Author: J. P. Bolam
Publisher: Oxford University Press, USA
ISBN:
Category : Literary Criticism
Languages : en
Pages : 302
Book Description
A practical guide to the most important and up-to-date techniques used in experimental neuroanatomy. It should be of use to anyone wishing to apply these important techniques, especially neuroscientists and neuroanatomists.
Experimental Neuroanatomy
Author: J. P. Bolam
Publisher: Oxford University Press, USA
ISBN:
Category : Literary Criticism
Languages : en
Pages : 302
Book Description
A practical guide to the most important and up-to-date techniques used in experimental neuroanatomy. It should be of use to anyone wishing to apply these important techniques, especially neuroscientists and neuroanatomists.
Publisher: Oxford University Press, USA
ISBN:
Category : Literary Criticism
Languages : en
Pages : 302
Book Description
A practical guide to the most important and up-to-date techniques used in experimental neuroanatomy. It should be of use to anyone wishing to apply these important techniques, especially neuroscientists and neuroanatomists.
Electron Microscopy of Axon Degeneration
Author: John F. Alksne
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 38
Book Description
Experimental methods for the mapping of nervous pathways are based partlyon the study of retrograde processes in the perikaryon, partlyon the demonstration of degenerative processes along the peripheral part of a transected axon. For this purpose, the Marchi method by which a selective staining of degenerating myelin is obtained has been extensively used. However, when this method is used the non-myelinated terminals of the transected axons are not stained. The introduction, about two decades ago, of silver impregnation as a means of tracing degenerating axons (especially the Glees and Nauta methods) by which also terminal boutons can be demonstrated, led therefore to revolutionary progress in the investigation of interneuronal connections. Notwithstanding, there are weH known difficulties involved in this kind of research. The capriciousness of the silver methods not seldom results in failure of impregnation with loss of valuable experimental animals. But even when well impregnated sections are used, other fundamental difficulties exist. One of the major problems is to prove beyond doubt that the impregnated structures are degenerating boutons and not merely fragments of non-terminal fibres passing the area under examination. Furthermore, only on occasion will silver impregnation permit one to accurately define the specific part of the receiving neuron on which the impregnated fibres end, i. e. , whether the bouton makes contact with soma, dendrite or spine.
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 38
Book Description
Experimental methods for the mapping of nervous pathways are based partlyon the study of retrograde processes in the perikaryon, partlyon the demonstration of degenerative processes along the peripheral part of a transected axon. For this purpose, the Marchi method by which a selective staining of degenerating myelin is obtained has been extensively used. However, when this method is used the non-myelinated terminals of the transected axons are not stained. The introduction, about two decades ago, of silver impregnation as a means of tracing degenerating axons (especially the Glees and Nauta methods) by which also terminal boutons can be demonstrated, led therefore to revolutionary progress in the investigation of interneuronal connections. Notwithstanding, there are weH known difficulties involved in this kind of research. The capriciousness of the silver methods not seldom results in failure of impregnation with loss of valuable experimental animals. But even when well impregnated sections are used, other fundamental difficulties exist. One of the major problems is to prove beyond doubt that the impregnated structures are degenerating boutons and not merely fragments of non-terminal fibres passing the area under examination. Furthermore, only on occasion will silver impregnation permit one to accurately define the specific part of the receiving neuron on which the impregnated fibres end, i. e. , whether the bouton makes contact with soma, dendrite or spine.
The Brain
Author: Charles Watson
Publisher: Academic Press
ISBN: 0080920489
Category : Medical
Languages : en
Pages : 216
Book Description
The authors of the most cited neuroscience publication, The Rat Brain in Stereotaxic Coordinates, have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience. - Based on contemporary neuroscience research rather than old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - The neuroscience of consciousness, memory, emotion, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illustrated with over 130 color photographs and diagrams This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine. - Clearly and concisely written for easy comprehension by beginning students - Based on contemporary neuroscience research rather than the concepts of old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - Discussion of the neuroscience of conscience, memory, cognitive function, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illustrated with over 100 color photographs and diagrams
Publisher: Academic Press
ISBN: 0080920489
Category : Medical
Languages : en
Pages : 216
Book Description
The authors of the most cited neuroscience publication, The Rat Brain in Stereotaxic Coordinates, have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience. - Based on contemporary neuroscience research rather than old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - The neuroscience of consciousness, memory, emotion, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illustrated with over 130 color photographs and diagrams This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine. - Clearly and concisely written for easy comprehension by beginning students - Based on contemporary neuroscience research rather than the concepts of old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - Discussion of the neuroscience of conscience, memory, cognitive function, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illustrated with over 100 color photographs and diagrams
Diffusion MRI
Author: Heidi Johansen-Berg
Publisher: Academic Press
ISBN: 0124055095
Category : Medical
Languages : en
Pages : 627
Book Description
Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. - Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging - Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments - New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain - Provides practical advice on running an experiment - Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience - Full color throughout
Publisher: Academic Press
ISBN: 0124055095
Category : Medical
Languages : en
Pages : 627
Book Description
Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. - Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging - Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments - New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain - Provides practical advice on running an experiment - Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience - Full color throughout
The Neurobiological Basis of Suicide
Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485
Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485
Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Neuroanatomy through Clinical Cases with ebook
Author: Hal Blumenfeld
Publisher: Sinauer
ISBN: 9780878936137
Category : Medical
Languages : en
Pages : 0
Book Description
This book brings a pioneering interactive approach to the teaching of neuroanatomy, using over 100 actual clinical cases and high-quality radiologic images to bring the subject to life. This edition is fully updated with the latest advances and includes several exciting new cases and a 2-year subscription to the interactive eBook.
Publisher: Sinauer
ISBN: 9780878936137
Category : Medical
Languages : en
Pages : 0
Book Description
This book brings a pioneering interactive approach to the teaching of neuroanatomy, using over 100 actual clinical cases and high-quality radiologic images to bring the subject to life. This edition is fully updated with the latest advances and includes several exciting new cases and a 2-year subscription to the interactive eBook.
Human Neuroanatomy
Author: James R. Augustine
Publisher: Academic Press
ISBN: 0120682516
Category : Medical
Languages : en
Pages : 515
Book Description
This textbook provides a thorough and comprehensive overview of the human brain and spinal cord.
Publisher: Academic Press
ISBN: 0120682516
Category : Medical
Languages : en
Pages : 515
Book Description
This textbook provides a thorough and comprehensive overview of the human brain and spinal cord.
Neuroanatomy of Language Regions of the Human Brain
Author: Michael Petrides
Publisher: Academic Press
ISBN: 0124059317
Category : Psychology
Languages : en
Pages : 197
Book Description
Many studies of the neural bases of language processes are now conducted with functional and structural neuroimaging. Research is often compromised because of difficulties in identifying the core structures in the face of the complex morphology of these regions of the brain. Although there are many books on the cognitive aspects of language and also on neurolinguistics and aphasiology, Neuroanatomy of Language Regions of the Human Brain is the first anatomical atlas that focuses on the core regions of the cerebral cortex involved in language processing. This atlas is a richly illustrated guide for scientists interested in the gross morphology of the sulci and gyri of the core language regions, in the cytoarchitecture of the relevant cortical areas, and in the connectivity of these areas. Data from diffusion MRI and resting-state connectivity are integrated iwth critical experimental anatomical data about homologous areas in the macaque monkey to provide the latest information on the connectivity of the language-relevant cortical areas of the brain. Although the anatomical connectivity data from studies on the macaque monkey provide the most detailed information, they are often neglected because of difficulties in interpreting the terminology used and in making the monkey-to-human comparison. This atlas helps investigators interpret this important source of information. Neuroanatomy of Language Regions of the Human Brain will assist investigators of the neural bases of language in increasing the anatomical sophistication of their research adn in evaluating studies of language and the brain. - Abundantly illustrated with photographs, 3-D MRI reconstructions, and sections to represent the morphology of the sulci and gyri in the frontal, temporal, and parietal regions involved in language processing - Photomicrographs showing the cytoarchitecture of cortical areas involved in language processing - Series of coronal, sagittal, and horizontal sections identifying the sulci and gyri to assist language investigators using structural and functional neuroimaging techniques - All images accompanied by brief commentaries to help users navigate the complexities of the anatomy - Integration of data from diffusion MRI and resting-state connectivity with critical experimental anatomical data on the connectivity of homologous areas in the macaque monkey
Publisher: Academic Press
ISBN: 0124059317
Category : Psychology
Languages : en
Pages : 197
Book Description
Many studies of the neural bases of language processes are now conducted with functional and structural neuroimaging. Research is often compromised because of difficulties in identifying the core structures in the face of the complex morphology of these regions of the brain. Although there are many books on the cognitive aspects of language and also on neurolinguistics and aphasiology, Neuroanatomy of Language Regions of the Human Brain is the first anatomical atlas that focuses on the core regions of the cerebral cortex involved in language processing. This atlas is a richly illustrated guide for scientists interested in the gross morphology of the sulci and gyri of the core language regions, in the cytoarchitecture of the relevant cortical areas, and in the connectivity of these areas. Data from diffusion MRI and resting-state connectivity are integrated iwth critical experimental anatomical data about homologous areas in the macaque monkey to provide the latest information on the connectivity of the language-relevant cortical areas of the brain. Although the anatomical connectivity data from studies on the macaque monkey provide the most detailed information, they are often neglected because of difficulties in interpreting the terminology used and in making the monkey-to-human comparison. This atlas helps investigators interpret this important source of information. Neuroanatomy of Language Regions of the Human Brain will assist investigators of the neural bases of language in increasing the anatomical sophistication of their research adn in evaluating studies of language and the brain. - Abundantly illustrated with photographs, 3-D MRI reconstructions, and sections to represent the morphology of the sulci and gyri in the frontal, temporal, and parietal regions involved in language processing - Photomicrographs showing the cytoarchitecture of cortical areas involved in language processing - Series of coronal, sagittal, and horizontal sections identifying the sulci and gyri to assist language investigators using structural and functional neuroimaging techniques - All images accompanied by brief commentaries to help users navigate the complexities of the anatomy - Integration of data from diffusion MRI and resting-state connectivity with critical experimental anatomical data on the connectivity of homologous areas in the macaque monkey
The Emotional Brain
Author: P.V. Simonov
Publisher: Springer Science & Business Media
ISBN: 148990591X
Category : Psychology
Languages : en
Pages : 274
Book Description
This book deals with the results of theoretical and ex perimental studies of the emotions which my colleagues and I carried out over the last two decades. An interest in the psychology of emotions prompted us to undertake an analysis of the creative legacy of K. S. Stanislavsky. A result of this analysis was the book, The Method of K. s. StanisZavsky and the PhysioZogy of Emotions, written in 1955-1956 and published by the Academy of Sciences of the USSR in 1962. I am grateful to the first reader and critic of the manuscript, Leon Abgarovich Orbeli. In 1960, having transferred to the Institute of Higher Nervous Activ ity and Neurophysiology of the Academy of Sciences of the USSR, I had the opportunity to conduct experiments on prob lems that had interested me for a long time. In close scien tific association with Peter Mikhailovich Ershov, director and teacher of theater, I began a systematic study of the in voluntary and electrophysiological shifts in actors during voluntary production of various emotional states. Here comparatively quickly we became convinced that the fruitfulness of such studies rests on an absence of any kind of developed, systematic, and sound generaZ theory of the emotions of man and the higher mammals. We will illustrate our difficulties if only with one example. We had frequently read of the so-called "emotional memory.
Publisher: Springer Science & Business Media
ISBN: 148990591X
Category : Psychology
Languages : en
Pages : 274
Book Description
This book deals with the results of theoretical and ex perimental studies of the emotions which my colleagues and I carried out over the last two decades. An interest in the psychology of emotions prompted us to undertake an analysis of the creative legacy of K. S. Stanislavsky. A result of this analysis was the book, The Method of K. s. StanisZavsky and the PhysioZogy of Emotions, written in 1955-1956 and published by the Academy of Sciences of the USSR in 1962. I am grateful to the first reader and critic of the manuscript, Leon Abgarovich Orbeli. In 1960, having transferred to the Institute of Higher Nervous Activ ity and Neurophysiology of the Academy of Sciences of the USSR, I had the opportunity to conduct experiments on prob lems that had interested me for a long time. In close scien tific association with Peter Mikhailovich Ershov, director and teacher of theater, I began a systematic study of the in voluntary and electrophysiological shifts in actors during voluntary production of various emotional states. Here comparatively quickly we became convinced that the fruitfulness of such studies rests on an absence of any kind of developed, systematic, and sound generaZ theory of the emotions of man and the higher mammals. We will illustrate our difficulties if only with one example. We had frequently read of the so-called "emotional memory.
Neuroanatomy and Pathology of Sporadic Alzheimer's Disease
Author: Heiko Braak
Publisher: Springer
ISBN: 3319126792
Category : Medical
Languages : en
Pages : 168
Book Description
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Publisher: Springer
ISBN: 3319126792
Category : Medical
Languages : en
Pages : 168
Book Description
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail