Disturbance of Cardiovascular Structure and Function in Obesity and Metabolic Syndrome PDF Download
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Author: Chiew Ying Wong
Publisher:
ISBN:
Category : Obesity
Languages : en
Pages : 282
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Book Description
Author: Chiew Ying Wong
Publisher:
ISBN:
Category : Obesity
Languages : en
Pages : 282
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Book Description
Author: H. Böhles
Publisher: CRC Press
ISBN: 9783887631048
Category : Cardiomyopathy
Languages : en
Pages : 188
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Book Description
During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.
Author: Expert Panel on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults (U.S.)
Publisher:
ISBN:
Category : Medical protocols
Languages : en
Pages : 306
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Book Description
Of evidence-based recommendations -- Introduction -- Overweight and obesity: background -- Examination of randomized controlled trial evidence -- Treatment guidelines -- Summary of recommendations -- Future research.
Author: Carmine Izzo
Publisher: Frontiers Media SA
ISBN: 2832539246
Category : Medical
Languages : en
Pages : 175
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Book Description
Metabolic syndrome is a dangerous combination of cardiovascular risk factors that correlate with each other and can increase cardio and cerebrovascular events. The incidence of metabolic syndrome often parallels that of obesity and type 2 diabetes. It is widespread; in the United States, more than 40% of people over the age of 50 have metabolic syndrome. The diagnosis of metabolic syndrome is based on the coexistence of at least three risk factors including waist circumference greater than 102 cm in men or 88 cm in women, systolic blood pressure greater than 130 mmHg and diastolic greater than 85 mmHg, HDL cholesterol less than 40 mg/dl in men or 50 mg/dl in women, triglyceridemia higher than 150 mg/dl and finally fasting glycaemia higher than 110 mg/dl.
Author: T. Barry Levine
Publisher: John Wiley & Sons
ISBN: 1118480074
Category : Medical
Languages : en
Pages : 967
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Book Description
Trends indicate that the metabolic syndrome will become the leading risk factor for heart disease. Now more than ever you need an all-in-one reference that provides the tools and practical advice you need to: Identify at-risk patients Explain individual contributing factors Aid in patient education and motivation Direct comprehensive care and Choose the most appropriate interventions Comprehensively revised to reflect leading-edge research and now organized to facilitate easy access to essential information and clinically-relevant guidance, Metabolic Syndrome and Cardiovascular Disease, 2e offers this and more. Not only will you receive a solid understanding of the pathophysiology underlying the metabolic syndrome and cardiovascular disease but also the rationale for today’s most effective treatments. What’s new? Filled with timely new content, this updated edition covers: New discoveries that have changed our understanding of the pathogenesis and interrelationship of metabolic syndrome, cardiovascular disease (CHD), and type 2 diabetes mellitus (DM) The relevance of mitochondria and telomeres Sleep and its impact on cardiometabolic health The pivotal interplay between insulin and forkhead transcriptionfactors Calorie restriction research Bariatric surgery experiences and outcomes In addition, each chapter includes essential information on comorbidities, interventions, and pharmacotherapeutic options – an exclusive feature found only in the second edition!
Author: Christopher L. Pankey
Publisher:
ISBN: 9780438435308
Category : Cardiovascular system
Languages : en
Pages : 106
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Book Description
Obesity is a growing global issue associated with adverse health consequences including cardiovascular disease, the leading cause of death worldwide. According to the World Health Organization, global obesity has tripled since 1975, and 41 million children under five were obese or overweight in 2016. Sedentary lifestyle and hypercaloric diets are key contributors to increasing incidence of obesity, but there are additional contributing factors to consider. Previous studies from our lab have shown that maternal obesity (OB) predisposes offspring to exhibit indications of the metabolic syndrome including insulin/glucose dysregulation, increased adiposity, hypercortisolemia, and cardiovascular disease. These findings are supported by multiple epidemiologic and controlled animal studies. However, many questions remain regarding in vivo cardiovascular function, and intergenerational programming effects. This dissertation focuses on the intergenerational and transgenerational programming of adverse cardiovascular and metabolic phenotypes from OB. In the first experiment, we evaluated in vivo cardiovascular structure and function using invasive blood pressure measurements, and echocardiography. We found that in prenatal life, OBF1 fetuses have thicker aortas, with a greater collagen:elastin ratio (suggestive of lowered elasticity). We also found that OBF1 are hypertensive relative to CONF1 at 2.5 months of age, yet hypotensive with multiple cardiac geometric changes upon reaching advanced age. These findings suggest that OB programs vascular changes that increase cardiac workload in the young, and eventually leads to indications of cardiac failure in old age. The second and third studies focus on inter- and transgenerational programming of indications for metabolic syndrome after OB. We found that intergenerational programming resulted in OBF2 exhibiting insulin/glucose dysregulation, hypercortisolemia, and increased weight gain when F2 were exposed to a metabolic stress such as ad libitum feed or gestation. We also found that OBF3 show differences in body size and weight at birth, but seemingly normal endocrine profiles. These data suggest that OB programs transgenerational phenotypes that may be epigenetically linked, yet many phenotypes require direct exposure to the initial OBF0 uterine environment. Given the similarities of fetal:maternal mass, temporal pattern of development, and precocial offspring, we suggest that this model is imperative to improving our understanding of obese pregnancies in humans.
Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
ISBN: 1464805202
Category : Medical
Languages : en
Pages : 948
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Book Description
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
Author: Evaristo Fernández Sada
Publisher:
ISBN:
Category :
Languages : es
Pages :
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Book Description
Obesity and metabolic syndrome are associated with significant cardiovascular morbidities. There is growing evidence of the mechanisms involved in their relationship, such as increased risk for diabetes, lipid disorders, metabolic alterations, and inflammation. High levels of circulatig inflammatory mediators, cytokines, have been found in obese subjects and animal models with increased adipose tissue. In turn, cytokines have been long described as mediators of cardiac function, increasing risk for cardiovascular disease and affecting prognosis. We studied 18 obese subjects with no history of cardiovascular disease in order to determine if inflammation was present, and could be altering cardiovascular function.
Author: Gianluca Iacobellis
Publisher: Springer Nature
ISBN: 3030405702
Category : Medical
Languages : en
Pages : 191
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Book Description
This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease. It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease. Comprehensive yet focused, Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030915698X
Category : Medical
Languages : en
Pages : 304
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Book Description
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
