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Author: Samir A. Farghaly
Publisher: Nova Science Publishers
ISBN: 9781634631631
Category : Endometrium
Languages : en
Pages : 0
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Book Description
Endometrial cancer is the most common cancer of the female reproductive system, with more than 49,500 United States women that are diagnosed with the disease each year. It tends to develop after menopause, when a woman is between the ages of 50 and 60. It is the sixth most common cancer in women worldwide (fourteenth most common cancer overall), with 320,000 new cases diagnosed in 2012, and it is the 13th most common cause of death from cancer with nearly 86,000 deaths worldwide. Endometrial cancer occurs when cells of the endometrium undergo a transformation and begin to grow and multiply without the control mechanisms that normally limit their growth. As the cells grow and multiply, they form the cancerous lesion. Cancerous tumors may encroach on and invade neighboring organs or lymph nodes, or they may enter the bloodstream and spread to the bones or distant organs, such as the lungs. This process is called metastasis. Metastatic tumors are the most aggressive and serious of all tumors. Two main types of endometrial cancers exist. Nearly all endometrial cancers are endometrial adenocarcinomas, as they originate from glandular (secreting) tissue. The other type of endometrial cancer, uterine sarcomas, originates in the connective tissue or muscle of the uterus. A subtype of endometrial adenocarcinomas, adenosquamous carcinoma, includes squamous cells (that is, the type of cells found on the surface of the skin and cervix). Other subtypes of endometrial adenocarcinomas are papillary serous adenocarcinomas and clear cell carcinomas. Multidisciplinary teams of experts including specialists in medical oncology, gynecologic oncology, radiology, urology, radiotherapy, and surgery are essential to utilize sophisticated imaging and laboratory tests, to confirm the diagnosis and identify the characteristics of the tumor. They all work together to determine the best treatment approach for the patient. Recent progress in the development of new surgical techniques has transformed the treatment of uterine cancer, resulting in greater surgical precision and fewer complications. In addition, targeted adjuvant therapy has become useful in improving the oncologic outcome of patients with this disease.
Author: Samir A. Farghaly
Publisher: Nova Science Publishers
ISBN: 9781634631631
Category : Endometrium
Languages : en
Pages : 0
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Book Description
Endometrial cancer is the most common cancer of the female reproductive system, with more than 49,500 United States women that are diagnosed with the disease each year. It tends to develop after menopause, when a woman is between the ages of 50 and 60. It is the sixth most common cancer in women worldwide (fourteenth most common cancer overall), with 320,000 new cases diagnosed in 2012, and it is the 13th most common cause of death from cancer with nearly 86,000 deaths worldwide. Endometrial cancer occurs when cells of the endometrium undergo a transformation and begin to grow and multiply without the control mechanisms that normally limit their growth. As the cells grow and multiply, they form the cancerous lesion. Cancerous tumors may encroach on and invade neighboring organs or lymph nodes, or they may enter the bloodstream and spread to the bones or distant organs, such as the lungs. This process is called metastasis. Metastatic tumors are the most aggressive and serious of all tumors. Two main types of endometrial cancers exist. Nearly all endometrial cancers are endometrial adenocarcinomas, as they originate from glandular (secreting) tissue. The other type of endometrial cancer, uterine sarcomas, originates in the connective tissue or muscle of the uterus. A subtype of endometrial adenocarcinomas, adenosquamous carcinoma, includes squamous cells (that is, the type of cells found on the surface of the skin and cervix). Other subtypes of endometrial adenocarcinomas are papillary serous adenocarcinomas and clear cell carcinomas. Multidisciplinary teams of experts including specialists in medical oncology, gynecologic oncology, radiology, urology, radiotherapy, and surgery are essential to utilize sophisticated imaging and laboratory tests, to confirm the diagnosis and identify the characteristics of the tumor. They all work together to determine the best treatment approach for the patient. Recent progress in the development of new surgical techniques has transformed the treatment of uterine cancer, resulting in greater surgical precision and fewer complications. In addition, targeted adjuvant therapy has become useful in improving the oncologic outcome of patients with this disease.
Author: Samir A. Farghaly
Publisher:
ISBN: 9781685079642
Category :
Languages : en
Pages : 0
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Book Description
The purpose of this book is to provide a broad background of several aspects of basic sciences, clinical, therapeutic aspects, and management of endometrial cancer. It provides state-of-the-art information on the molecular genetics, biology, and clinical aspects of premalignant lesions of the endometrium and endometrial cancer. Also, the book chapters provide better understanding of the molecular and cellular events that underlie endometrial cancer. The descriptive and analytical epidemiology of endometrial cancer are presented in Chapter 1. The pathology and molecular diagnosis of endometrial cancer are discussed in Chapter 2. The molecular pathology of endometrial cancer is detailed in Chapter 3. The hereditary aspect of endometrial cancer is highlighted in Chapter 4. Precancerous lesions of the endometrium are reviewed in detail in Chapter 5. Endometrial biomarkers are detailed in Chapter 6. Lymphatic mapping of endometrial cancer is discussed in Chapter 7. Sentinel lymph nodes in endometrial cancer are highlighted in Chapter 8. The current strategies and approaches to treat patients with endometrial cancer are detailed in Chapter 9. Surgical techniques for endometrial cancer are reviewed in Chapter 10. The current treatment of advanced endometrial cancer is discussed in Chapter 11. Adjuvant medical therapeutic modalities are reviewed in Chapter 12. Targeted therapies for advanced endometrial cancer are presented in Chapter 13. The role of ErbB targeted therapy in treating endometrial cancer is discussed in Chapter 14. Finally, the quality of life of women with endometrial cancer is reviewed in Chapter 15. This book is intended for all clinicians and basic medical scientists caring for women with endometrial cancer, including attending surgeons and physicians, clinical fellows, and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology, as well as PhD students and post-doctoral fellows in the basic medical sciences.
Author: Ranu Patni
Publisher: Springer
ISBN: 9811031088
Category : Medical
Languages : en
Pages : 133
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Book Description
This book comprehensively covers endometrial carcinoma, a type of gynecological cancer that is often overlooked but of great interest. Although the incidence of the disease is rapidly increasing, both per se and as part of familial cancer syndromes, there is a great deal of controversy regarding its diagnosis, evaluation and management. This book underlines the significance of endometrial carcinoma, highlights key prevention measures, charts its evaluation, and addresses the stage-by-stage management of this malignancy, with particular attention to the role of minimally invasive surgery. Further, it includes a chapter on future perspectives including robotics, targeted therapies and other developments in the offing. divOverall, the book provides a comprehensive guide to endometrial cancer, which if approached properly, can have an excellent prognosis, thus saving many lives and/or achieving substantially improved quality of life.>
Author: Mansoor R. Mirza
Publisher: Springer
ISBN: 3319645137
Category : Medical
Languages : en
Pages : 324
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Book Description
This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.
Author: Franco Muggia
Publisher: Springer
ISBN: 9783030095864
Category :
Languages : en
Pages : 292
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Book Description
Author: Sumita Mehta
Publisher: Springer Nature
ISBN: 9811553173
Category : Medical
Languages : en
Pages : 306
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Book Description
This book discusses in detail the recent advances in the management of endometrial cancer, including the latest therapies and diagnostic methods. The book focuses on treatment-oriented topics such as the role of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in endometrial cancer, and also explores treatment options in advanced disease stages, including hormonal therapy and targeted therapy. Providing insights into the evidence-based management guidelines for endometrial cancer, this book is a valuable resource for students, trainees and practitioners in the field of gynecology and gyne-oncology.
Author: Noriaki Sakuragi
Publisher:
ISBN: 9781780844404
Category : Endometrium
Languages : en
Pages : 202
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Book Description
This book brings together research related to the diagnosis and management of endometrial cancer
Author:
Publisher:
ISBN: 9783319645148
Category : Electronic books
Languages : en
Pages : 317
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Book Description
This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.
Author: Eric J. Bieber
Publisher: Cambridge University Press
ISBN: 1107040396
Category : Medical
Languages : en
Pages : 1127
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Book Description
Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Author: Shalini Rajaram
Publisher: Springer
ISBN: 8132218922
Category : Medical
Languages : en
Pages : 442
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Book Description
Uterine cancers are the commonest malignancies of the female genital tract in the developed world, and are increasing in numbers world over because of obesity and other life-style changes. Many of these malignancies are hereditary and thus, a better understanding of the genetic and molecular biology is needed. This would lead to appropriate treatment plan for improving the quality of life and long-term survival. This book addresses, in depth, all aspects of uterine malignancies covering both carcinomas and sarcomas. The book is divided into seven sections; the first two sections deal with epidemiology, molecular aspects, familial cancers and pathology and the later sections focus on diagnosis, imaging techniques and comprehensive management of both early stage and advanced cancers. Surgical techniques, adjuvant chemotherapy and radiotherapy have been covered in detail. Apart from the open surgical methods, role of laparoscopy and emerging role of robotic surgery in the contemporary management of endometrial cancers have been discussed. Written by authors with expertise in the field of gynecologic oncology from premier institutes, this book provides up-to-date information on best practice management of uterine malignancies.
