Finite Element Study of Transcranial Direct Current Stimulation PDF Download
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Author: Dennis Q.. Truong
Publisher:
ISBN:
Category :
Languages : en
Pages : 60
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Book Description
Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique that applies low amplitude current via electrodes placed on the scalp. Rather than directly eliciting a neuronal response, tDCS is believed to modulate excitability -- encouraging or suppressing activity in regions of the brain depending on the polarity of stimulation. The particular application of tDCS is often determined by the electrode configuration and intensity of stimulation. MRI-derived finite element models have been developed to analyze the effect of these parameters allowing novel electrode configurations to be tested in subject specific models. By creating a subject specific model of an obese subject, the effect of fat on tDCS was examined. The inclusion of fat into the model led to an increase in cortical electric field intensity. To further investigate the influence of fat the conductivity was varied from that of skull to that of skin. Cortical electric field intensity did not change monotonically with fat conductivity. It was postulated that this may be due to a shunting effect both when the shell of fat surrounding the skull is too resistive for penetration and when the fat is so conductive as to lead current around rather than through the head. The effect of electrode positioning was then examined in a new 2x1 Hybrid montage utilizing both HD electrodes and sponge pads. Systematically varying the location of both the anode and cathode led to changes in the electric field distribution. This is in contrast to the old heuristic convention of placing the "active" electrode over a region of interest and neglecting the influence of the "return" electrode. Lastly the radial directionality of electric field was examined in a 4x1 ring configuration. Previous models have predicted the spatial focality of the 4x1 ring configuration. Polarity specificity, the ability to selectively apply either anodal or cathodal stimulation, was demonstrated in a 4x1 montage over the motor strip. The customization of models for specific populations and montages provides new avenues for clinical practice.
Author: Dennis Q.. Truong
Publisher:
ISBN:
Category :
Languages : en
Pages : 60
Get Book Here
Book Description
Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique that applies low amplitude current via electrodes placed on the scalp. Rather than directly eliciting a neuronal response, tDCS is believed to modulate excitability -- encouraging or suppressing activity in regions of the brain depending on the polarity of stimulation. The particular application of tDCS is often determined by the electrode configuration and intensity of stimulation. MRI-derived finite element models have been developed to analyze the effect of these parameters allowing novel electrode configurations to be tested in subject specific models. By creating a subject specific model of an obese subject, the effect of fat on tDCS was examined. The inclusion of fat into the model led to an increase in cortical electric field intensity. To further investigate the influence of fat the conductivity was varied from that of skull to that of skin. Cortical electric field intensity did not change monotonically with fat conductivity. It was postulated that this may be due to a shunting effect both when the shell of fat surrounding the skull is too resistive for penetration and when the fat is so conductive as to lead current around rather than through the head. The effect of electrode positioning was then examined in a new 2x1 Hybrid montage utilizing both HD electrodes and sponge pads. Systematically varying the location of both the anode and cathode led to changes in the electric field distribution. This is in contrast to the old heuristic convention of placing the "active" electrode over a region of interest and neglecting the influence of the "return" electrode. Lastly the radial directionality of electric field was examined in a 4x1 ring configuration. Previous models have predicted the spatial focality of the 4x1 ring configuration. Polarity specificity, the ability to selectively apply either anodal or cathodal stimulation, was demonstrated in a 4x1 montage over the motor strip. The customization of models for specific populations and montages provides new avenues for clinical practice.
Author: Sergey Makarov
Publisher: Springer Nature
ISBN: 3030212939
Category : Technology & Engineering
Languages : en
Pages : 398
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Book Description
This open access book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner. Describes construction and application of computational human models including anatomically detailed and subject specific models; Explains new practices in computational human modeling for neuroelectromagnetics, electromagnetic safety, and exposure evaluations; Includes a survey of modern applications for which computational human models are critical; Describes cellular-level interactions between the human body and electromagnetic fields.
Author: Sergey N. Makarov
Publisher: Springer Nature
ISBN: 3030456234
Category : Biomedical engineering
Languages : en
Pages : 395
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Book Description
The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.
Author: Todd C. Handy
Publisher: MIT Press
ISBN: 9780262083331
Category : Evoked potentials (Electrophysiology)
Languages : en
Pages : 430
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Book Description
The first comprehensive handbook to detail ERP methodology, covering experimental design, data analysis, and special applications.
Author: Chwee Teck Lim
Publisher: Springer Science & Business Media
ISBN: 3540928413
Category : Technology & Engineering
Languages : en
Pages : 2355
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Book Description
th On behalf of the organizing committee of the 13 International Conference on Biomedical Engineering, I extend our w- mest welcome to you. This series of conference began in 1983 and is jointly organized by the YLL School of Medicine and Faculty of Engineering of the National University of Singapore and the Biomedical Engineering Society (Singapore). First of all, I want to thank Mr Lim Chuan Poh, Chairman A*STAR who kindly agreed to be our Guest of Honour to give th the Opening Address amidst his busy schedule. I am delighted to report that the 13 ICBME has more than 600 participants from 40 countries. We have received very high quality papers and inevitably we had to turndown some papers. We have invited very prominent speakers and each one is an authority in their field of expertise. I am grateful to each one of them for setting aside their valuable time to participate in this conference. For the first time, the Biomedical Engineering Society (USA) will be sponsoring two symposia, ie “Drug Delivery S- tems” and “Systems Biology and Computational Bioengineering”. I am thankful to Prof Tom Skalak for his leadership in this initiative. I would also like to acknowledge the contribution of Prof Takami Yamaguchi for organizing the NUS-Tohoku’s Global COE workshop within this conference. Thanks also to Prof Fritz Bodem for organizing the symposium, “Space Flight Bioengineering”. This year’s conference proceedings will be published by Springer as an IFMBE Proceedings Series.
Author: André R. Brunoni
Publisher: Springer Nature
ISBN: 3030761363
Category : Medical
Languages : en
Pages : 779
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Book Description
The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years. Since the 1st edition was published, the clinical use of tDCS has moved from its infancy, and is now in a thrilling new phase with numerous possibilities as well as challenges. tDCS is a technique that excels in terms of safety and tolerability, and within a few years, novel technological developments will allow its use at home. At the same time, large, phase III trials have been exploring the clinical efficacy of tDCS, the results of which have been published in leading journals such as the New England Journal of Medicine and JAMA Psychiatry. This 2nd edition summarizes the state of the art of the field. Written by leading experts in the field, the book is divided into 5 parts: Introduction and Mechanisms of Action; Research Methods; tDCS in the life cycle; Applications of tDCS in neuropsychiatric disorders (further divided into Psychiatry and Neurology); and The clinical use of tDCS. It also includes several new chapters, covering topics such as precision stimulation of tDCS; combination of tDCS with different neuroimaging modalities; and use of tDCS in new clinical conditions. Moreover, all chapters have been rewritten and updated. This book will be of significant interest to psychiatrists, neurologists and neuroscientists new to the field as well as those with a background in tDCS who want to increase their understanding of particular psychiatric conditions.
Author: Helena Knotkova
Publisher: Springer
ISBN: 3319959484
Category : Medical
Languages : en
Pages : 651
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Book Description
This book provides a comprehensive overview on Transcranial Direct Current Stimulation (tDCS) and the clinical applications of this promising technique. Separated into three parts, the book begins with basic principles, mechanisms and approaches of tDCS. This is followed by a step-by-step practicum, methodological considerations and ethics and professional conduct pertaining to this novel technique. Chapters are authored by renowned experts who also direct and plan tDCS educational events worldwide. Bridging the existing gap in instructional materials for tDCS while addressing growing interest in education in this field, professionals within a broad range of medical disciplines will find this text to be an invaluable guide.
Author: André Brunoni
Publisher: Springer
ISBN: 3319339672
Category : Medical
Languages : en
Pages : 421
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Book Description
The aim of this book is to provide a comprehensive review of the use of Transcranial Direct Current Stimulation (tDCS) in different psychiatric conditions. Here we review tDCS clinical studies employing different types of design (from single-session tDCS studies to randomized clinical trials) as well as studies evaluating the impact of tDCS in neurophysiological, behavioral and brain imaging outcomes. Although the understanding about physiological foundations and effectiveness of clinical therapies of psychiatric diseases has been considerably increased during the last decades, our knowledge is still limited, and consequently psychiatric diseases are still a major burden to the individual patient and society. Recently, interest in pathological alterations of neuroplasticity in psychiatric diseases as a critical condition for development, and amelioration of clinical symptoms increased, caused by the fact that new tools, such as functional imaging, and brain stimulation techniques do allow to monitor, and modulate these phenomena in humans. Especially non-invasive brain stimulation techniques evolved as an attractive potential new therapeutic tool. The interest in non-invasive brain stimulation has grown exponentially in the past 25 years, with the development of non-pharmacological, neuromodulatory techniques such as tDCS and repetitive transcranial magnetic stimulation (rTMS). TDCS, although even newer than rTMS, has attracted considerable attention in both basic and clinical research scenarios. In the context of clinical research, tDCS is being increasingly investigated as a novel treatment tool for several psychiatric disorders, such as major depression, schizophrenia and neurocognitive and substance abuse disorders. Transcranial Direct Current Stimulation in Neuropsychiatric Disorders – Clinical Principles and Management intends to serve as a practical guide on the field, attracting the interest of psychiatrists, neurologists and neuroscientists with little or no experience with tDCS, as well as those with a background on tDCS who want to increase their knowledge in any particular psychiatric condition.
Author: Alberto Priori
Publisher: Frontiers Media SA
ISBN: 2889192873
Category : Brain stimulation
Languages : en
Pages : 211
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Book Description
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Author: Roi Cohen Kadosh
Publisher: Elsevier
ISBN: 0124047122
Category : Medical
Languages : en
Pages : 568
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Book Description
The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds by exploring this fascinating field of research. Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers The only reference on the market to focus on transcranial electrical stimulation (tES) Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available
