Etiology of Parkinson's Disease PDF Download
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Author: Jonas H. Ellenberg
Publisher: CRC Press
ISBN: 9780824788230
Category : Medical
Languages : en
Pages : 600
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Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Author: Rodrigo Franco
Publisher: Royal Society of Chemistry
ISBN: 1782621881
Category : Medical
Languages : en
Pages : 537
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Book Description
Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress can be defined as an imbalance between the production of reactive species and the ability to detoxify them and their intermediates or by-products. Oxidative damage to lipids, proteins, and DNA has been detected in autopsies from individuals with Parkinson’s Disease and so links can be made between oxidative stress and Parkinson’s Disease pathogenesis. This book provides a thorough review of the mechanisms by which oxidative stress and redox signalling mediate Parkinson’s Disease. Opening chapters bring readers up to speed on basic knowledge regarding oxidative stress and redox signalling, Parkinson’s Disease, and neurodegeneration before the latest advances in this field are explored in detail. Topics covered in the following chapters include the role of mitochondria, dopamine metabolism, metal homeostasis, inflammation, DNA-damage and thiol-signalling. The role of genetics and gene-environment interactions are also explored before final chapters discuss the identification of potential biomarkers for diagnosis and disease progression and the future of redox/antioxidant based therapeutics. Written by recognized experts in the field, this book will be a valuable source of information for postgraduate students and academics, clinicians, toxicologists and risk assessment groups. Importantly, it presents the current research that might later lead to redox or antioxidant – based therapeutics for Parkinson’s disease.
Author: Jonas H. Ellenberg
Publisher: CRC Press
ISBN: 9780824788230
Category : Medical
Languages : en
Pages : 600
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Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Author: James Parkinson
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 86
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Book Description
Author: Anthony Schapira
Publisher: John Wiley & Sons
ISBN: 0470672684
Category : Medical
Languages : en
Pages : 344
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Book Description
This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors
Author: Cristian Falup-Pecurariu
Publisher: Springer
ISBN: 3709116287
Category : Medical
Languages : en
Pages : 444
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Book Description
This book offers a comprehensive approach to the wide range of movement disorders, an important specialty in the field of neurology, guiding readers from the phenomenology to diagnosis and management. Reflecting the latest developments in the field, it offers a unique summary of this dynamic area by pursuing a uniform approach to movement disorders curricula. Divided into three parts, Movement Disorders Curricula provides an authoritative overview of this growing branch of neurology. The first part presents the basic elements of movement disorders, including descriptions of the anatomy and physiology of the basal ganglia. It also features sections on clinical trials for movement disorders, practical skills, and rating scales. The second and third part examine in detail hypokinetic and hyperkinetic movement disorders, respectively. Equipping readers with the practical and research skills needed in the movement disorders field, the book offers a valuable tool to help them prepare for board examinations on general neurology, as well as for fellowships in movement disorders.
Author: Joseph Jankovic
Publisher: Elsevier Health Sciences
ISBN: 1437737706
Category : Medical
Languages : en
Pages : 557
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Book Description
Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.
Author: Robert R. Goodman
Publisher: Springer
ISBN: 9783319236926
Category : Medical
Languages : en
Pages : 0
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Book Description
Deep brain stimulation for the treatment of patients with Parkinson’s disease was introduced in the 1990s. Initially performed only at academic centers, over the past decade it has become a widespread surgical procedure. A variety of surgical techniques are employed and innovations are introduced frequently. This book is an ideal source of information for the many practicing neurosurgeons who did not learn this surgery during their training but would now like to add it to their practice, as well as an excellent update on exciting new developments in surgery for Parkinson’s disease. This book is designed to provide practicing neurosurgeons with current knowledge on the practical aspects of surgical treatment of patients with Parkinson’s disease. It explains how to identify surgical candidates and determine the optimal surgery, describes the various surgical techniques that are currently employed, and offers insights into how to optimize deep brain stimulation therapy after implantation. The keys to avoidance of surgical complications are carefully elucidated. In addition, an overview is provided of potential advances on the near-term horizon, including closed-loop deep brain stimulation, gene therapy, and optogenetics. All topics are covered by experienced Parkinson’s disease surgeons, in a concise and digestable format. The book will be an ideal source of information for the many practicing neurosurgeons who would like to add deep brain stimulation to their practice, as well as an excellent update on new developments in surgery for Parkinson’s disease.
Author: Jolyon Meara
Publisher: Cambridge University Press
ISBN: 0521628849
Category : Medical
Languages : en
Pages : 265
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Book Description
This book covers the clinical features, diagnosis and management of Parkinson's disease in elderly people.
Author: National Institute of Neurological and Communicative Disorders and Stroke
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 20
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Book Description
Author: Carol Brayne
Publisher:
ISBN: 019874949X
Category : Medical
Languages : en
Pages : 513
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Book Description
Neurologic and neuropsychiatric disorders are of great importance to societies and they also raise special considerations in epidemiological research methodology. Not only do neurologic and neuropsychiatric disorders form a major group of disorders associated with ageing populations, but those disorders that occur in earlier life can be associated with severe individual, family, and societal distress and burden. The inter-relationship of syndromes and disorders is a topic of major interest and growing biological insights across psychiatry and neurology. This includes not only overlaps in neurodegenerative syndromes but also those related to other systems such as metabolic, inflammatory, immune and vascular disorders. Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neurologic and Neuropsychiatric Epidemiology is designed to focus on the overlaps and inter-relationships between neuro-epidemiological disorders, as well as on ways to harmonise large cohort studies to maximise opportunities for determining causes related to rarer disorders. Divided into three main parts, the book covers 1) the principles of neurologic and neuropsychiatric epidemiology; 2) specific neuropsychiatric disorders and their inter-relationships and 3) the implications of neuro-epidemiologic research for patient populations and current medical practice. This comprehensive work serves as an invaluable reference to current neuro-epidemiological methods for neurologists, psychiatrists, and senior trainees in those disciplines, as well as public health practitioners and students with an interest in neurology and neuropsychiatry.
