these toxic levels. In 1986, the EPA established a maximum allowable concentration for fluoride in drinking water of 4 milligrams per liter, a guideline designed to prevent the public from being exposed to harmful levels of fluoride. Fluoride in Drinking Water reviews research on various health effects from exposure to fluoride, including studies conducted in the last 10 years.
Author:
Publisher: Elsevier
ISBN: 0443236445
Category : Science
Languages : en
Pages : 378
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Book Description
Fluorine Metabolism, Transport and Enzymatic Chemistry, Volume 696 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Fluorine Metabolism, Transport, and Enzymatic Chemistry. Chapters in this new release include Determination of fluoride sensitivity and resistance in oral biofilm models, NMR methods to detect fluoride binding and transport by membrane proteins, Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans, Measurement of fluoride efflux from lipid vesicles and cells, Defluorination of PFAS by Acidimicrobium sp. A6 and Potential Applications for Remediation, and more. Additional chapters cover Computational approaches to investigate F- binding, selectivity and transport in F- exporters, Defluorination as a key trait to gauge the biodegradability of fluorinated pollutants: challenges and opportunities, Patch-Clamp Electrophysiology of Fluoride Channels in Saccharomyces cerevisiae, and Synthesis of fluorophenylalanine-encoded proteins in HEK cells. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology series Updated release includes the latest information on Fluorine Metabolism, Transport, and Enzymatic Chemistry
Author: Venkateswarlu Pothapragada
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 392
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Book Description
Author: M.A.R. Buzalaf
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805596596
Category : Medical
Languages : en
Pages : 190
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Book Description
This volume brings together current concepts relating to the use of fluoride in dentistry. In contributions written by expert authors, data from this large and complex field have been assembled into a clear sequence and presented in a lucid fashion. The first section deals with the sources of fluoride intake and its metabolism, in order to fully understand fluoride toxicity and the importance of monitoring intake. The second section focuses in more detail on modes of fluoride application and the mechanisms by which this ion interacts with the oral environment to cause a remarkable reduction in dental caries. The role of fluoride in the prevention of dental erosion is also elucidated. The complex mechanisms by which fluoride exerts its effects are described with clarity and the entire text is accompanied by particularly useful illustrations.As a clear up-to-date summary of current thinking in the field, this book will be essential reading for research workers and postgraduate students. Established researchers and teachers in both clinical and basic sciences will find it to be a valuable addition to their libraries, and clinicians will be able to better evaluate the current scientific evidence on the advantages as well as the hazards of fluoride in dentistry.
Author: Max Hohenegger
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 246
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Book Description
Author: Victor R Preedy
Publisher: Royal Society of Chemistry
ISBN: 1782624929
Category : Medical
Languages : en
Pages : 376
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Book Description
Fluorine is best known for its role in the prevention of cavities and in improving oral and bone health however equally there are millions of people around the world suffering from dental fluorosis due to chronic exposure to high levels of fluoride in drinking water. This volume, written by leading researchers in this area, examines the positives and negatives of fluorine and its effects on humans for example fluoride-induced oxidative stress in the liver, effects of fluoride on insulin and preventing fluoride toxicity. Extremely useful for underpinning cross-disciplinary fluorine research, this book provides a fascinating insight for those with an interest in the health and nutritional sciences.
Author: George K. Stookey
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 438
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Book Description
Author: Kurt Binder
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Nishu Singla
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659741869
Category :
Languages : en
Pages : 56
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Book Description
Fluoride is like a double-edged sword as it is proved to be one of the most successful measures for the prevention of dental caries in public-health history but at the same time its toxicity at higher levels has also been well established. In terms of fluoride toxicity, the high levels of fluoride in the system may have a range of the effects. These effects can be classified as acute, due to a single ingestion of a large amount of fluoride or chronic, due to long term ingestion of smaller amounts. To understand the biological effects of fluoride, a thorough knowledge of fluoride metabolism is necessary. This book explains in detail the various sources of fluoride intake, metabolism of fluorides, its toxicity, management and prevention.
