Electrical Interactions in Molecular Biophysics PDF Download
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Author: Raymond Gabler
Publisher: Elsevier
ISBN: 0323154042
Category : Science
Languages : en
Pages : 365
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Book Description
Electrical Interactions in Molecular Biophysics: An Introduction deals with electrical interactions between biomolecules and therefore encompasses two disciplines, molecular biology and physics. The emphasis is on the electrical nature of biochemical or molecular biological reactions. The principles of electrostatics are used to explain some of the basic units of structure on a molecular level. Comprised of nine chapters, this book opens with an overview of the concepts and structures of biochemistry, with particular reference to different structural biochemical groups and how they are used as building blocks in forming molecules. The following chapters discuss the basics of elementary electrostatics; dielectric constants and dipoles; the dipole moments of biomolecules; van der Waals forces; and Debye-Huckel theory. Water and water structure are also considered from a physical standpoint. The final chapter is devoted to experimental techniques that rely upon the electrical properties of biomolecules and explains what types of information can be obtained from each experimental form. This monograph will be of interest to students and practitioners in biochemistry, molecular biology, biophysics, or microbiology.
Author: Raymond Gabler
Publisher: Elsevier
ISBN: 0323154042
Category : Science
Languages : en
Pages : 365
Get Book Here
Book Description
Electrical Interactions in Molecular Biophysics: An Introduction deals with electrical interactions between biomolecules and therefore encompasses two disciplines, molecular biology and physics. The emphasis is on the electrical nature of biochemical or molecular biological reactions. The principles of electrostatics are used to explain some of the basic units of structure on a molecular level. Comprised of nine chapters, this book opens with an overview of the concepts and structures of biochemistry, with particular reference to different structural biochemical groups and how they are used as building blocks in forming molecules. The following chapters discuss the basics of elementary electrostatics; dielectric constants and dipoles; the dipole moments of biomolecules; van der Waals forces; and Debye-Huckel theory. Water and water structure are also considered from a physical standpoint. The final chapter is devoted to experimental techniques that rely upon the electrical properties of biomolecules and explains what types of information can be obtained from each experimental form. This monograph will be of interest to students and practitioners in biochemistry, molecular biology, biophysics, or microbiology.
Author: Nathan R. Zaccai
Publisher: Cambridge University Press
ISBN: 1108508804
Category : Science
Languages : en
Pages : 710
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Book Description
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.
Author: Meyer B. Jackson
Publisher: Cambridge University Press
ISBN: 9780521624411
Category : Medical
Languages : en
Pages : 536
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Book Description
Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.
Author: Christian Holm
Publisher: Springer Science & Business Media
ISBN: 940100577X
Category : Science
Languages : en
Pages : 529
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Book Description
Soft Condensed Matter commonly deals with materials that are mechanically soft and, more importantly, particularly prone to thermal fluctuation effects. Charged soft matter systems are especially interesting: they can be manufactured artificially as polyelectrolytes to serve as superabsorbers in dypers, as flocculation and retention agents, as thickeners and gelling agents, and as oil-recovery process aids. They are also abundant in living organisms, mostly performing important structural (e.g. membranes) and functional (e.g. DNA) tasks. The book describes the many areas in soft matter and biophysics where electrostatic interactions play an important role. It offers in-depth coverage of recent theoretical approaches, advances in computer simulation, and novel experimental techniques. Readership: Advanced undergraduate level in physics, physical chemistry, and theoretical biochemistry.
Author: Benjamin Bederson
Publisher: Springer Science & Business Media
ISBN: 1461215129
Category : Science
Languages : en
Pages : 855
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Book Description
The 20th century has been the century of unparalleled scientific advances fuelled primarily by discoveries made by physicists. The century also represents the life span of the American Physical Society, not coincidentally, and to celebrate both its own centennial and this remarkable century, the APS has prepared this book highlighting the seminal discoveries of the 20th century, with invited articles by the world's most eminent living physicists, including 12 physics Nobel Prize winners. Some 40 chapters cover a broad range of topics in physics written in an engaging and personal style. While the technical level is high, these are not review articles, but rather perspectives on discoveries written by those scientists most closely associated with the original work, as well as future directions of research.
Author: Maik W. Jornitz
Publisher: CRC Press
ISBN: 1351675699
Category : Business & Economics
Languages : en
Pages : 673
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Book Description
Since sterile filtration and purification steps are becoming more prevalent and critical within medicinal drug manufacturing, the third edition of Filtration and Purification in the Biopharmaceutical Industry greatly expands its focus with extensive new material on the critical role of purification and advances in filtration science and technology. It provides state-of-the-science information on all aspects of bioprocessing including the current methods, processes, technologies and equipment. It also covers industry standards and regulatory requirements for the pharmaceutical and biopharmaceutical industries. The book is an essential, comprehensive source for all involved in filtration and purification practices, training and compliance. It describes such technologies as viral retentive filters, membrane chromatography, downstream processing, cell harvesting, and sterile filtration. Features: Addresses recent biotechnology-related processes and advanced technologies such as viral retentive filters, membrane chromatography, downstream processing, cell harvesting, and sterile filtration of medium, buffer and end product Presents detailed updates on the latest FDA and EMA regulatory requirements involving filtration and purification practices, as well as discussions on best practises in filter integrity testing Describes current industry quality standards and validation requirements and provides guidance for compliance, not just from an end-user perspective, but also supplier requirement It discusses the advantages of single-use process technologies and the qualification needs Sterilizing grade filtration qualification and process validation is presented in detail to gain the understanding of the regulatory needs The book has been compilated by highly experienced contributors in the field of pharmaceutical and biopharmaceutical processing. Each specific topic has been thoroughly examined by a subject matter expert.
Author: Maik J. Jornitz
Publisher: CRC Press
ISBN: 0849379547
Category : Medical
Languages : en
Pages : 816
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Book Description
Filtration and Purification in the Biopharmaceutical Industry, First Edition greatly expands its focus with extensive new material on the critical role of purification and the significant advances in filtration science and technology. This new edition provides state-of-the-science information on all aspects of filtration and purification, in
Author: Evgeni Starikov
Publisher: Elsevier
ISBN: 0080461018
Category : Science
Languages : en
Pages : 605
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Book Description
Modern Methods for Theoretical Physical Chemistry of Biopolymers provides an interesting selection of contributions from an international team of researchers in theoretical chemistry. This book is extremely useful for tackling the complicated scientific problems connected with biopolymers' physics and chemistry. The applications of both the classical molecular-mechanical and molecular-dynamical methods and the quantum chemical methods needed for bridging the gap to structural and dynamical properties dependent on electron dynamics are explained. Also included are ways to deal with complex problems when all three approaches need to be considered at the same time. The book gives a rich spectrum of applications: from theoretical considerations of how ATP is produced and used as 'energy currency' in the living cell, to the effects of subtle solvent influence on properties of biopolymers and how structural changes in DNA during single-molecule manipulation may be interpreted.· Presents modern successes and trends in theoretical physical chemistry/chemical physics of biopolymers· Topics covered are of relevant importance to rapidly developing areas in science such as nanotechnology and molecular medicine· Quality selection of contributions from renowned scientists in the field
Author: Maik W. Jornitz
Publisher: Springer
ISBN: 3540330186
Category : Science
Languages : en
Pages : 211
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Book Description
Author: Orjan G. Martinsen
Publisher: Elsevier
ISBN: 0128191082
Category : Technology & Engineering
Languages : en
Pages : 634
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Book Description
Bioimpedance and Bioelectricity Basics, Fourth Edition discusses, in detail, dielectric and electrochemical aspects, as well as electrical engineering concepts of network theory. The book takes readers from an introductory (postgraduate) level to a developed understanding of core dielectric and electrochemical aspects of bioelectricity combined with the necessary electrical engineering concepts, such as network theory, to allow readers to work effectively across the interface of biology, physics and engineering. The book has a highly effective organization, and covers important concepts relating to bioelectricity and impedance, including finite element analysis, endogenic sources, control theory, tissue electrical properties, and invasive measurements. With its concentration on instrumentation and system design, data and analysis, the book is suited to readers with an applied focus on experimentation and device development. It paves an easier and more efficient way for readers seeking basic knowledge about this discipline. This book's focus is on systems with galvanic contact with tissue, and the importance of the geometry of the measuring system cannot be overemphasized. - Contains new pedagogical features that support learning and make this an ideal text for teaching - Includes more content on electrochemistry, cyclic voltammetry, amperometry, cell properties and machine learning - Covers tissue immittance building up from the basics in an accurate and easy to understand manner, supported with figures and examples, with Geometry and instrumentation also covered
