Evolutionary Mechanisms of Infectious Diseases PDF Download
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Author: Yufeng Wang
Publisher: Frontiers Media SA
ISBN: 2889669858
Category : Science
Languages : en
Pages : 258
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Book Description
Author: Yufeng Wang
Publisher: Frontiers Media SA
ISBN: 2889669858
Category : Science
Languages : en
Pages : 258
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Book Description
Author: Jianying Gu
Publisher: Frontiers Media SA
ISBN: 2832521924
Category : Science
Languages : en
Pages : 135
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Book Description
Author: Michel Tibayrenc
Publisher: Elsevier
ISBN: 0443288194
Category : Medical
Languages : en
Pages : 1002
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Book Description
Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters
Author: Steven A. Frank
Publisher: Princeton University Press
ISBN: 9780691095950
Category : Medical
Languages : en
Pages : 364
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Author: Steven A. Frank
Publisher: Princeton University Press
ISBN: 0691220166
Category : Medical
Languages : en
Pages : 360
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Book Description
From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive synthesis of parasite variation at the molecular, population, and evolutionary levels, this book is essential reading for students and researchers throughout biology and biomedicine. The author uses an evolutionary perspective to meld the terms and findings of molecular biology, immunology, pathogen biology, and population dynamics. This multidisciplinary approach offers newcomers a readable introduction while giving specialists an invaluable guide to allied subjects. Every aspect of the immune response is presented in the functional context of parasite recognition and defense--an emphasis that gives structure to a tremendous amount of data and brings into sharp focus the great complexity of immunology. The problems that end each chapter set the challenge for future research, and the text includes extensive discussion of HIV, influenza, foot-and-mouth disease, and many other pathogens. This is the only book that treats in an integrated way all factors affecting variation in infectious disease. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For molecular biologists, immunologists, and evolutionary biologists, this book provides new insight into infectious agents, immunity, and the evolution of infectious disease.
Author: Nicole Nova
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
SARS. Ebola. Zika. COVID-19. The majority of all new infectious diseases discovered in the last decades are transmitted from animals to humans. More and more diseases have "spilled over" from wildlife to humans and escalated into pandemics, largely due to anthropogenic activities and global change, including climate change and land use change. Emerging diseases in wildlife can spill over from one species to another, decimating many vulnerable species. However, because human and wildlife systems are so complex, we still lack a clear understanding of the mechanisms driving disease emergence. My dissertation fills some critical gaps in our understanding of the ecological and evolutionary drivers of infectious diseases within and across species. In Chapter 1, I showed how temperature, rainfall and susceptible population size (ecological drivers) affect the (re)emerging mosquito-borne disease dengue. I used a data-driven approach for inferring causal relationships in nonlinear systems and demonstrated that suitable climate can only promote epidemics when the susceptible population is sufficiently large. In Chapter 2, I uncovered ecological and evolutionary drivers of pathogen sharing between different species using datasets of organisms and their pathogens, and their ecological and phylogenetic similarities, to understand how pathogens have adapted to multiple organisms. Here, I quantified the relative importance between ecological and evolutionary factors for predicting pathogen sharing by taxonomic level. Finally, Chapter 3 highlights a wildlife disease case study using genomic analyses of canine distemper virus (CDV) sampled from different carnivores in Alaska and Yellowstone to understand how viruses evolve in wildlife and what disease dynamics they cause. All these findings will help facilitate more effective preventative disease management strategies to improve human and animal health. In sum, my dissertation will help bridge the knowledge gap between ecological and evolutionary drivers of infectious diseases to better understand spillover and subsequent outbreaks. My research will help lay the foundation for future interdisciplinary studies in disease ecology and molecular evolution and will improve the effectiveness of both public health strategies and wildlife conservation.
Author: Paul W. Ewald
Publisher: Oxford University Press, USA
ISBN: 019506058X
Category : Communicable diseases
Languages : en
Pages : 309
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Book Description
Interventions to control diseases don't simply hinder their spread but can cause pathogens and the diseases they engender to evolve into more benign forms. In fact, the union of health science with evolutionary biology offers an entirely new dimension to policy making, as the possibility of determining the future course of many diseases becomes a reality
Author: James Thomas Charles Nash
Publisher:
ISBN:
Category : Diseases
Languages : en
Pages : 90
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Book Description
Author: Stephen C. Stearns
Publisher: Oxford University Press
ISBN: 0199207453
Category : Health & Fitness
Languages : en
Pages : 397
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Book Description
This work explores and analyses the ways in which our ancient genes contend with, and influence, modern human life. It offers coverage of the points of contact between evolutionary biology and medical science.
Author: Marta Wayne
Publisher: OUP Oxford
ISBN: 0191002836
Category : Medical
Languages : en
Pages : 138
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Book Description
As doctors and biologists have learned, to their dismay, infectious disease is a moving target: new diseases emerge every year, old diseases evolve into new forms, and ecological and socioeconomic upheavals change the transmission pathways by which disease spread. By taking an approach focused on the general evolutionary and ecological dynamics of disease, this Very Short Introduction provides a general conceptual framework for thinking about disease. Ecology and evolution provide the keys to answering the 'where', 'why', 'how', and 'what' questions about any particular infectious disease: where did it come from? How is it transmitted from one person to another, and why are some individuals more susceptible than others? What biochemical, ecological, and evolutionary strategies can be used to combat the disease? Is it more effective to block transmission at the population level, or to block infection at the individual level? Through a series of case studies, Benjamin Bolker and Marta L. Wayne introduce the major ideas of infectious disease in a clear and thoughtful way, emphasising the general principles of infection, the management of outbreaks, and the evolutionary and ecological approaches that are now central to much research about infectious disease. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
