Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis

Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis PDF Author: Claude L. Malmendier
Publisher: Springer Science & Business Media
ISBN: 1461307333
Category : Science
Languages : en
Pages : 345

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Book Description
Plasma lipoproteins constitute a unique macromolecular system of lipid-protein complexes responsible for the transport of lipids from their sites of origin to their sites of utilization either as metabolic fuel or as structural components of cell membranes. Although studies on the role of lipoproteins in the mechanism of lipid transport are meritorious in their own right, the ever-increasing interest in chemical and functional properties of this remarkable class of conjugated proteins stems from the impressive evidence of their direct involvement in the genesis and develop ment of atherosclerotic lesions. The initial emphasis on neutral lipids and phospholipids as the most characteristic constituents of operationally defined lipoprotein classes has shifted in recent years to their protein moieties or apolipoproteins. The discovery of a number of apolipoproteins and characterization of familial hypolipoproteinemias as apolipoprotein deficiency disorders indicated that apolipoproteins play an essential role in maintaining the structural stability and integrity of lipoprotein particles. In addition to their role in the formation of lipoproteins, apolipoproteins were shown to perform a variety of functions in metabolic conversion of lipoproteins and their interactions with cellular surfaces. Results from several laboratories have demonstrated that the chemical and metabolic heterogeneity of operationally-defined lipoprotein classes is due to the presence of several discrete lipoprotein particles with similar physical properties but different and characteristic apolipoprotein composition. Thus, the apolipoproteins have emerged not only as essential structural and functional constituents of lipoproteins but also as unique chemical markers for identifying and classifying lipoprotein particles.

Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis

Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis PDF Author: Claude L. Malmendier
Publisher: Springer Science & Business Media
ISBN: 1461307333
Category : Science
Languages : en
Pages : 345

Get Book Here

Book Description
Plasma lipoproteins constitute a unique macromolecular system of lipid-protein complexes responsible for the transport of lipids from their sites of origin to their sites of utilization either as metabolic fuel or as structural components of cell membranes. Although studies on the role of lipoproteins in the mechanism of lipid transport are meritorious in their own right, the ever-increasing interest in chemical and functional properties of this remarkable class of conjugated proteins stems from the impressive evidence of their direct involvement in the genesis and develop ment of atherosclerotic lesions. The initial emphasis on neutral lipids and phospholipids as the most characteristic constituents of operationally defined lipoprotein classes has shifted in recent years to their protein moieties or apolipoproteins. The discovery of a number of apolipoproteins and characterization of familial hypolipoproteinemias as apolipoprotein deficiency disorders indicated that apolipoproteins play an essential role in maintaining the structural stability and integrity of lipoprotein particles. In addition to their role in the formation of lipoproteins, apolipoproteins were shown to perform a variety of functions in metabolic conversion of lipoproteins and their interactions with cellular surfaces. Results from several laboratories have demonstrated that the chemical and metabolic heterogeneity of operationally-defined lipoprotein classes is due to the presence of several discrete lipoprotein particles with similar physical properties but different and characteristic apolipoprotein composition. Thus, the apolipoproteins have emerged not only as essential structural and functional constituents of lipoproteins but also as unique chemical markers for identifying and classifying lipoprotein particles.

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes PDF Author: Neale Ridgway
Publisher: Elsevier
ISBN: 0444634495
Category : Science
Languages : en
Pages : 625

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Book Description
Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences. - Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry - References from current literature will be included in each chapter to facilitate more in-depth study - Key concepts are supported by figures and models to improve reader understanding - Chapters provide historical perspective and current analysis of each topic

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes PDF Author: J.E. Vance
Publisher: Elsevier
ISBN: 008086080X
Category : Science
Languages : en
Pages : 619

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Book Description
The second edition of this book on lipids, lipoprotein and membrane biochemistry has two major objectives - to provide anadvanced textbook for students in these areas of biochemistry,and to summarise the field for scientists pursuing research inthese and related fields. Since the first edition of this book was published in 1985 theemphasis on research in the area of lipid and membrane biochemistry has evolved in new directions. Consequently, thesecond edition has been modified to include four chapters on lipoproteins. Moreover, the other chapters have been extensivelyupdated and revised so that additional material covering the areas of cell signalling by lipids, the assembly of lipids andproteins into membranes, and the increasing use of molecular biological techniques for research in the areas of lipid, lipoprotein and membrane biochemistry have been included. Each chapter of the textbook is written by an expert in the field, but the chapters are not simply reviews of current literature. Rather, they are written as current, readable summaries of these areas of research which should be readily understandable to students and researchers who have a basic knowledge of general biochemistry. The authors were selected fortheir abilities both as researchers and as communicators. In addition, the editors have carefully coordinated the chapters sothat there is little overlap, yet extensive cross-referencing among chapters.

Lipids and Cardiovascular Disease

Lipids and Cardiovascular Disease PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 226

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Book Description


Triglyceride, High Density Lipoprotein, and Coronary Heart Disease

Triglyceride, High Density Lipoprotein, and Coronary Heart Disease PDF Author: Naomi Miller
Publisher:
ISBN:
Category : Coronary heart disease
Languages : en
Pages : 96

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Book Description
This bibliography is organized into sections on background; relationship of high density lipoprotein, triglyceride, and coronary heart disease; genetics and genetic syndromes; secondary causes of high triglyceride and low high density lipoprotein; measurement of high density lipoprotein and triglyceride; evidence from clinical trials; approach to high triglyceride and low high density lipoprotein; and monographs.

Current Bibliographies in Medicine

Current Bibliographies in Medicine PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 528

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Book Description


Diet and Health

Diet and Health PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309039940
Category : Medical
Languages : en
Pages : 765

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Book Description
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Preventive Cardiology: A Practical Approach, Second Edition

Preventive Cardiology: A Practical Approach, Second Edition PDF Author: Nathan D. Wong
Publisher: McGraw Hill Professional
ISBN: 9780071409964
Category : Medical
Languages : en
Pages : 658

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Book Description
PREVENTIVE CARDIOLOGY is the premier source of clinically relevant information on the prevention of coronary heart disease. Thoroughly updated by international experts, the book discusses screening, risk factors, prevention in special populations, and primary and secondary prevention in the context of the daily practice of medicine. PREVENTIVE CARDIOLOGY is a "must have" for cardiologists and primary care physicians. Review of the first edition: "Excellent...Structured in a way that invites the reader to use it as a comprehensive reference...The combination of theory and guidelines with a practical approach to the patient at risk for cardiovascular diseases is a strength." The New England Journal of Medicine

Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1422

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Book Description


National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1178

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Book Description