Reactor Dosimetry in the 21st Century

Reactor Dosimetry in the 21st Century PDF Author: Jan Wagemans
Publisher: World Scientific
ISBN: 9789812705563
Category : Science
Languages : en
Pages : 764

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Book Description
This book presents the state of the art in reactor dosimetry as applied to nuclear power plants and to high performance research reactors, accelerator-driven systems and spallation sources. The reader will also find the latest advances in computer code development for radiation transport and shielding. In addition, the book focuses on radiation measurement techniques.

Reactor Dosimetry in the 21st Century

Reactor Dosimetry in the 21st Century PDF Author: Jan Wagemans
Publisher: World Scientific
ISBN: 9789812705563
Category : Science
Languages : en
Pages : 764

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Book Description
This book presents the state of the art in reactor dosimetry as applied to nuclear power plants and to high performance research reactors, accelerator-driven systems and spallation sources. The reader will also find the latest advances in computer code development for radiation transport and shielding. In addition, the book focuses on radiation measurement techniques.

Reactor Dosimetry State Of The Art 2008 - Proceedings Of The 13th International Symposium

Reactor Dosimetry State Of The Art 2008 - Proceedings Of The 13th International Symposium PDF Author: Wim Voorbraak
Publisher: World Scientific
ISBN: 9814468290
Category : Science
Languages : en
Pages : 761

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Book Description
This book gives the state of the art in the field of reactor dosimetry as applied in nuclear power plants and research reactors. Surveillance programs are presented for nuclear power plants in Europe, including Russia and Ukraine, USA, Argentina and Korea. New cross-section measurements from most of the European, American and Japanese research reactors are reported. The latest developments in computer code development for radiation transport and shielding calculations, and radiation measurement techniques are also highlighted.

Reactor Dosimetry

Reactor Dosimetry PDF Author: John G. Williams
Publisher: ASTM International
ISBN: 0803128843
Category : Nuclear power plants
Languages : en
Pages : 884

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Book Description
Comprising the proceedings of the Tenth International Symposium on Reactor Dosimetry held in Osaka, Japan in September 1999, this volume contains some 100 papers, plus three keynote speeches, arranged in seven sections that cover the technical scope of the symposium. The first two sections consist o

Frontiers in Neutron Capture Therapy

Frontiers in Neutron Capture Therapy PDF Author: M. Frederick Hawthorne
Publisher: Springer
ISBN: 1461512859
Category : Medical
Languages : en
Pages : 1389

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Book Description
Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology. Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.

Reactor Dosimetry

Reactor Dosimetry PDF Author: David W. Vehar
Publisher: ASTM International
ISBN:
Category : Science
Languages : en
Pages : 536

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Book Description
"The latest edition of this popular ASTM series provides an extensive overview of the latest advances in reactor dosimetry. As operating nuclear power reactors have aged and continue to operate on extended operating licenses, new pressure vessel surveillance techniques have been required. Eastern European pressurized water reactors, especially those of the VVER-440 type, continue to have greater concerns about steel embrittlement, because of higher neutron radiation exposures than most Western European and US reactors. Accordingly, broader dosimetry studies are being made on the VVER reactors through retrospective dosimetry, ex-vessel dosimetry, and careful re-analysis of previously reported data."--Publisher's website.

Microdosimetric Response of Physical and Biological Systems to Low- and High-LET Radiations

Microdosimetric Response of Physical and Biological Systems to Low- and High-LET Radiations PDF Author: Yigal Horowitz
Publisher: Elsevier
ISBN: 0080462936
Category : Science
Languages : en
Pages : 501

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Book Description
One of the aims of this book was to focus the attention of specialists to the diversity of the effects of the ionising radiation on biological and physical systems. Special emphasis has been placed on the exquisite complexities/differences introduced by high ionisation density versus low ionisation density irradiation in both biological and physical systems (Scholz – Chapter 1, Horowitz – Chapter 2, Olko – Chapter 3). As well we wanted to point out the need for novel experimental and theoretical approaches required to advance the important fields of micro and nanodosimetry. Important first steps have already been taken, for example, the accelerated application of semiconductor detectors in their various forms to microdosimetry and as well to practical, important applications in the radiation dosimetry of oncological procedures (Rosenfeld – Chapter 6). The vast number of applications of TLD to radiation dosimetry are not neglected; a special chapter is devoted to the application of TLDs to medical dosimetry applications (Mobit and Kron – Chapter 7) as well as a tutorial approach in an additional chapter to the cavity theories required to extrapolate dose from the detector medium to the tissue medium (Mobit and Sandison - Chapter 5). One of the major features of this book is the intensive, in depth, coverage of the theory and modelling of TL both from the solid state physics point of view (Chen – Chapter 4) and the microdosimetic point of view (Horowitz – Chapter 2 and Olko – Chapter 3). The many puzzling, quaint, quizzical features of TL science can now be understood in the framework of these advanced theoretical models, explained in straightforward, understandable terms.· Quantifies/unifies the effects of ionising radiation in both the biological and physical systems· Authoritative treatment of applications of semiconductor detectors and thermoluminescence dosemeters in medica l radiation dosimetry· Basic and advanced aspects of microdosimetry applied to both biological and physical systems· In-depth review of the effects of the density of ionising radiation in tsl and osl · Concise and elegant treatment of cavity theory in medical oncological dosimetry· Comprehensive review of this important interdisciplinary field including hundreds of ilustrations and references

Progress in Neutron Capture Therapy for Cancer

Progress in Neutron Capture Therapy for Cancer PDF Author: B.J. Allen
Publisher: Springer Science & Business Media
ISBN: 1461533848
Category : Medical
Languages : en
Pages : 641

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Book Description
Despite the many advances made in the diagnosis and therapy of cancer, the mortality rate is still about half that of the incidence rate. However, the odds are not evenly distributed. Prognosis for some cancers is good, but for others, few patients will survive 12 months. This latter group of cancers is characterised by a proclivity to disseminate malignant cells in the host organ. The degree of surgery possible may be limited by the critical nature of the organ, and chemotherapy and radiotherapy are of palliative value only. In some cases systemic metastases occur, but in other cases, failure to achieve local control results in death. First among these cancers are the high grade brain tumours, astrocytoma 3,4 and glioblastoma multiforme. Local control of these tumours should lead to cure. Other cancers melanoma metastatic to the brain, for which a useful palliative therapy is not yet available, and pancreatic cancer for which localised control at an early stage could bring about improved prognosis. Patients with these cancers have little grounds for hope. Our primary objective is to reverse this situation with Neutron Capture Therapy (NCT). The purpose of this fourth symposium is to hasten the day whereby patients with these cancers can reasonably hope for substantial remissions. The first symposium on NCT was held in Boston in 1983, followed by Tokyo in 1985 and Bremen, Germany in 1988.

Boron Compounds Suitable for Neutron Capture Therapy for the Treatment of Cancer

Boron Compounds Suitable for Neutron Capture Therapy for the Treatment of Cancer PDF Author:
Publisher:
ISBN:
Category : Boron
Languages : en
Pages : 166

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Book Description
An important aspect of boron neutron capture therapy (BNCT) is the determination of the biological distribution of the boron within an organism at some point in time after administration of a boron-containing species. To that end a variety of techniques have been developed and applied to the analysis of boron. These techniques include prompt gamma analysis, colorimetric techniques, and most recently, Inductively Coupled Plasma Atomic Emission spectroscopy (ICP-AES) techniques. The synthesis of new boron compounds for BNCT and understanding the mechanisms by which existing compounds achieve tumor localization is in. a very active stage of development internationally. Such research programs will undoubtedly contribute to improving the possibility for a new clinical trial of this binary therapeutic system in the United States. The papers presented in these proceedings present research into a wide variety of these techniques.

Neutron Capture Therapy

Neutron Capture Therapy PDF Author: Wolfgang A.G. Sauerwein
Publisher: Springer Science & Business Media
ISBN: 3642313345
Category : Medical
Languages : en
Pages : 545

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Book Description
Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.

Cancer Neutron Capture Therapy

Cancer Neutron Capture Therapy PDF Author: Y. Mishima
Publisher: Springer Science & Business Media
ISBN: 147579567X
Category : Medical
Languages : en
Pages : 893

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Book Description
There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994.