Effects of Hormones and Chemical Carcinogens on Rat Mammary Cells in Vitro PDF Download
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Author: James Edward Richards
Publisher:
ISBN:
Category :
Languages : en
Pages : 394
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Author: James Edward Richards
Publisher:
ISBN:
Category :
Languages : en
Pages : 394
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Author: Gloria M. Calaf De Iturri
Publisher:
ISBN:
Category : Growth
Languages : en
Pages : 412
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Author: Alecsandru Ioan Baba
Publisher:
ISBN: 9789732714577
Category : Electronic books
Languages : en
Pages : 787
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Author: Michael Nathan Gould
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 312
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Author: J. M. Peters
Publisher:
ISBN: 9788774941927
Category : Breast
Languages : en
Pages : 190
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Author: Elizabeth K. Weisburger
Publisher: Springer Science & Business Media
ISBN: 9400925263
Category : Medical
Languages : en
Pages : 210
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Book Description
but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Author: Shigeki Miyamoto
Publisher:
ISBN:
Category :
Languages : en
Pages : 276
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Author: Trevor M. Penning
Publisher: Springer Science & Business Media
ISBN: 1617379956
Category : Medical
Languages : en
Pages : 447
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Book Description
This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264122648
Category :
Languages : en
Pages : 27
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This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ...
Author: William Grover Dilley
Publisher:
ISBN:
Category :
Languages : en
Pages : 214
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