Essentials of Pharmacodynamics and Drug Action PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Essentials of Pharmacodynamics and Drug Action PDF full book. Access full book title Essentials of Pharmacodynamics and Drug Action by Raja Chakraverty. Download full books in PDF and EPUB format.
Author: Raja Chakraverty
Publisher: Springer
ISBN: 9789819727759
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
The book provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment. Readers will gain insights into drugs that target the autonomic nervous system, influencing functions beyond voluntary control, and drugs that act on the central nervous system, impacting neurological processes. Additionally, the book examines medications affecting renal and cardiovascular functions, playing a significant role in maintaining homeostasis. Moreover, it explores the realm of drugs influencing gastrointestinal function, essential for digestive health. Furthermore, the book covers pharmacotherapy for microbial diseases, addressing the challenge of infectious agents and their treatment. It also investigates hormones and hormone antagonists, pivotal in regulating various physiological processes. Lastly, it provides a comprehensive understanding of drugs used for immunomodulation, which plays a crucial role in enhancing or suppressing the immune system. The book serves as a resource for students, researchers, and healthcare professionals seeking a deep understanding of drug interactions, therapeutic applications, and cutting-edge approaches in pharmacology.
Author: Raja Chakraverty
Publisher: Springer
ISBN: 9789819727759
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
The book provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment. Readers will gain insights into drugs that target the autonomic nervous system, influencing functions beyond voluntary control, and drugs that act on the central nervous system, impacting neurological processes. Additionally, the book examines medications affecting renal and cardiovascular functions, playing a significant role in maintaining homeostasis. Moreover, it explores the realm of drugs influencing gastrointestinal function, essential for digestive health. Furthermore, the book covers pharmacotherapy for microbial diseases, addressing the challenge of infectious agents and their treatment. It also investigates hormones and hormone antagonists, pivotal in regulating various physiological processes. Lastly, it provides a comprehensive understanding of drugs used for immunomodulation, which plays a crucial role in enhancing or suppressing the immune system. The book serves as a resource for students, researchers, and healthcare professionals seeking a deep understanding of drug interactions, therapeutic applications, and cutting-edge approaches in pharmacology.
Author: Sara E. Rosenbaum
Publisher: John Wiley & Sons
ISBN: 1119143152
Category : Medical
Languages : en
Pages : 589
Get Book Here
Book Description
Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out ... and also for use as a reference book ...." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD .... “ (British Toxicology Society Newsletter)
Author: Daan Venter
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 129
Get Book Here
Book Description
Author: Thomas N. Tozer
Publisher: LWW
ISBN: 9781451194425
Category : Drugs
Languages : en
Pages : 0
Get Book Here
Book Description
Master the fundamentals of pharmacokinetics and pharmacodynamics with the new edition of this unique text. Essentials of Pharmacokinetics and pharmacodynamics, Second Edition (formerly An Introduction to Pharmacokinetics and Pharmacodynamics), contains must-know content for students of pharmacy and medicine, people engaged in drug development and those working in drug regulatory agencies, as well as any health care professional who needs to understand the basic principles upon which quantitative decisions in drug therapy are based. This new edition provides essential information on the link between drug exposure within the body to drug response the key quantitative tools and principles of drug therapy you need to know, without extensive mathematics: up-to-date examples of currently prescribed drugs are particularly relevant to contemporary practice, and study problems in every chapter help you master the information in the text. Features more and updated study problems, including many that follow the multiple-choice format used in licensing examinations. Detailed answers are provided in an appendix to assist the reader in learning the material. The content of all chapters has been updated, and more than 60 new and improved illustrations have been added. Offers expanded content on Qualifying Events an Intravenous Bolus, Physiologic and Physicochemical Determinants of Drug Disposition; Quantifying Events Following an Extravascular Dose, and Physiologic and Physicochemical Determinants of Drug Absorption Gives greater emphasis to protein drugs and physiologic concepts, with clearly organized and updated content. Includes practice questions to reinforce your comprehension of the topics. Emphasizes the integration of basic concepts in each chapter, ensuring that the material builds on knowledge from prior chapters and is presented in the clearest way possible. Book jacket.
Author: Gerard Marshall Raj
Publisher: Springer
ISBN: 9789813297814
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.
Author: F S K Barar
Publisher: S. Chand Publishing
ISBN: 8121904447
Category : Medical
Languages : en
Pages : 639
Get Book Here
Book Description
This comprehensive and well-written book presents the fundamental concepts of Pharmacotherapeutics, aiming at the safe and effective use of drugs in the treatment of disease. It is interdisciplinary in its approach and provides a basis for understanding the actions and uses of drugs in man. It is written in a simple and easy-to-understand language. The text is divided into sixteen chapters
Author: Maria A. Hernandez, Ph.D.
Publisher: CRC Press
ISBN: 1351988654
Category : Medical
Languages : en
Pages : 400
Get Book Here
Book Description
Intended for use in an introductory pharmacology course, Basic Pharmacology: Understanding Drug Actions and Reactions provides an in-depth discussion of how to apply the chemical and molecular pharmacology concepts, a discussion students need for more advanced study. The textbook introduces the principles of chemistry and biology necessary to understand drug interactions at the cellular level. The authors highlight chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and elimination. The book begins with a review of chemical principles as they apply to drug molecules, focusing mainly on those for commonly prescribed drugs. The authors use drug structures to illustrate the chemical concepts learned in general and organic chemistry courses. They cover the dynamics of receptors in mediating the pharmacological effects of drugs. They clarify theories, drawn from the scientific literature, which explain drug-receptor interactions and the quantitative relationship between drug binding and its effects at the cellular level. The authors’ extensive use of drug structures for teaching chemical and molecular pharmacology principles, and their emphasis on the relevance of these principles in future professional life makes this book unique. It provides the framework for better understanding of advanced pharmacology and therapeutics topics. Blending medicinal chemistry and pharmacodynamics aspects, this textbook clearly elucidates the essential concepts that form the cornerstone for further work in pharmacology.
Author: Francesco Clementi
Publisher: John Wiley & Sons
ISBN: 1118768574
Category : Medical
Languages : en
Pages : 784
Get Book Here
Book Description
With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Author: Younggil Kwon
Publisher: Springer Science & Business Media
ISBN: 0306468204
Category : Medical
Languages : en
Pages : 302
Get Book Here
Book Description
In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phases, the identifi- tion of the critical PK/PD/DM issues of new compounds plays an essential role in understanding their pharmacological profiles and structure-activity relationships. Owing to recent progress in analytical chemistry, a large number of compounds can be screened for their PK/PD/DM properties within a relatively short period of time. During development phases as well, the toxicology and clinical study designs and trials of a compound should be based on a thorough understanding of its PK/PD/DM properties. During my time as an industrial scientist, I realized that a reference work designed for practical industrial applications of PK/PD/DM could be a very valuable tool for researchers not only in the pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies. This book is designed specifically for industrial scientists, laboratory assistants, and managers who are involved in PK/PD/DM-related areas. It consists of thirteen chapters, each of which deals with a particular PK/PD/DM issue and its industrial applications. Chapters 3 and 12 in particular address recent topics on higher throughput in vivo exposure screening and the prediction of pharmacokinetics in humans, respectively. Chapter 8 covers essential information on drug metabolism for industrial scientists.
Author: Alexander A. Vinks
Publisher: Springer Science & Business Media
ISBN: 0387756132
Category : Medical
Languages : en
Pages : 467
Get Book Here
Book Description
Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.
