Essentials of Biopharmaceutics and Pharmacokinetics - E-Book

Essentials of Biopharmaceutics and Pharmacokinetics - E-Book PDF Author: Ashutosh Kar
Publisher: Elsevier Health Sciences
ISBN: 813123262X
Category : Medical
Languages : en
Pages : 370

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Book Description
Essentials of Biopharmaceutics and Pharmacokinetics Kar’s Essentials of Biopharmaceutics and Pharmacokinetics deals with how a drug exerts its action in the human body through the fundamentals of absorption, distribution, metabolism and excretion. The book adopts a growth-oriented format and design that is developed systematically and methodically. The book interrelates five different sections: Section 1 Biopharmaceutics and Pharmacokinetics: What Do They Mean? Section 2 Biopharmaceutics Section 3 Pharmacokinetics Section 4 Clinical Pharmacokinetics Section 5 Bioavailability and Bioequivalence Each section starts with a basic theory and fields of application, focuses on model-independent pharmacokinetic analyses, expatiates various biopharmaceutical aspects of dosage form and evaluation, provides an altogether new approach in understanding both dosage regimen design and individualization, and explains modification in drug molecules related to the pharmacokinetics. Undoubtedly, the unique blend of fundamental principles and latest breakthroughs in the field will certainly provide sufficient subject matter to the students of pharmacy, pharmacology, medicinal chemistry scientists, who need a simple as well as detailed introduction in theory and application.

Essentials of Biopharmaceutics and Pharmacokinetics - E-Book

Essentials of Biopharmaceutics and Pharmacokinetics - E-Book PDF Author: Ashutosh Kar
Publisher: Elsevier Health Sciences
ISBN: 813123262X
Category : Medical
Languages : en
Pages : 370

Get Book Here

Book Description
Essentials of Biopharmaceutics and Pharmacokinetics Kar’s Essentials of Biopharmaceutics and Pharmacokinetics deals with how a drug exerts its action in the human body through the fundamentals of absorption, distribution, metabolism and excretion. The book adopts a growth-oriented format and design that is developed systematically and methodically. The book interrelates five different sections: Section 1 Biopharmaceutics and Pharmacokinetics: What Do They Mean? Section 2 Biopharmaceutics Section 3 Pharmacokinetics Section 4 Clinical Pharmacokinetics Section 5 Bioavailability and Bioequivalence Each section starts with a basic theory and fields of application, focuses on model-independent pharmacokinetic analyses, expatiates various biopharmaceutical aspects of dosage form and evaluation, provides an altogether new approach in understanding both dosage regimen design and individualization, and explains modification in drug molecules related to the pharmacokinetics. Undoubtedly, the unique blend of fundamental principles and latest breakthroughs in the field will certainly provide sufficient subject matter to the students of pharmacy, pharmacology, medicinal chemistry scientists, who need a simple as well as detailed introduction in theory and application.

Essentials of Biopharmaceutics and Pharmacokinetics for Bpharm, Mpharm and Research Scholars

Essentials of Biopharmaceutics and Pharmacokinetics for Bpharm, Mpharm and Research Scholars PDF Author: A. Kar
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9789388327534
Category : Medical
Languages : en
Pages :

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Book Description
A comprehensive textbook for learning and teaching the fundamentals of biopharmaceutics along with specific focus on pharmacokinetics for BPharm and MPharm students.

Biopharmaceutics and Pharmacokinetics

Biopharmaceutics and Pharmacokinetics PDF Author: J. S. Kulkarni
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9788123913070
Category : Medical
Languages : en
Pages : 301

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Book Description
Biopharmaceutics and Pharmacokinetics deals with what body does to the drug. In this book, along with the fundamentals of absorption, distribution, metabolism and excretion, current topics such as in vitro systems have also been introduced. In case of pharmacokinetics models, authors have tried to keep mathematical part simpler and minimal. This book also introduces "non compartmental models", which are gaining increasing importance in the analysis of pharmacokinetic data. In the chapter "applications of pharamacokinetics", newer concepts such as chronopharmacokinetics have been introduced. Bioequivalence is covered in last two chapters. Besides clinical aspects of bioequivalence, some of the important aspects of bioanalysis have also been introduced. The regulatory aspect of bioequivalence has also been covered. Thus an attempt has been made to cover all the basic aspects of biopharmaceutics and pharmacokinetics in a reader-friendly manner.

A TEXT BOOK OF BIOPHARMACEUTICS AND PHARMACOKINETICS

A TEXT BOOK OF BIOPHARMACEUTICS AND PHARMACOKINETICS PDF Author: Dr. Satyajit Panda, Dr. Chandra Sekhar Barik, Dr. Bhargab Jyoti Sahariah
Publisher: Shashwat Publication
ISBN: 9360877921
Category : Medical
Languages : en
Pages : 279

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Book Description
According to PCI regulations, the book is named "Textbook of Biopharmaceutics and Pharmacokinetics". The authors' original intention for the book was to provide a unified database that would make Biopharmaceutics and Pharmacokinetics easily understood. This book aims to enlighten readers on cutting-edge drug delivery methods and provide guidance to educators and students on the essential ideas of Biopharmaceutics and Pharmacokinetics. The primary goal in writing this textbook was to satisfy students' needs in accordance with PCI regulations by presenting material in an eloquent, summarised way. This book is intended to convey information on Biopharmaceutics and Pharmacokinetics to postgraduate learners, in addition to adhering to the curriculum of PCI's undergraduate pharmacy courses. We guarantee that this book will be highly appreciated by academics, professionals in the field, postgraduate students, and graduates. Nonetheless, recommendations about how to make the text better are welcome and will be duly noted.

Pharmacokinetics: Basics to Applications

Pharmacokinetics: Basics to Applications PDF Author: Biswajit Mukherjee
Publisher: Springer Nature
ISBN: 9811689504
Category : Medical
Languages : en
Pages : 354

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Book Description
This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.

Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics

Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics PDF Author: Panos Macheras
Publisher: Springer Science & Business Media
ISBN: 0387319107
Category : Mathematics
Languages : en
Pages : 446

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Book Description
This book presents a novel modeling approach to biopharamceutics, pharmacokinetics and pharmacodynamic phenomena. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. Throughout, many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.

Essentials of Pharmacokinetics and Pharmacodynamics

Essentials of Pharmacokinetics and Pharmacodynamics PDF Author: Thomas N. Tozer
Publisher: LWW
ISBN: 9781451194425
Category : Drugs
Languages : en
Pages : 0

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Book Description
Master the fundamentals of pharmacokinetics and pharmacodynamics with the new edition of this unique text. Essentials of Pharmacokinetics and pharmacodynamics, Second Edition (formerly An Introduction to Pharmacokinetics and Pharmacodynamics), contains must-know content for students of pharmacy and medicine, people engaged in drug development and those working in drug regulatory agencies, as well as any health care professional who needs to understand the basic principles upon which quantitative decisions in drug therapy are based. This new edition provides essential information on the link between drug exposure within the body to drug response the key quantitative tools and principles of drug therapy you need to know, without extensive mathematics: up-to-date examples of currently prescribed drugs are particularly relevant to contemporary practice, and study problems in every chapter help you master the information in the text. Features more and updated study problems, including many that follow the multiple-choice format used in licensing examinations. Detailed answers are provided in an appendix to assist the reader in learning the material. The content of all chapters has been updated, and more than 60 new and improved illustrations have been added. Offers expanded content on Qualifying Events an Intravenous Bolus, Physiologic and Physicochemical Determinants of Drug Disposition; Quantifying Events Following an Extravascular Dose, and Physiologic and Physicochemical Determinants of Drug Absorption Gives greater emphasis to protein drugs and physiologic concepts, with clearly organized and updated content. Includes practice questions to reinforce your comprehension of the topics. Emphasizes the integration of basic concepts in each chapter, ensuring that the material builds on knowledge from prior chapters and is presented in the clearest way possible. Book jacket.

Biopharmaceutics and Pharmacokinetics

Biopharmaceutics and Pharmacokinetics PDF Author: V. Venkateswarlu
Publisher: Pharmamed Press
ISBN: 9789352300532
Category : Medical
Languages : en
Pages : 530

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Book Description
This book deals with the basics of the two disciplines of biopharmaceutics and pharmacokinetics. Different factors such as biological, physiochemical and formulation that influence the therapeutic efficacy of a drug are covered in biopharmaceutics. The absorption, distribution, metabolism and excretion of drugs are studied under this subject. Salient Features - Basics of biopharmaceutics and pharmacokinetics help to understand the various procedures and advances in drug design, product development, therapeutic drug monitoring, etc. - Pharmacokinetics covers the fundamentals of one compartment open model, multi-compartmental models. One compartment open model is presented in an elaborate manner to make the students familiar with various aspects of pharmacokinetics - Mathematical equations are developed using simple integration and differentiation methods - Practice problems are provided wherever necessary, and a question bank is included at the end of each chapter - Extreme care has been exercised to present the concepts in a simple way Second Edition includes - Application of principles in formulation development in industry for successful bioequivalence studies is included - One chapter on "In-vitro Dissolution Testing" is included to evaluate test formulations to chose right product for bioequivalence studies - A chapter on biostatistics with practice problems is included

Biopharmaceutics and Clinical Pharmacokinetics

Biopharmaceutics and Clinical Pharmacokinetics PDF Author: Notari
Publisher: Routledge
ISBN: 1351463845
Category : Science
Languages : en
Pages : 287

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Book Description
For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.

Basic Pharmacokinetics and Pharmacodynamics

Basic Pharmacokinetics and Pharmacodynamics PDF Author: Sara E. Rosenbaum
Publisher: John Wiley & Sons
ISBN: 1119143152
Category : Medical
Languages : en
Pages : 589

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Book Description
Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)