Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer PDF Author: Che-Pei Kung
Publisher: Frontiers Media SA
ISBN: 2889630307
Category :
Languages : en
Pages : 130

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Book Description
Metabolic diseases and cancers account for half of all mortalities in the world, underscoring the significance of understanding the etiology of these diseases and developing effective therapies. Genomic research in the 21st century has brought cancer and metabolic disease, two once seemingly parallel ailments, as close to each other as they’ve ever been. Many genetic factors have been found to display functions regulating both cancer and metabolic disease. In this research topic: "Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both MetabolicDisease and Cancer", you will be introduced to individual genes, as well as genetic pathways that play important roles in influencing the progression of both metabolic disease and cancer. By no means covering an exhaustive list of genes qualified, this collection of articles rather serves as a precursor of what is yet to come in biomedical research. It paints the big picture of one of the major fields contributing to the future of “precision medicine”.

Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer PDF Author: Che-Pei Kung
Publisher: Frontiers Media SA
ISBN: 2889630307
Category :
Languages : en
Pages : 130

Get Book Here

Book Description
Metabolic diseases and cancers account for half of all mortalities in the world, underscoring the significance of understanding the etiology of these diseases and developing effective therapies. Genomic research in the 21st century has brought cancer and metabolic disease, two once seemingly parallel ailments, as close to each other as they’ve ever been. Many genetic factors have been found to display functions regulating both cancer and metabolic disease. In this research topic: "Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both MetabolicDisease and Cancer", you will be introduced to individual genes, as well as genetic pathways that play important roles in influencing the progression of both metabolic disease and cancer. By no means covering an exhaustive list of genes qualified, this collection of articles rather serves as a precursor of what is yet to come in biomedical research. It paints the big picture of one of the major fields contributing to the future of “precision medicine”.

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism PDF Author: Anne Le
Publisher: Springer
ISBN: 331977736X
Category : Medical
Languages : en
Pages : 186

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Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Double-edged swords: Important factors connecting metabolic disorders and cancer development - from basic research to translational applications

Double-edged swords: Important factors connecting metabolic disorders and cancer development - from basic research to translational applications PDF Author: Che-Pei Kung
Publisher: Frontiers Media SA
ISBN: 2832519393
Category : Medical
Languages : en
Pages : 139

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Book Description


Inflammation and Cancer

Inflammation and Cancer PDF Author: Bharat B. Aggarwal
Publisher: Springer
ISBN: 3034808372
Category : Medical
Languages : en
Pages : 489

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Book Description
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Cancer Therapy: The Challenge of Handling a Double-Edged Sword

Cancer Therapy: The Challenge of Handling a Double-Edged Sword PDF Author: Raquel Abalo
Publisher: Frontiers Media SA
ISBN: 2889766446
Category : Science
Languages : en
Pages : 345

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Book Description


Nutrition in the Prevention and Treatment of Disease

Nutrition in the Prevention and Treatment of Disease PDF Author: Ann M. Coulston
Publisher: Academic Press
ISBN: 0123918847
Category : Health & Fitness
Languages : en
Pages : 921

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Book Description
This comprehensive clinical nutrition textbook uniquely focuses on the clinical applications and disease prevention of nutrition, clearly linking the contributions of basic science to applied nutrition research and, in turn, to research-based patient care guidelines.

The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment

The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment PDF Author: Hiromi Wada
Publisher: Frontiers Media SA
ISBN: 2832526934
Category : Medical
Languages : en
Pages : 164

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Book Description


Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment

Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment PDF Author: Shuyu Zhang
Publisher: Frontiers Media SA
ISBN: 2832502318
Category : Medical
Languages : en
Pages : 364

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Book Description


Signal Transduction in Cancer

Signal Transduction in Cancer PDF Author: David A. Frank
Publisher: Springer Science & Business Media
ISBN: 1402073402
Category : Medical
Languages : en
Pages : 358

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Book Description
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Modern Nutrition in Health and Disease

Modern Nutrition in Health and Disease PDF Author: A. Catherine Ross
Publisher: Jones & Bartlett Learning
ISBN: 1284220311
Category : Health & Fitness
Languages : en
Pages : 1645

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Book Description
This widely acclaimed book is a complete, authoritative reference on nutrition and its role in contemporary medicine, dietetics, nursing, public health, and public policy. Distinguished international experts provide in-depth information on historical landmarks in nutrition, specific dietary components, nutrition in integrated biologic systems, nutritional assessment through the life cycle, nutrition in various clinical disorders, and public health and policy issues. Modern Nutrition in Health and Disease, Eleventh Edition, offers coverage of nutrition's role in disease prevention, international nutrition issues, public health concerns, the role of obesity in a variety of chronic illnesses, genetics as it applies to nutrition, and areas of major scientific progress relating nutrition to disease.