Evaluation of the Odds Ratio as an Estimator of Vaccine E PDF Download
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Author: MICHAEL S. MANNO
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: MICHAEL S. MANNO
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309044995
Category : Medical
Languages : en
Pages : 382
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Book Description
Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.
Author: Ronald Christensen
Publisher: CRC Press
ISBN: 1439803552
Category : Mathematics
Languages : en
Pages : 518
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Book Description
Emphasizing the use of WinBUGS and R to analyze real data, Bayesian Ideas and Data Analysis: An Introduction for Scientists and Statisticians presents statistical tools to address scientific questions. It highlights foundational issues in statistics, the importance of making accurate predictions, and the need for scientists and statisticians to collaborate in analyzing data. The WinBUGS code provided offers a convenient platform to model and analyze a wide range of data. The first five chapters of the book contain core material that spans basic Bayesian ideas, calculations, and inference, including modeling one and two sample data from traditional sampling models. The text then covers Monte Carlo methods, such as Markov chain Monte Carlo (MCMC) simulation. After discussing linear structures in regression, it presents binomial regression, normal regression, analysis of variance, and Poisson regression, before extending these methods to handle correlated data. The authors also examine survival analysis and binary diagnostic testing. A complementary chapter on diagnostic testing for continuous outcomes is available on the book’s website. The last chapter on nonparametric inference explores density estimation and flexible regression modeling of mean functions. The appropriate statistical analysis of data involves a collaborative effort between scientists and statisticians. Exemplifying this approach, Bayesian Ideas and Data Analysis focuses on the necessary tools and concepts for modeling and analyzing scientific data. Data sets and codes are provided on a supplemental website.
Author: M. Elizabeth Halloran
Publisher: Springer Science & Business Media
ISBN: 0387686363
Category : Medical
Languages : en
Pages : 390
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Book Description
As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.
Author: Maura E. Stokes
Publisher: SAS Institute
ISBN: 1612900909
Category : Computers
Languages : en
Pages : 589
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Book Description
Statisticians and researchers will find Categorical Data Analysis Using SAS, Third Edition, by Maura Stokes, Charles Davis, and Gary Koch, to be a useful discussion of categorical data analysis techniques as well as an invaluable aid in applying these methods with SAS. Practical examples from a broad range of applications illustrate the use of the FREQ, LOGISTIC, GENMOD, NPAR1WAY, and CATMOD procedures in a variety of analyses. Topics discussed include assessing association in contingency tables and sets of tables, logistic regression and conditional logistic regression, weighted least squares modeling, repeated measurements analyses, loglinear models, generalized estimating equations, and bioassay analysis. The third edition updates the use of SAS/STAT software to SAS/STAT 12.1 and incorporates ODS Graphics. Many additional SAS statements and options are employed, and graphs such as effect plots, odds ratio plots, regression diagnostic plots, and agreement plots are discussed. The material has also been revised and reorganized to reflect the evolution of categorical data analysis strategies. Additional techniques include such topics as exact Poisson regression, partial proportional odds models, Newcombe confidence intervals, incidence density ratios, and so on. This book is part of the SAS Press program.
Author: Christopher R. Bilder
Publisher: CRC Press
ISBN: 1040087744
Category : Mathematics
Languages : en
Pages : 706
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Book Description
Analysis of Categorical Data with R, Second Edition presents a modern account of categorical data analysis using the R software environment. It covers recent techniques of model building and assessment for binary, multicategory, and count response variables and discusses fundamentals, such as odds ratio and probability estimation. The authors give detailed advice and guidelines on which procedures to use and why to use them. The second edition is a substantial update of the first based on the authors’ experiences of teaching from the book for nearly a decade. The book is organized as before, but with new content throughout, and there are two new substantive topics in the advanced topics chapter—group testing and splines. The computing has been completely updated, with the "emmeans" package now integrated into the book. The examples have also been updated, notably to include new examples based on COVID-19, and there are more than 90 new exercises in the book. The solutions manual and teaching videos have also been updated. Features: Requires no prior experience with R, and offers an introduction to the essential features and functions of R Includes numerous examples from medicine, psychology, sports, ecology, and many other areas Integrates extensive R code and output Graphically demonstrates many of the features and properties of various analysis methods Offers a substantial number of exercises in all chapters, enabling use as a course text or for self-study Supplemented by a website with data sets, code, and teaching videos Analysis of Categorical Data with R, Second Edition is primarily designed for a course on categorical data analysis taught at the advanced undergraduate or graduate level. Such a course could be taught in a statistics or biostatistics department, or within mathematics, psychology, social science, ecology, or another quantitative discipline. It could also be used by a self-learner and would make an ideal reference for a researcher from any discipline where categorical data arise.
Author: Les Irwig
Publisher: Judy Irwig
ISBN: 1905140177
Category : Health & Fitness
Languages : en
Pages : 255
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Book Description
Every day we make decisions about our health - some big and some small. What we eat, how we live and even where we live can affect our health. But how can we be sure that the advice we are given about these important matters is right for us? This book will provide you with the right tools for assessing health advice.
Author: Sarah S. Long
Publisher: Elsevier Health Sciences
ISBN: 1455739855
Category : Medical
Languages : en
Pages : 2511
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Book Description
Principles and Practice of Pediatric Infectious Disease provides the comprehensive and actionable coverage you need to understand, diagnose, and manage the ever-changing, high-risk clinical problems caused by pediatric infectious diseases. With new chapters, expanded and updated coverage, and increased worldwide perspectives, this authoritative medical reference offers the latest need-to-know information in an easily-accessible, high-yield format for quick answers and fast, effective intervention! Spend less time searching thanks to a consistent, easily-accessible format featuring revised high-yield information boxes, highlighted key points, and an abundance of detailed illustrations and at-a-glance tables. Be prepared for the unexpected! A veritable "who's who" of global authorities provides practical knowledge to effectively diagnose and manage almost any infectious disease you may encounter. Quickly look up the answers you need by clinical presentation, pathogen, or type of host. Get expanded coverage for all types of infectious diseases including new chapters on infection related to pets and exotic animals, and tickborne infections. Apply the latest recommendations and treatments for emerging and re-emerging diseases including the H1N1 virus.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309214351
Category : Medical
Languages : en
Pages : 894
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Book Description
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
