Environmental Effects of Dredging, Initial Comparisons of Six Assays for the Assessment of Sediment Genotoxicity PDF Download
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Languages : en
Pages : 11
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This technical note reports and compares initial results of six genotoxicity bioassays applied to dredged sediments and describes progress toward development of a testing protocol to aid in regulatory decisionmaking when genotoxic chemicals are an issue of concern. The Long-term Effects of Dredging Operations Program work unit Genotoxicity of contaminated Dredged Material was initiated in fiscal year 1990 to develop methods for assessing the genotoxic potential of dredged sediments. The impetus driving this new research and development effort was specific regulatory language in section 103 of the Ocean Dumping Act (Marine Protection, Research, and Sanctuaries Act (MPRsA) of 1972) prohibiting the open-water discharge of mutagenic, carcinogenic, or teratogenic substances in other than trace amounts, and language less specific but of similar intent in section 404 of the Clean Water Act (CWA). pg1. JMD.
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Languages : en
Pages : 11
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This technical note reports and compares initial results of six genotoxicity bioassays applied to dredged sediments and describes progress toward development of a testing protocol to aid in regulatory decisionmaking when genotoxic chemicals are an issue of concern. The Long-term Effects of Dredging Operations Program work unit Genotoxicity of contaminated Dredged Material was initiated in fiscal year 1990 to develop methods for assessing the genotoxic potential of dredged sediments. The impetus driving this new research and development effort was specific regulatory language in section 103 of the Ocean Dumping Act (Marine Protection, Research, and Sanctuaries Act (MPRsA) of 1972) prohibiting the open-water discharge of mutagenic, carcinogenic, or teratogenic substances in other than trace amounts, and language less specific but of similar intent in section 404 of the Clean Water Act (CWA). pg1. JMD.
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Category :
Languages : en
Pages : 12
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This technical note reports and compares initial results of six genotoxicity bioassays applied to dredged sediments and describes progress toward development of a testing protocol to aid in regulatory decision making when genotoxic chemicals are an issue of concern.
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Languages : en
Pages : 6
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This technical note describes an approach for assessing the genotoxic potential of dredged material. The use of integrated batteries of rapid and mechanistically interpretable in vitro and in vivo assays in a tiered approach is fundamental to applied toxicology. The research described here brings this approach to the testing of sediments. Work completed to date and future work will mesh to form an advanced and cost-effective methodology. The purpose of this methodology is to increase the accuracy of environmental risk assessments and facilitate making decisions concerning open-water disposal of dredged material. A great number of the contaminants typically found in dredged material are toxic to exposed organisms through effects on DNA. Such effects are usually the result of low-level chronic exposures. These effects can result in reproductive failure of organisms, impaired growth and development of offspring, and tumors (often cancerous) in vertebrates. Collectively, such effects are called 'genotoxicity' and result from damage to the genome of a cell. The damage is heritable, that is, passed on to future cell generations upon duplication of the affected cells.
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Category : Science
Languages : en
Pages : 784
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Languages : en
Pages : 10
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This Technical Note summarizes the proceedings of a workshop that was held March 6-8,1990, at the Environmental Laboratory, US Army Engineer Waterways Experiment Station. The purpose of the workshop was to gain guidance from recognized authorities for the development of sediment bioassays of genotoxicity, that is, mutagenicity, carcinogenicity, immunotoxicity, teratogenicity, and histopathologic potential. The conclusions of the workshop are being used to identify existing genotoxicity bioassays that show promise for application in evaluating sediments, to recommend modifications for testing sediments, and to help direct subsequent research and development of bioassays of genotoxicity by the US Army Corps of Engineers.
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Languages : en
Pages :
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Category :
Languages : en
Pages : 8
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This technical note is the second in a series of three that outline and describe the principal methods that have been developed to test the potential of environmental contaminants for causing mutagenic, carcinogenic, and teratogenic effects. The first in this series (EEDP-04-24) describes methods used to discern genotoxic effects at the subcellular level, while this technical note describes methods used to discern genotoxic effects at the cellular and organ/ organism level. Recent literature citations for each topic are listed in the third technical note (EEDP-04-26) to assist readers in locating source information. A glossary of terms is also provided in Technical Note EEDP-O4-26. The information in these technical notes is intended to provide Corps of Engineers personnel with a working knowledge of the terminology and conceptual basis of genotoxicity testing. To develop an improved understanding of the concepts of genotoxicity, readers are encouraged to review "A Primer in Genotoxicity" (Farvis, Reilly, and Lutz 1993), presented in Volume D-933 of the Environmental Effects of Dredgtng information exchange bulletin.
Author: United States. Environmental Protection Agency. Sediment Oversight Technical Committee
Publisher:
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Category : Environmental protection
Languages : en
Pages : 234
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This document is a compendium of scientifically valid and accepted methods that can be used to assess sediment quality and predict ecological impacts...the intent here is to provide the most useful overall measures or predictors of ecological impacts currently in use rather than procedures that may have limited application outside of a particular regulatory framework... parag The information provided in the compendium on the relative strengths and weaknesses of the different assessment methods can provide assistance in selecting the appropriate methods.
Author: Sven Erik Jorgensen
Publisher: CRC Press
ISBN: 1439829330
Category : Technology & Engineering
Languages : en
Pages : 3513
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Winner of an Outstanding Academic Title Award from CHOICE Magazine Encyclopedia of Environmental Management gives a comprehensive overview of environmental problems, their sources, their assessment, and their solutions. Through in-depth entries and a topical table of contents, readers will quickly find answers to questions about specific pollution and management issues. Edited by the esteemed Sven Erik Jørgensen and an advisory board of renowned specialists, this four-volume set shares insights from more than 500 contributors—all experts in their fields. The encyclopedia provides basic knowledge for an integrated and ecologically sound management system. Nearly 400 alphabetical entries cover everything from air, soil, and water pollution to agriculture, energy, global pollution, toxic substances, and general pollution problems. Using a topical table of contents, readers can also search for entries according to the type of problem and the methodology. This allows readers to see the overall picture at a glance and find answers to the core questions: What is the pollution problem, and what are its sources? What is the "big picture," or what background knowledge do we need? How can we diagnose the problem, both qualitatively and quantitatively, using monitoring and ecological models, indicators, and services? How can we solve the problem with environmental technology, ecotechnology, cleaner technology, and environmental legislation? How do we address the problem as part of an integrated management strategy? This accessible encyclopedia examines the entire spectrum of tools available for environmental management. An indispensable resource, it guides environmental managers to find the best possible solutions to the myriad pollution problems they face. Also Available Online This Taylor & Francis encyclopedia is also available through online subscription, offering a variety of extra benefits for researchers, students, and librarians, including: Citation tracking and alerts Active reference linking Saved searches and marked lists HTML and PDF format options Contact us to inquire about subscription options and print/online combination packages. US: (Tel) 1.888.318.2367 / (email)
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Author:
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ISBN:
Category : Environmental quality
Languages : en
Pages : 588
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