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Author: W. R. Miller
Publisher: Landes Bioscience
ISBN:
Category : Breast
Languages : en
Pages : 234
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Book Description
Author: W. R. Miller
Publisher: Landes Bioscience
ISBN:
Category : Breast
Languages : en
Pages : 234
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Book Description
Author: Xiaoting Zhang
Publisher: Humana Press
ISBN: 9783030075934
Category :
Languages : en
Pages : 432
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Book Description
The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.
Author: William L. McGuire
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 320
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Book Description
Author: Fritz F. Parl
Publisher: IOS Press
ISBN: 9780967335544
Category : Breast
Languages : en
Pages : 280
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Book Description
Estrogens have been implicated to play a role in the development of breast cancer. The purpose of this book is to provide a comprehensive analysis of experimental, clinical and epidemiological evidence in support of the carcinogenicity of estrogens.
Author: Carol Tavris
Publisher: Hachette UK
ISBN: 0316481181
Category : Health & Fitness
Languages : en
Pages : 187
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Book Description
A compelling, “fascinating” (Robert Cialdini) defense of hormone replacement therapy, exposing the faulty science behind its fall from prominence and giving women the evidence they need to make informed decisions about their health. Now fully revised and updated. "Estrogen Matters was my antidote to the misinformation surrounding menopause. This book should be the bible for every single person going through menopause.”―Naomi Watts For years, hormone replacement therapy (HRT) was the medically approved way to alleviate menopausal symptoms (ranging from hot flushes to brain fog) and reduce the risk of heart disease, Alzheimer's, and osteoporosis. But when a large study by the Women's Health Initiative (WHI) announced, with national fanfare, that women taking HRT had an increased risk of breast cancer, women were scared off, and the treatment was abandoned. Now, Dr. Bluming, a medical oncologist, and Dr. Tavris, a social psychologist, reveal the true story of the WHI’s efforts to distort their data to exaggerate unsupported claims of estrogen’s harms. Important updates in this edition include: Evidence that demolishes the WHI’s claim that HRT causes breast cancer. A list of the WHI’s retractions of their original scare stories. Updated findings on estrogen’s benefits on heart, brain, bones, and longevity. A critical review of the alternative products and medications being marketed to treat symptoms of menopause. A sobering and revelatory read, Estrogen Matters sets the record straight on estrogen’s benefits, providing a light to guide women through this inevitable phase of life.
Author: Malcolm C. Pike
Publisher:
ISBN:
Category : Breast
Languages : en
Pages : 520
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Book Description
Author: John E. Niederhuber
Publisher: Decker
ISBN:
Category : Medical
Languages : en
Pages : 696
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Book Description
A multidisciplinary reference work in oncology providing discussions of the biology, diagnosis and treatment of a broad range of clinical cancer problems. The book presents an integrated approach to the treatment of patients with cancer covering medical oncology, radiation and more.
Author: Tobias Pischon
Publisher: Springer
ISBN: 3319425420
Category : Medical
Languages : en
Pages : 258
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Book Description
This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.
Author: Virgil Craig Jordan
Publisher: Univ of Wisconsin Press
ISBN: 9780299104801
Category : Breast
Languages : en
Pages : 564
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Book Description
This book marks one of the achievements of the "Estrogen and Antiestrogen Action: Basic and Clinical Aspects" Wisconsin Clinical Cancer Center conference in June 1984. It is not intended to be a recount of the meeting proceedings but is, rather, a historical review of the development of this field of endeavor during the past 30 years. The chapters have been written by many of the leading experts in the field who were asked to recount the development of a particular area or laboratory idea in which they had been personally involved. The book is intended to provide both scientists and clinicians with a single-volume overview of both the basic principles of hormonal control of breast cancer and the recent clinical results from cooperative groups around the world.
Author: Carol Ann Rinzler
Publisher: Hunter House
ISBN:
Category : Health & Fitness
Languages : en
Pages : 244
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Book Description
A cautionary tale about American medicine's experimentation with female hormones, this balanced book chronicles the 60-year attempt to "cure" menopause with estrogen and the 40-year history of chemical contraception, weighing the pros and cons of estrogen use and allowing women to make informed decisions about their bodies.
