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Author: James D. Crapo
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 400
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Book Description
Extrapolation Modeling, Advancements and Research Issues in Lung Dosimetry; Lung Structure, Function Relationships; Species Differences in Airway Cell Distribution and Morphology; Alternative Methods to Evaluate Species Differences in Upper Airway Structure, Function; Preparation of Rat Nasal Airway Casts and Their Application to Studies of Nasal Airflow; Age Related Morphometric Analysis of Human Lung Casts; Anatomical Modeling of Microdosimetry of Inhaled Particles and Gases in the Lung; Experimental Dosimetry; Particle Deposition at the Alveolar Duct Bifurcations; Effects of Airway Branch Angle, Branch Point Number, and Gravity on Particle Deposition and Retention; Regional Deposition of Inhaled Particulates in Conducting Airways and Lung Segments; The Physical Properties of Mainstream Cigarette Smoke and Their Relationship to Deposition in the Respiratory Tract; Localization of 14C Dotriacontane Labeled Cigarette Smoke Particulate in the Dog Lung; Human Lung Clearance Following Bolus Inhalation of Radioaerosols; Effects of Ventilatory Patterns and Pre-existing Disease on Deposition of Inhaled Particles in Animals; Nasopharyngeal Uptake of Ozone in Humans and Animals; New Methods; Regional Dosimetry of Inhaled Particles Using SPECT; Dual Laser Doppler System for Real Time, Simultaneous Characterization of Aerosols by Size and Concentration; Dosimetry of Inhaled Particles by Means of Light Scattering; Modeling Approaches; Issues That Must Be Addressed When Constructing Anatomical Models of the Developing Lung; Significances of the Variability of Tracheobronchial Airway Paths and Their Air Flow Rates to Dosimetry Model Predictions of the Absorption of Gases; Predicting Respiratory Tract Clearance in Man; The Role of Particle Hygroscopicity in Aerosol Therapy and Inhalation Toxicology; Age-Dependent Lung Dosimetry of Radon Progeny; Deposition and Retention Modeling of Inhaled Cadmium in Rat and Human Lung, An Example for Extrapolation of Effects and Risk Estimation.
Author: James D. Crapo
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 400
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Book Description
Extrapolation Modeling, Advancements and Research Issues in Lung Dosimetry; Lung Structure, Function Relationships; Species Differences in Airway Cell Distribution and Morphology; Alternative Methods to Evaluate Species Differences in Upper Airway Structure, Function; Preparation of Rat Nasal Airway Casts and Their Application to Studies of Nasal Airflow; Age Related Morphometric Analysis of Human Lung Casts; Anatomical Modeling of Microdosimetry of Inhaled Particles and Gases in the Lung; Experimental Dosimetry; Particle Deposition at the Alveolar Duct Bifurcations; Effects of Airway Branch Angle, Branch Point Number, and Gravity on Particle Deposition and Retention; Regional Deposition of Inhaled Particulates in Conducting Airways and Lung Segments; The Physical Properties of Mainstream Cigarette Smoke and Their Relationship to Deposition in the Respiratory Tract; Localization of 14C Dotriacontane Labeled Cigarette Smoke Particulate in the Dog Lung; Human Lung Clearance Following Bolus Inhalation of Radioaerosols; Effects of Ventilatory Patterns and Pre-existing Disease on Deposition of Inhaled Particles in Animals; Nasopharyngeal Uptake of Ozone in Humans and Animals; New Methods; Regional Dosimetry of Inhaled Particles Using SPECT; Dual Laser Doppler System for Real Time, Simultaneous Characterization of Aerosols by Size and Concentration; Dosimetry of Inhaled Particles by Means of Light Scattering; Modeling Approaches; Issues That Must Be Addressed When Constructing Anatomical Models of the Developing Lung; Significances of the Variability of Tracheobronchial Airway Paths and Their Air Flow Rates to Dosimetry Model Predictions of the Absorption of Gases; Predicting Respiratory Tract Clearance in Man; The Role of Particle Hygroscopicity in Aerosol Therapy and Inhalation Toxicology; Age-Dependent Lung Dosimetry of Radon Progeny; Deposition and Retention Modeling of Inhaled Cadmium in Rat and Human Lung, An Example for Extrapolation of Effects and Risk Estimation.
Author: Roger O. McClellan
Publisher: CRC Press
ISBN: 9781439805572
Category : Medical
Languages : en
Pages : 678
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Book Description
Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.
Author: Lev S. Ruzer
Publisher: CRC Press
ISBN: 0203493184
Category : Nature
Languages : en
Pages : 728
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Book Description
As more attention is dedicated to understanding the occupational health risks associated with the industrial manufacture and use of nanotechnology, Aerosols Handbook: Measurement, Dosimetry, and Health Effects is a timely presentation of time-tested research in the field of aerosol science. The book covers a multitude of topics in indoor, outdoor,
Author: S.D. Lee
Publisher: Elsevier
ISBN: 0080874940
Category : Science
Languages : en
Pages : 1067
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Book Description
These proceedings describe the current state-of-the-art of ozone research. A wide range of topics is discussed including: emissions, transport and transformation of precursors of ozone and of ozone itself, the distribution of ozone, the deposition of ozone at the earth's surface, and its effects on man and the environment. Attention is also given to the role of stratospheric ozone and the role of the ultraviolet radiation which is transmitted through the ozone layer. Finally it describes in detail present and future policy measures to reduce the ozone in the lower atmosphere and to protect the ozone layer in the stratosphere.Many of the papers describe recent developments and new research results. Research carried out in both in Europe and in the United States is described, as are the policy measures which are being taken by both European and U.S. governments.
Author: J.H. Vincent
Publisher: Elsevier
ISBN: 0080526853
Category : Science
Languages : en
Pages : 431
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Book Description
Aerosols in workplace atmospheres have been - and continue to be - a major focus of industrial hygiene. Although there are many existing texts on aerosol science and on occupational health respectively, this new book sets out to be complementary to these and to provide a link between the two fields. In particular, the central concept of worker exposure leads to a structured approach which draws together wide-ranging aspects of aerosol science within the occupational health framework. Introductory chapters are concerned with the nature and properties of aerosols, and how they are generated in the occupational environment. The book then goes on to provide a description of the fundamental mechanical properties of aerosols, in particular those mechanical properties associated with the motion of airborne particles (which govern particle transport, inhalation, deposition, sampling and control). There follows a description of the optical properties of workplace aerosols since these are important in the visual appearance of aerosols and in many aspects of measurement. The central core of the book deals with the processes which govern the nature of exposure to and the subsequent fate and effects of airborne particles, leading to a rational framework for standards, measurement and control. Finally, a chapter is added which relates what has been said about aerosols to gaseous and vapour contaminants. The book is aimed at graduate students and practitioners in industrial hygiene and other occupational (and environmental) health disciplines.
Author: D.V. Bates
Publisher: Springer Science & Business Media
ISBN: 3642771769
Category : Medical
Languages : en
Pages : 423
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Book Description
Advances in Controlled Clinical Inhalation Studies represents scientific work presented at the 3rd International Inhalation Symposium held 1991 in Hannover, FRG. The symposium covered the new developments in this field of research. The main pollutants of interest were acid aerosols, fog, and indoor pollutants, while with regard to biological effects, an emphasis was placed on immunotoxicological and biochemical parameters. Tests on high risk groups were also considered. Initial chapters describe the outdoor environment as well as indoor air, measurement and quality - both at home and in the workplace. Besides methods for clinical inhalation and assessing personal exposure, new methodologies are particularly presented. Further chapters focus on the relevance of clinical data for regulatory decisions.
Author: Anthony J. Hickey
Publisher: CRC Press
ISBN: 0824756649
Category : Medical
Languages : en
Pages : 628
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Book Description
This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.
Author: J.C. Marijnissen
Publisher: Springer Science & Business Media
ISBN: 9400916949
Category : Science
Languages : en
Pages : 399
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Book Description
A group of highly esteemed aerosol scientists - physicists, chemists, biologists and toxicologists - met in Warsaw in September, 1995, in order to discuss the latest developments in the field of aerosol health subjects, including inhalation, lung transport and deposition. The relationship of these subjects with the environment was also addressed. This book contains the proceedings of the Workshop and also documents the ensuing panel discussions. Subject Index included.
Author: Mitchell D. Cohen
Publisher: Springer Science & Business Media
ISBN: 1461545358
Category : Medical
Languages : en
Pages : 492
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Book Description
Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract. It will be useful to investigators in the field of pulmonary toxicology and immunotoxicology, and to those involved in administration and regulation of matters related to inhaled materials. It can also serve as a textbook for a course in pulmonary immunotoxicology at graduate or advanced undergraduate level. Pulmonary Immunotoxicology comprises four sections. The first provides basic background concepts essential for understanding pulmonary immunotoxicology, including discussions of the normal structure and function of the respiratory system, its basic immunology, and the manner by which inhaled particles and gases are removed from the air and deposited upon respiratory tract surfaces. The second section provides an overview of the major types of pathological consequences which can arise from immunomodulation within the respiratory tract, including hypersensitivity and asthma, inflammation and fibrosis, as well as immunosuppression and autoimmunity. The third section, which comprises the largest portion of the book, deals specifically with major classes of airborne agents that are known to alter the immune function of the respiratory tract. These are arranged into major classes: organic agents, metals, gases, particles, biologics, and complex mixtures. The fourth and final section of the book explores the area of risk assessment, including discussions of the basic concepts of risk assessment as they apply specifically to immunotoxicologic effects upon the lungs, and the use of biomarkers as indices of potential pulmonary immunotoxic responses to inhaled materials.
Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1532
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Book Description
