Dynamic Aspects of the Keratin Intermediate Filament (IF) Network Studied by Microinjection of Biotinylated Type I Keratin Into Living Cells PDF Download
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Author: Rita Karen Miller
Publisher:
ISBN:
Category :
Languages : en
Pages : 422
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Author: Rita Karen Miller
Publisher:
ISBN:
Category :
Languages : en
Pages : 422
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Author: Jens-Friedrich Nolting
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Intermediate filaments are a major component of the eukaryotic cytoskeleton along with microtubules and microfilaments and play a key role in cell mechanics. One representative of this class of proteins, which exemplifies the mechanical importance of intermediate filaments, is keratin. In specific cells, keratin intermediate filaments can form bundles, which are organized in a cell wide network. One function of this network is to provide the cell with the ability to withstand potentially harmful mechanical forces and to ensure the integrity of the cell. In this study, the dynamic motion of ...
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 738
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Author: Karen Lynn Vikstrom
Publisher:
ISBN:
Category :
Languages : en
Pages : 344
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Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 796
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Author: James Murray Luck
Publisher: Annual Reviews
ISBN:
Category : Medical
Languages : en
Pages : 1288
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Author:
Publisher: Academic Press
ISBN: 9780128034705
Category : Science
Languages : en
Pages : 0
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Book Description
Intermediate Filament Proteins, the latest volume in the Methods in Enzymology series covers all the intermediate filaments in vertebrates and invertebrates, providing a unique understanding of the multiple different tissue-specific intermediate filaments. This volume also covers the latest methods that are currently being used to study intermediate filament protein function and dynamics. It will be an important companion for any experimentalist interesting in studying this protein family in their cell or organism model system.
Author: R.D. Goldman
Publisher: Springer
ISBN: 9781475796063
Category : Science
Languages : en
Pages : 480
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Book Description
Research activity on intermediate filaments (IF) has increased dramatically over the past decade. For the most part, this surge of interest is due to their identification as ubiquitous constituents of the cytoskeleton and karyoskeleton (nuclear matrix) of eukaryotic cells and the fact that we know very little regarding their functions. In sharp contrast to the other major cytoskeletal systems, microfilaments and microtubules, IF exhibit a high degree of heterogeneity with regard to their protein subunit composition. Indeed, one can only marvel at the number of different IF polypeptides, their associated proteins (IFAP) and, consequently, the number of genes involved in encoding the multiple constituents of the various IF networks found in different cell types. The chapters in this book demonstrate how various experimental approaches involv ing cellular, molecular, biochemical, and immunological methods have been utilized to generate information regarding the structure and function of IF. To this end, we have gathered together chapters from experts in the major fields of IF research. In each chapter, the authors have combined reviews of the available scientific literature with their own ideas on current and future directions for IF research. The chapters have been divided into five major sections which are concerned with the subcellular organization of IF, the molecular structure of IF, the differential expression of IF genes, descriptions of associ ated proteins involved in the intracellular organization of IF, and finally an analysis of the changes seen in IF in pathological conditions.
Author: David A. D. Parry
Publisher: R G Landes Company
ISBN: 9781570591204
Category : Science
Languages : en
Pages : 183
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Book Description
Covers the structure and role of intermediate filament (IF) proteins in a variety of cell types. The text examines the expression of IF proteins, the hierarchical assembly of those proteins into molecules, oligomers, protofilaments, protofilbrils and intact IF.
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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