Effects of Aerobic Exercise Training on Arterial Stiffness and Autonomic Function in Obese Adults At-risk of Cardiovascular Disease and Type 2 Diabetes PDF Download
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Author: Joshua McGee
Publisher:
ISBN:
Category :
Languages : en
Pages : 128
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Book Description
Obesity is a major risk factor for cardiovascular disease (CVD), CVD mortality, and type 2 diabetes. Arterial stiffness and autonomic dysfunction are independent predictors of CVD and type 2 diabetes. Moreover, African Americans (AA) have a disproportionate prevalence of elevated arterial stiffness compared to Caucasians. Obese individuals have a greater prevalence of diminished autonomic nervous system activity compared to lean individuals. Despite evidence of aerobic exercise training benefiting arterial stiffness and autonomic dysfunction in the general population, optimal intensity and volume for AAs and obese individuals remain unclear. The purpose of this dissertation was to determine whether high-intensity aerobic exercise training improved arterial stiffness and aortic compliance to a greater degree than moderate intensity in obese AAs (study 1), if clinically significant weight loss from a combined hypocaloric diet and aerobic exercise intervention increases heart rate variability (HRV) in obese adults and to evaluate the impact of aerobic exercise volume on HRV during weight maintenance (study 2). Arterial stiffness or aortic compliance did not improve in response to 24 weeks of moderate- or high-intensity, supervised aerobic exercise training at a volume consistent with public health guidelines. However, both groups significantly increased cardiorespiratory fitness compared to the control group. In addition, we observed an inverse relationship between changes in cardiorespiratory fitness and aortic compliance. The results from this study suggest AAs may require greater volumes of weekly aerobic exercise than recommended for the general population to improve arterial stiffness. The 10-week, combined intervention improved major HRV indices of parasympathetic activity. The changes in parasympathetic activity were inversely associated with fasting insulin concentrations. Both groups retained all HRV benefits over the 18-week maintenance phase. The results from this study suggest weight loss via energy restriction and exercise alter autonomic function, leading to improved sympathovagal balance in obese adults, also exercise volumes consistent with physical activity guidelines maintains improvements in autonomic function from weight loss. Collectively, the results of this dissertation provide valuable public health insight for health professionals prescribing aerobic exercise to improve predictors of CVD and type 2 diabetes, specifically arterial stiffness, aortic compliance, and autonomic dysfunction in at-risk, obese adults.
Author: Joshua McGee
Publisher:
ISBN:
Category :
Languages : en
Pages : 128
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Book Description
Obesity is a major risk factor for cardiovascular disease (CVD), CVD mortality, and type 2 diabetes. Arterial stiffness and autonomic dysfunction are independent predictors of CVD and type 2 diabetes. Moreover, African Americans (AA) have a disproportionate prevalence of elevated arterial stiffness compared to Caucasians. Obese individuals have a greater prevalence of diminished autonomic nervous system activity compared to lean individuals. Despite evidence of aerobic exercise training benefiting arterial stiffness and autonomic dysfunction in the general population, optimal intensity and volume for AAs and obese individuals remain unclear. The purpose of this dissertation was to determine whether high-intensity aerobic exercise training improved arterial stiffness and aortic compliance to a greater degree than moderate intensity in obese AAs (study 1), if clinically significant weight loss from a combined hypocaloric diet and aerobic exercise intervention increases heart rate variability (HRV) in obese adults and to evaluate the impact of aerobic exercise volume on HRV during weight maintenance (study 2). Arterial stiffness or aortic compliance did not improve in response to 24 weeks of moderate- or high-intensity, supervised aerobic exercise training at a volume consistent with public health guidelines. However, both groups significantly increased cardiorespiratory fitness compared to the control group. In addition, we observed an inverse relationship between changes in cardiorespiratory fitness and aortic compliance. The results from this study suggest AAs may require greater volumes of weekly aerobic exercise than recommended for the general population to improve arterial stiffness. The 10-week, combined intervention improved major HRV indices of parasympathetic activity. The changes in parasympathetic activity were inversely associated with fasting insulin concentrations. Both groups retained all HRV benefits over the 18-week maintenance phase. The results from this study suggest weight loss via energy restriction and exercise alter autonomic function, leading to improved sympathovagal balance in obese adults, also exercise volumes consistent with physical activity guidelines maintains improvements in autonomic function from weight loss. Collectively, the results of this dissertation provide valuable public health insight for health professionals prescribing aerobic exercise to improve predictors of CVD and type 2 diabetes, specifically arterial stiffness, aortic compliance, and autonomic dysfunction in at-risk, obese adults.
Author: Linda S. Pescatello
Publisher: Springer
ISBN: 3319170767
Category : Medical
Languages : en
Pages : 347
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Book Description
As the first primer on the effects of exercise on human hypertension, Effects of Exercise on Hypertension: From Cells to Physiological Systems provides the state-of-the-art effects of exercise on the many possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on the effects of exercise on physiological systems known to be involved in hypertension development and maintenance as well as less well known aspects of hypertension such as 24-hour ambulatory blood pressure profile and oxidative stress. An emerging area, the effects of resistance exercise training on blood pressure is also covered. A unique aspect of the book is that it covers the effects of exercise mimetics on vascular cell adaptations in order to begin to elucidate some of the cellular mechanisms that may underlie blood pressure reductions with exercise training. Lastly, the book will end with a chapter on the interactive effects of genes and exercise on blood pressure. Chapters are grouped by physiological system or mechanism. The text begins with two overview chapters; one on the general effects of aerobic exercise training and the second on the general effects of resistance exercise training on blood pressure. Each chapter begins with a bulleted list of key points. Effects of Exercise on Hypertension: From Cells to Physiological Systems will be of great value to professional individuals in cardiovascular medicine, the cardiovascular sciences, allied health care professionals, and medical and graduate students in the cardiovascular sciences and medicine.
Author: Anka Brozic
Publisher:
ISBN: 9780494389188
Category :
Languages : en
Pages : 206
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Book Description
In patients with type 2 diabetes (DM2) arterial stiffness, heart rate variability (HRV), high sensitivity C-reactive protein (hs-CRP) and hyperaemic calf blood flow were measured before and after 12 weeks of combined aerobic and resistance exercise training. Arterial stiffness and HRV were also measured after 20 minutes of moderate, aerobic exercise pre and post exercise training. A single acute bout of aerobic exercise results in significantly elevated central arterial stiffness both before and after 12 weeks of training whereas AAI is reduced prior to training only. After 12 weeks of training, significant improvements were found in: C-F PWV (p=0.026); augmentation index (p= 0.005); peak oxygen uptake (p=.002) fasting plasma glucose (p=0.041), abdominal circumference (p=0.001), BMI (p=0.004) and body fat (p=0.032). Improvements in arterial stiffness were not associated with any change in anthropometric measurements, aerobic fitness, hs-CRP or indices of heart rate variability.
Author: Hasan Sozen
Publisher: BoD – Books on Demand
ISBN: 9535127446
Category : Science
Languages : en
Pages : 158
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Book Description
Although fitness and health have similar properties, they are, in reality, two very different concepts. While health refers to the absence of diseases, fitness refers to the degree of body functioning and the ability of the body to handle physical demands. The more efficient the body functions, the higher the level of fitness. The higher the level of fitness, the greater the chance of the body being free of diseases and maintaining a healthy state.
Author: Aaron Scott Kelly
Publisher:
ISBN:
Category :
Languages : en
Pages : 162
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Book Description
Author: Peter Kokkinos
Publisher: Jones & Bartlett Learning
ISBN: 0763756121
Category : Health & Fitness
Languages : en
Pages : 434
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Book Description
Health Sciences & Professions
Author: Dr. I. Devi Vara Prasad
Publisher: Lulu.com
ISBN: 1387529390
Category : Science
Languages : en
Pages : 180
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Book Description
Health is the general condition of a person in all aspects. It is also a level of functional and/or metabolic efficiency of an organism, often implicitly human. At the time of the creation of the World Health Organization (WHO), in 1948, health was defined as being "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity". In 1986, the WHO, in the Ottawa Charter for Health Promotion, said that health is "a resource for everyday life, not the objective of living. Health is a positive concept emphasizing social and personal resources, as well as physical capacities." Overall health is achieved through a combination of physical, mental, emotional, and social well-being, which, together is commonly referred to as the Health Triangle.Good health means that all organs of the body are working efficiently. The important proverb is, 'Health is wealth', 'if health is lost everything is lost', and is realized more in its absence than by its presence.
Author: Laurel A. Ayvazian
Publisher:
ISBN:
Category : Arteries
Languages : en
Pages : 90
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Book Description
ABSTRACT: Type 2 diabetes mellitus (T2DM) increases cardiovascular disease (CVD) risk. Increased arterial stiffness is an additional, independent risk factor and may be important to identify in those who are already at increased risk. Exercise is an important component of diabetes self-management and has the potential to influence arterial stiffness. Aerobic exercise has consistently been associated with lower levels of arterial stiffness. While resistance exercise is important in regulating glycemic control and preventing sarcopenia in aging adults, some research indicates resistance exercise may increase stiffness. Women between the ages of 50 and 75 were recruited to participate in a healthy control (CON n= 10) or T2DM (n = 6) group. Subjects completed a full body, moderateintensity (60-85% 1 RM) resistance exercise protocol. Carotid-femoral pulse wave velocity (PWV), radial pulse wave analysis (PWA), blood pressure (BP), heart rate (HR), and serum nitric oxide (NO) and endothelin-1 (ET-1) were measured pre- and postexercise, as well as after one hour of recovery. Additional PWA, BP, and HR measurements were taken 30 min postexercise. A significant (p
Author: Kazuyuki Kanosue
Publisher: Springer
ISBN: 4431553339
Category : Medical
Languages : en
Pages : 333
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Book Description
The aim of this book is to present current views about physical activity and the benefits of physical activity in preventing and ameliorating various health conditions that are of worldwide concern. This book was developed as a compilation of the accomplishments of the five-year Global COE (Center of Excellence) “Sport Sciences for the Promotion of Active Life” Program at the Faculty of Sport Sciences of Waseda University, Saitama, Japan. The first part establishes the research methodology and discusses the current status of physical activity. Topics covered include the prevalence of physical inactivity and highly sedentary behavior in different populations as well as strategies that can be adopted to promote physical activity. The second part focuses on the physiological effects of physical activity. Topics covered include physiological responses to exercise by the autonomic nervous system, the endocrine system, vascular functioning, postprandial blood glucose control, and inflammatory processes. The relationship between exercise and appetite is discussed, as is the influence of exercise on food intake and weight regulation. Additionally, the influence of exercise on protein regulation and posttranslational modifications is introduced. The final part discusses the role of physical activity in preventing lifestyle-related health issues and improving the quality of life, especially for the elderly. The contents should be of interest to anyone who is concerned with the human physiologic response to exercise and the promotion of healthy lifestyles, including sports and exercise science researchers as well as those involved with medicine, public health, physiology, nutrition, and elder care.
Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330
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Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
