The Ebola Epidemic in West Africa

The Ebola Epidemic in West Africa PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450063
Category : Medical
Languages : en
Pages : 137

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Book Description
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.

The Ebola Epidemic in West Africa

The Ebola Epidemic in West Africa PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450063
Category : Medical
Languages : en
Pages : 137

Get Book

Book Description
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.

Ebola and Marburg Viruses

Ebola and Marburg Viruses PDF Author: Hans-Dieter Klenk
Publisher: Garland Science
ISBN: 9780954523237
Category : Cell physiology
Languages : en
Pages : 392

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Book Description
The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Ebola Prevention and Control

Ebola Prevention and Control PDF Author: Angela Dramowski
Publisher: Bettercare
ISBN: 9781920218867
Category :
Languages : en
Pages : 166

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Book Description
Ebola Prevention and Control is a crucial guide to managing, preventing and controlling Ebola and other viral haemorrhagic fevers, especially in resource-limited settings. Chapters cover: - Virology and epidemiology - Patient management - Protection of healthcare workers - Support services and documentation - Communication and community engagement Ebola Prevention and Control is suited to healthcare workers, managers and administrators tasked with preventing, controlling and managing outbreaks of viral haemorrhagic diseases.

Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level

Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level PDF Author: World Health Organization
Publisher:
ISBN: 9789241549929
Category : Medical
Languages : en
Pages : 92

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Book Description
Health care-associated infections (HAI) are one of the most common adverse events in care delivery and a major public health problem with an impact on morbidity, mortality and quality of life. At any one time, up to 7% of patients in developed and 10% in developing countries will acquire at least one HAI. These infections also present a significant economic burden at the societal level. However, a large percentage are preventable through effective infection prevention and control (IPC) measures. These new guidelines on the core components of IPC programmes at the national and facility level will enhance the capacity of Member States to develop and implement effective technical and behaviour modifying interventions. They form a key part of WHO strategies to prevent current and future threats from infectious diseases such as Ebola, strengthen health service resilience, help combat antimicrobial resistance (AMR) and improve the overall quality of health care delivery. They are also intended to support countries in the development of their own national protocols for IPC and AMR action plans and to support health care facilities as they develop or strengthen their own approaches to IPC. These are the first international evidence-based guidelines on the core components of IPC programmes. These new WHO guidelines are applicable for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.

CDC Guidance on Ebola Virus (EVD)

CDC Guidance on Ebola Virus (EVD) PDF Author: Center For Disease Control
Publisher: International Publications Media Group
ISBN: 1632670119
Category : Medical
Languages : en
Pages : 159

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Book Description
This guidance provides guidelines for handling inquiries and responding to patients with suspected Ebola symptoms; explanation of signs and symptoms of Ebola; prevention and diagnosis of the Ebola Virus Disease (EVD).

Ebola Virus Disease (EVD)

Ebola Virus Disease (EVD) PDF Author: Hilaire Verreau
Publisher:
ISBN: 9781536162912
Category : Ebola virus disease
Languages : en
Pages : 118

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Book Description
To mitigate the spread of the rare and deadly disease Ebola, Ebola Virus Disease (EVD): Outbreaks, Control and Prevention Strategies begins with the proposition of a mathematical model with vital dynamics and two preventive measures: quarantine and isolation. Humanitarian issues in Ebola prevention and control are explored, as well as the cultural practices and social norms during outbreaks. Additionally, some innovative approaches in the humanitarian response to prevention and control are discussed. The authors expose the dilemma Ebola poses to within the healthcare system, where healthcare providers are caught between the over-arching quest for self-preservation from a highly virulent disease and the professional demand of prioritising the interests of the patients over self. In conclusion, the authors describe successfully developed drug candidates from their laboratory for the treatment Ebola using EBOV protein structure, such as VP24, VP35, VP40, nucleoprotein, and glycoprotein.

Global Management of Infectious Disease After Ebola

Global Management of Infectious Disease After Ebola PDF Author: Sam F. Halabi
Publisher: Oxford University Press
ISBN: 0190604905
Category : Medical
Languages : en
Pages : 256

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Book Description
The 2014-2015 Ebola outbreak in West Africa shocked the world with its devastation and its rapid migration to multiple continents. As the systems meant to respond to this sort of epidemic failed, the disease exposed not just weaknesses in international infectious disease surveillance and management, but the failures of governments, humanitarian organizations, and international institutions to handle the legal, ethical, and economic questions that arose with an event of this scale. GLOBAL MANAGEMENT OF INFECTIOUS DISEASE AFTER EBOLA unites the insights of Ebola's first responders with those the world's foremost experts in law, economics, vaccine development, and global migration to identify missed opportunities from the Ebola crisis -- and to apply these lessons to emerging infectious disease threats. Framed with critical discussions of both the global health financing infrastructures that precipitated the response and the ethical and human rights dilemmas that resulted from it, this volume is much more than postmortem to an outbreak: it is a vital, sometimes damning examination of where we've been and where we're going in the face of emerging infectious diseases.

Ebola

Ebola PDF Author: Joseph R. Masci
Publisher: CRC Press
ISBN: 1351646168
Category : Medical
Languages : en
Pages : 276

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Book Description
Ebola: Clinical Patterns, Public Health Concerns is a concise description and discussion of the Ebola virus and disease. The intended audience is medical practitioners, including those working in endemic areas as well as health-facility planners and public health practitioners. The book fills an important gap between large texts covering not only Ebola but other hemorrhagic fever viruses and brief pamphlet-style publications on the public health aspects of the infection. In light of the recent large outbreak in West Africa, this book is a part of the developing foundation needed to deal with emerging diseases.

Ebola: Information for Healthcare Workers and Settings - For Your Reference

Ebola: Information for Healthcare Workers and Settings - For Your Reference PDF Author: eRegs & Guides
Publisher: eregs & guides
ISBN:
Category : Medical
Languages : en
Pages : 197

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Book Description
Guidance & Recommendations Infection Prevention and Control for Hospitalized Patients with Known or Suspected Ebola in U.S. Hospitals Guidance on Personal Protective Equipment To Be Used by Healthcare Workers During Management of Patients with Ebola Virus Disease in U.S. Hospitals, Including Procedures for Putting On (Donning) and Removing (Doffing) Environmental Infection Control in Hospitals for Ebola Virus – Interim Guidance Recommendations for Safely Performing Acute Hemodialysis in Patients with Ebola Virus Disease in U.S. Hospitals Safe Handling of Human Remains of Ebola Patients in U. S. Hospitals and Mortuaries Ebola-Associated Waste Management Patient Evaluation Algorithm - Evaluating Returned Travelers for Ebola, US Checklist for Patients Being Evaluated for Ebola in the U.S. Laboratory (specimen collection, transport, testing, submission) Specimen Collection, Transport, Testing, and Submission for Persons Under Investigation for Ebola in the U.S. - Interim Guidance Factsheet - Visual format Packaging and Shipping Clinical Specimens Diagram Frequently Asked Questions for U.S. Clinical Laboratories Compliance with Select Agent Regulations for Laboratories Handling Patient Specimens that are Known or Suspected to Contain Ebola Virus – Interim Guidance

How to Prevent the Spread of Ebola

How to Prevent the Spread of Ebola PDF Author: Yinka Vidal
Publisher: Lara Publications Inc
ISBN: 0964081881
Category : Health & Fitness
Languages : en
Pages : 250

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Book Description
How to Prevent the Spread of EBOLA: Effective Strategies to Reduce Facility Acquired Infections and Reduce Super Bugs Outbreak. This book is divided into ten different sections targeting critical issues of concern about Ebola and the processes of preventing Ebola spread as a nosocomial infection. It starts with allaying people’s fear and discussing facts about the clinical aspects of Ebola virus infection. It discusses different types of Ebola viruses and their pathogenesis; routes of infection; clinical manifestations and progression of the disease; immunopathology and cellular toxicity; progressive tissue damage and multi-organ failures; effective management of the disease; and the discussion of some case studies. This Ebola monograph also discusses some of the lingering questions raised by the public about Ebola and addresses these controversial issues with facts. Some of the questions discussed include, What are the indicators for the survivability of the Ebola virus once a patient is infected? Can Ebola virus be aerosolized? What are the differences between the acute phase of the illness and the subclinical, asymptomatic, or nonclinical Ebola virus infections? Where was the first Ebola infection, in West Africa or in Europe? Can the Ebola virus infection be caught through kissing an infected person? When a blood test is negative for Ebola virus, is a patient free of Ebola virus? Can Ebola virus be transmitted through breast milk, semen or vaginal fluids? Was the virulent Ebola virus able to enter the human population by an accidental release due to a lab accident? Can the outbreak of Reston Ebola virus infections in the Philippines among nonhuman primates be dangerous to human population with the evidence of abortive infection in some farm workers? What is the nature of the current virus epidemic in U.S. farms, killing millions of piglets? Is this epidemic swine virus similar to Ebola and how dangerous is it to the human population? What are the lessons learned from the clinical management of Ebola patients that can be applied to the treatment of other viral infections like the Bourbon virus newly discovered in Kansas? What is the chronicity of Ebola infection and the long term effects, after clinical cure? For answers to these questions and more, read the book, How to Prevent the Spread of Ebola Virus Infection. Many healthcare institutions including hospitals, clinics, physician's offices, dentist's offices will find this book very useful to help prevent the rise of facility-acquired infections. Over 600 pages of leading medical journal articles are reviewed in this book giving scientific explanations for the questions raised by Ebola virus infection. In reviewing these research reports, it is evident, that we have effective treatment for Ebola virus infection as a multi-pronged approach in the process of effective clinical management of the disease.