Enantiocontrolled Synthesis of Fluoro-Organic Compounds PDF Download
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Author: V. A. Soloshonok
Publisher: John Wiley & Sons
ISBN:
Category : Science
Languages : en
Pages : 704
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Book Description
Written by a leading expert in the field, this is a comprehensivereview of the methods for preparing stereochemically definedfluorine-containing compounds of biomedical importance. Fluorinated organic compounds are well known for their unusualreactivity but the growing importance of these compounds in thebiomedical field has been accompanied by an increasing awareness ofthe necessity to synthesise and explore the biological propertiesof stereochemically defined fluoro-compounds. This is the firstbook written on this exciting area of research. It contains: * detailed reviews on stereocontrolled synthesis of biologicallyimportant compounds * 21 chapters covering the main areas of asymmetric synthesis andbiocatalysts where fluorine plays a key role * mechanisms and methods for synthesizing fluoro-organiccompounds Written for professionals involved in organic, physical andorganofluorine chemistry, natural product synthesis, biological,pharmaceutical and other life science related industries.
Author: V. A. Soloshonok
Publisher: John Wiley & Sons
ISBN:
Category : Science
Languages : en
Pages : 704
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Book Description
Written by a leading expert in the field, this is a comprehensivereview of the methods for preparing stereochemically definedfluorine-containing compounds of biomedical importance. Fluorinated organic compounds are well known for their unusualreactivity but the growing importance of these compounds in thebiomedical field has been accompanied by an increasing awareness ofthe necessity to synthesise and explore the biological propertiesof stereochemically defined fluoro-compounds. This is the firstbook written on this exciting area of research. It contains: * detailed reviews on stereocontrolled synthesis of biologicallyimportant compounds * 21 chapters covering the main areas of asymmetric synthesis andbiocatalysts where fluorine plays a key role * mechanisms and methods for synthesizing fluoro-organiccompounds Written for professionals involved in organic, physical andorganofluorine chemistry, natural product synthesis, biological,pharmaceutical and other life science related industries.
Author: Tamio Hayashi
Publisher:
ISBN:
Category :
Languages : en
Pages : 14
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Book Description
Author: I.L. Knunyants
Publisher: Springer Science & Business Media
ISBN: 3642702074
Category : Science
Languages : en
Pages : 307
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Book Description
Recently there has been a tremendous growth in the chemistry of fluoroorganic compounds, which find wide applicatiori in various fields of technique and are used to solve some basic theoretical problems. The chemical properties of these compounds are rather specific, as well as the methods for their preparation. We realized that no good handbooks on the preparation offluoro organic compounds were available, whereas the methods of pre paration are scattered in numerous scientific papers and patents. Even such a well-known publication as Organic Syntheses contains just a few methods of preparation of fluoroorganic compounds. As a consequence, not only for newcomers but even for specialists, searching for simple and convenient methods for the preparation of the required compounds is tedious. To alleviate the problem, we undertook to prepare this book, which presents detailed preparation methods of more than 300 flu oro organic compounds. Emphasis has been laid on syntheses of polyfluorinated compounds, since they are of major interest with respect to preparation and utility. Preparation of fluoroorganic compounds is based both on the classical methods of organic chemistry and on the specific ones, which is due to the difficulty or even impossibility of the direct introduction of fluorine into a definite position of organic mole cule. Most organic compounds of fluorine are prepared by a suc cession of conversions of a relatively small number of starting compounds.
Author: B. Baasner
Publisher:
ISBN: 9783131174949
Category :
Languages : en
Pages :
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Book Description
Author: I. L. Knunyants
Publisher:
ISBN:
Category :
Languages : en
Pages : 119
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Book Description
Detailed descriptions of syntheses of fluoro organic compounds are presented. Attention is paid primarily to the methods of synthesizing polyfluorinated compounds, since it is namely these substances that are of greatest interest, both from the procedural and practical point of view. In selecting methods, the authors strove, on the one hand, to offer descriptions for the derivation of such compounds, that can serve as initial products for further syntheses, and, on the other, illustrate as completely as possible the main procedures in fluoro organic chemistry. This report deals with aliphatic fluoro compounds. The description of synthesis for each compound is preceded by an enumeration of its physical characteristics and other methods of its derivation.
Author: Peer Kirsch
Publisher: John Wiley & Sons
ISBN: 3527604197
Category : Science
Languages : en
Pages : 320
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Book Description
In this handbook, Peer Kirsch clearly shows that this exciting field is no longer an exotic area of research. Aimed primarily at synthetic chemists wanting to gain a deeper understanding of the fascinating implications of including the highly unusual element fluorine in organic compounds, the main part of the book presents a wide range of synthetic methodologies and the experimental procedures selected undeniably show that this can be done with standard laboratory equipment. To round off, the author looks at fluorous chemistry and the applications of organofluorine compounds in liquid crystals, polymers and more besides. This long-awaited book represents an indispensable source of high quality information for everyone working in the field.
Author: Tomoya Kitazume
Publisher: Routledge
ISBN: 1351449230
Category : Science
Languages : en
Pages : 278
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Book Description
In the fields of biologically active materials and functional materials, fluorinated organic materials are becoming a focus of significant interest. Over the past decade synthetic methodologies and reagents in fluorine chemistry have been developed, especially stereocontrolled synthetic methods, enzymatic resolution to synthesize enantiomers, fluoromethylated reagents, and fluorination reagents. These methods have contributed to the opening of new pathways for fluorinated materials. However, few fluorinated materials have been put to commercial use. Furthermore, there remain problems to be solved, such as the handling of the materials, availability of reagents and selectivity (stereo-, regio-, and/or chemoselectivity). Research chemists, technical engineers, and graduate students in all branches of chemistry, pharmaceutics, and material science interested in fluorinated materials need to know detailed experimental procedures of how to synthesize the target fluorinated materials. This volume summarizes the chemical and microbial methods for obtaining functionalized fluorinated materials for use as building blocks; detailed experimental methods (reaction conditions, solvent, temperature, handling techniques, etc.); and the stereoview (possible absolute configuration) of the structures with spectral data. Mono-, di-, tri-, and polyfluorinated materials derived from fluorinating agents, fluoromethylated reagents and building blocks are summarized. A chemical name index, molecular formula index, and reagent index are also included. The publication of this monograph will provide access to the enormous possibilities in fluorine chemistry, biological material chemistry, and functionalized material chemistry.
Author: Laszlo Kurti
Publisher: Elsevier
ISBN: 0080575412
Category : Science
Languages : en
Pages : 808
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Book Description
Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings
Author: Jonathan M. Percy
Publisher: Thieme Medical Publishers
ISBN:
Category : Chemistry, Organic
Languages : en
Pages : 456
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Book Description
New edition of the acclaimed reference series, Houben-Weyl. This new ed. is published in English and is available in both print and electronic formats. Clear and systematic, Science of Synthesis provides practical solutions and offers a route through the mass of information available in the primary literature. This one-stop reference tool is: Comprehensive: contains synthetic models selected by world-renowned experts, with full experimental procedures and background information. Reliable: the international editorial board is made up of distinguished chemists with unparalleled experience and competence. Logical and easy-to-navigate: information is organized in a hierarchical system based on the compound or functional group to be synthesized. Authoritative: critically evaluates the preparative applicability and significance of the synthetic methods. Wide-ranging: considers methods from journals, books, and patent literature from the early 1800s up to the present day and presents important synthetic methods for all classes of compounds.
Author: V Prakash Reddy
Publisher: Newnes
ISBN: 044453749X
Category : Science
Languages : en
Pages : 331
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Book Description
Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. - Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds - Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways - Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry
