Emergence and Evolution of Placentation in Mammals PDF Download
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Author: Alysha Shirley Taylor
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Alysha Shirley Taylor
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Robert Pijnenborg
Publisher: Cambridge University Press
ISBN: 1139488686
Category : Medical
Languages : en
Pages : 325
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Book Description
It is now recognized that defective placentation in the human is a cause of many pregnancy complications, such as spontaneous abortion, preterm labor and delivery, pre-eclampsia, intrauterine growth restriction, fetal death and abruptio placenta. These clinical disorders can often have long-term consequences into adulthood, causing cardiovascular disease, obesity and diabetes for the newborn as well as an increased risk of premature death in the mother. This is the first book to be entirely focused on the placental bed, bringing together the results of basic and clinical research in cell biology, immunology, endocrinology, pathology, genetics and imaging to consolidate in a single, informative source for investigators and clinicians. Its core aim is to explore new approaches and improve current clinical practice. This is essential reading for clinicians in obstetric, cardiovascular and reproductive medicine.
Author: C. Redman
Publisher: Wiley-Blackwell
ISBN: 9780632027217
Category : Medical
Languages : en
Pages : 608
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Book Description
The placenta is fascinating and complex. Basically foreign to the maternal body, it can be thought of as an organ transplanted onto the mother's host tissue. As such it embodies all the principles of tissue acceptance and rejection. Many of the risks of pregnancy and labor have now been eliminated and the placenta is likely to be at the root of many of the dangers to the unborn child that remain. A breakdown of the relationship between the placenta and the maternal tissue may turn out to be the cause of the majority of early lost pregnancies.
Author: Koryu Kin
Publisher:
ISBN:
Category :
Languages : en
Pages : 356
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Author: Peter Wooding
Publisher: Springer Science & Business Media
ISBN: 3540787976
Category : Medical
Languages : en
Pages : 304
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Book Description
Science produces fascinating puzzles: why is there such a range of placental structures when other mammalian organs are so structurally uniform ? Why and how did the different placental structures evolve ? Comparative placental studies can facilitate the identification of the common factors in placental growth, differentiation and function and their relevance to possible evolutionary pathways. Comparative Placentation is the only book presenting up-to-date data illustrating the great variety of structure but uniform function of vertebrate placentas from fish to man. This information is essential for selection of suitable models to investigate particular practical problems of impaired or anomalous growth in human and animal placentation. The unique collection of the best light and electron micrographs from the last thirtyfive years which precisely illustrate the structural range in each taxon, make the book the most authoritative publication in this field and a vital source of information for anyone interested on reproductive physiology, anatomy and medicine.
Author: Thomas A. Walsh
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
The presence of a placenta is an important synapomorphy that defines the mammal clade. From the fossil record we know that the first placental mammal lived approximately 125 million years ago, with the chorioallantoic placenta evolving not long after. In this thesis a set of 22 complete genomes from Eutherian, non-Eutherian and outgroup species are compared, the aim being to identify protein-coding and regulatory alterations that are likely to be implicated in the emergence of mammal placenta in the fossil record. To this end we have examined the roles played by positive selection and miRNA regulation in the evolution of the placenta. We have identified those genes that underwent functional shift uniquely in the ancestral placental mammal lineage and that are also heavily implicated in disorders of the placenta. Carrying out a thorough analysis of non-coding regions of the 22 genomes included in the study we identified a cohort of miRNAs that exist only in placental mammals. Many of the placenta related genes described above have multiple predicted "placenta-specific" miRNA binding sites. Together these results indicate a role for both adaptation in protein-coding regions and emergence of novel noncoding regulators in the origin and evolution of mammal placentation.
Author: Kenneth D. Rose
Publisher: JHU Press
ISBN: 9780801880223
Category : Business & Economics
Languages : en
Pages : 282
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Author: Eugene V. Koonin
Publisher: Springer Science & Business Media
ISBN: 1475737831
Category : Science
Languages : en
Pages : 482
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Book Description
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.
Author: Richard P. Shefferson
Publisher: Cambridge University Press
ISBN: 1108138608
Category : Science
Languages : en
Pages : 445
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Book Description
The existing theories on the evolution of senescence assume that senescence is inevitable in all organisms. However, recent studies have shown that this is not necessarily true. A better understanding of senescence and its underlying mechanisms could have far-reaching consequences for conservation and eco-evolutionary research. This book is the first to offer interdisciplinary perspectives on the evolution of senescence in many species, setting the stage for further developments. It brings together new insights from a wide range of scientific fields and cutting-edge research done on a multitude of different animals (including humans), plants and microbes, giving the reader a complete overview of recent developments and of the controversies currently surrounding the topic. Written by specialists from a variety of disciplines, this book is a valuable source of information for students and researchers interested in ageing and life history traits and populations.
Author: Patrick P. L. Tam
Publisher:
ISBN: 9781936113248
Category : Science
Languages : en
Pages : 0
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Book Description
"A subject collection from Cold Spring Harbor perspectives in biology."
