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Author: Christian Behl
Publisher: Springer Science & Business Media
ISBN: 3709161894
Category : Medical
Languages : en
Pages : 256
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Book Description
It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.
Author: Christian Behl
Publisher: Springer Science & Business Media
ISBN: 3709161894
Category : Medical
Languages : en
Pages : 256
Get Book Here
Book Description
It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.
Author: Christian Behl
Publisher:
ISBN: 9783709161906
Category :
Languages : en
Pages : 252
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Book Description
Author: M.A. Hofman
Publisher: Elsevier
ISBN: 008049773X
Category : Medical
Languages : en
Pages : 497
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Book Description
In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.
Author: Niels Bergemann
Publisher: Springer Science & Business Media
ISBN: 9783211404850
Category : Medical
Languages : en
Pages : 316
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Book Description
A number of studies, mostly focusing on estrogen replacement therapy in women, have reported beneficial actions of these hormones on various neurobiological and neuropathological parameters in health and disease. Recent research has focused on gender differences and there is increasing evidence that estrogens exert protective effects in schizophrenia. Hormonal fluctuations or lack of estrogen may increase the risk of depression among vulnerable women. Treatment of depression with estrogen may stabilize and restore disrupted homeostasis – as during post-partum, premenstrual, or perimenopausal conditions – and act as a psychomodulator to offset vulnerability to dysphoric mood when estrogen levels are significantly decreased, as in the case of postmenopausal women. Studies on the effect of estrogens on Alzheimer’s Disease are still rather controversial, they do, however, facilitate the hypothesis that estrogens may have a modifying effect on the onset and course of AD, at least in subgroups of patients.
Author: Annette Schaub
Publisher: Springer Science & Business Media
ISBN: 3709161487
Category : Medical
Languages : en
Pages : 300
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Book Description
This book is dedicated to the memory of Michael J. Goldstein, one of the pioneers in psychosocial intervention in psychiatry. The structure of this book follows Goldstein footsteps in this domain and is subdivided into family factors as well as intervention strategies for severe mental illness. Recent research on high expressed emotion (HEE) in schizophrenia (e.g., early psychosis) and borderline disorder, patients' perspectives of HEE as well as other variables predictive for relapse in recent-onset schizophrenia are covered in this book. Family treatment strategies in schizophrenia, depression, bipolar disorder, substance use disorders and illness management programs as well as pharmacological treatment strategies are illustrate and current studies presented.
Author: Mohammad Resa Nowrousian
Publisher: Springer Science & Business Media
ISBN: 3709176581
Category : Medical
Languages : en
Pages : 524
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Book Description
Anemia is a frequent complication of cancer and its treatment. A number of clinical studies shows that the impact of anemia is much greater than previously thought. Beyond clinical symptoms, anemia significantly impairs physical and metabolic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. In this book, written by a group of outstanding international experts, the current knowledge on anemia in cancer and its treatment with rhEPO is presented. Future developments are also discussed. Based on a broad spectrum of topics, the book describes the scientific and clinical aspects of anemia in various fields of oncology and gives diagnostic and therapeutic recommendations on when and how to use rhEPO.
Author: Heinz Häfner
Publisher: Springer Science & Business Media
ISBN: 3642575161
Category : Psychology
Languages : en
Pages : 352
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Book Description
H. HAFNER Schizophrenia Research Unit, Central Institute of Mental Health, Mannheim, Germany The present volume contains the lectures and invited discussions of the sympo sium on "Risk and protective factors in schizophrenia - towards a conceptual model of the disease process", which was held at the International Science Forum of the University of Heidelberg from October 25 to 27, 200l. They are supple mented by a "Summary and outlook", in which Peter Jones gives a brief overview of the results and perspectives featured in the presentations and discussions. The contributions and discussions reflect the open-minded and creative atmosphere at the meeting. The systematically structured program of the symposium continued the tradition of the Search for the Causes of Schizophrenia symposia, which were th started in 1986 on the occasion of the 600 anniversary of the University of Hei delberg and which are co-organized with Prof. Wagner Farid Gattaz/Sao Paulo. The aim of these symposia and their proceedings volumes [6,8-10] has been to reflect the state of the art in schizophrenia research at their time, and they have successfully done so. In contrast, the present symposium pursued a more lim ited objective and was of a different type. It brought together, around a large table at the International Science Forum in Heidelberg, 22 invited speakers and dis cussants and an equal number of young scientists working in the research fields in question, who were thus given an opportunity to listen and to participate.
Author: Christian Behl
Publisher: Springer Science & Business Media
ISBN: 9783211835395
Category : Medical
Languages : en
Pages : 256
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Book Description
It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.
Author: Christian Alzheimer
Publisher: Springer Science & Business Media
ISBN: 1461501237
Category : Medical
Languages : en
Pages : 507
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Book Description
Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases. This book brings together leading experts from neurobiology, neurophysiology, neuropharmacology, neuroimmunology and clinical neuroscience to highlight the most recent milestones in this rapidly evolving field. The book will serve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies.
Author: Rose Arny
Publisher:
ISBN:
Category : American literature
Languages : en
Pages : 1736
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Book Description
