Dihydropyridines

Dihydropyridines PDF Author: Wolf-Dieter Busse
Publisher: Springer Science & Business Media
ISBN: 3642957161
Category : Medical
Languages : en
Pages : 131

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Book Description
This volume reviews important milestones in the history of the development of 1,4-dihydropyridines starting in the late 1960s. The discovery led to theestablishment of Ca2+ antagonists as leading cardiovascular drugs throughoutthe world. This volume includes presentations of the results of some recent collaborative extramural studies by American investigators.

Dihydropyridines

Dihydropyridines PDF Author: Wolf-Dieter Busse
Publisher: Springer Science & Business Media
ISBN: 3642957161
Category : Medical
Languages : en
Pages : 131

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Book Description
This volume reviews important milestones in the history of the development of 1,4-dihydropyridines starting in the late 1960s. The discovery led to theestablishment of Ca2+ antagonists as leading cardiovascular drugs throughoutthe world. This volume includes presentations of the results of some recent collaborative extramural studies by American investigators.

Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists

Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists PDF Author: A. Fleckenstein
Publisher: Springer Science & Business Media
ISBN: 3642704999
Category : Medical
Languages : en
Pages : 520

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Book Description
Held at Boppard, Germany, October 3-6, 1984

Drug-Induced Liver Injury

Drug-Induced Liver Injury PDF Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 288

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Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Hypertension

Hypertension PDF Author: Henry Richard Black
Publisher: Elsevier Health Sciences
ISBN: 1416030530
Category : Medical
Languages : en
Pages : 638

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Book Description
Effectively manage the chronic problems of your hypertensive patients with the practical clinical tools inside Hypertension, 2nd Edition: A Companion to Braunwald's Heart Disease. This respected cardiology reference covers everything you need to know - from epidemiology and pathophysiology through diagnosis, risk stratification, treatment, outcome studies, concomitant diseases, special populations and special situations, and future treatments. Confidently meet the needs of special populations with chronic hypertensive disease, as well as hypertension and concomitant disease. Learn new methods of aggressive patient management and disease prevention to help ensure minimal risk of further cardiovascular problems. Benefit from the authors' Clinical Pearls to reduce complications of hypertension. Use new combination drug therapies and other forms of treatment to their greatest advantage in the management of chronic complications of hypertension. Successfully employ behavior management as a vital part of the treatment plan for hypertensives and pre-hypertensives. Access the complete contents online and download images at www.expertconsult.com. The clinical tools you need to manage hypertension in patients, from the Braunwald family you trust.

The ESC Textbook of Cardiovascular Medicine

The ESC Textbook of Cardiovascular Medicine PDF Author: A. John Camm
Publisher:
ISBN: 9780198824879
Category : Cardiology
Languages : en
Pages : 3198

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Book Description


Privileged Structures in Drug Discovery

Privileged Structures in Drug Discovery PDF Author: Larry Yet
Publisher: John Wiley & Sons
ISBN: 1118686357
Category : Medical
Languages : en
Pages : 562

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Book Description
A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume: Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry Details many of the recent developments in organic chemistry that prepare target molecules Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.

Encyclopedia of Heart Diseases

Encyclopedia of Heart Diseases PDF Author: M. Gabriel Khan
Publisher: Elsevier
ISBN: 008045481X
Category : Medical
Languages : en
Pages : 678

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Book Description
The Encyclopedia of Heart Diseases is an accurate and reliable source of in-depth information on the diseases that kill more than 12 million individuals worldwide each year. In fact, cardiovascular diseases are more prevalent than the combined incidence of all forms of cancer, diabetes, asthma and leukemia. In one volume, this Encylopedia thoroughly covers these ailments and also includes in-depth analysis of less common and rare heart conditions to round out the volume's scope. Researchers, clinicians, and students alike will all find this resource an invaluable tool for quick reference before approaching the primary literature. * Coverage of more than 200 topics, including: applied pharmacology of current and experimental cardiac drugs, gene therapy, MRI, electron-beam CT, PET scan put in perspective, cardiac tests costs and justification, and new frontiers in cardiovascular research* More than 150 helpful figures and illustrations!* Dr. Khan is a well-published and respected expert in heart and heart diseases

Ventricular Arrhythmias

Ventricular Arrhythmias PDF Author: John M. Miller
Publisher:
ISBN: 9781416062752
Category : Arrhythmia
Languages : en
Pages : 0

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Book Description
Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.

Cardiovascular Disability

Cardiovascular Disability PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030915698X
Category : Medical
Languages : en
Pages : 304

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Book Description
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.

Dihydropyridines and Macrocyclic Rings

Dihydropyridines and Macrocyclic Rings PDF Author: Coos Bram Troostwijk
Publisher:
ISBN:
Category :
Languages : en
Pages : 116

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Book Description