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Author: K. Musshoff
Publisher:
ISBN: 9783642808302
Category :
Languages : en
Pages : 268
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Book Description
Author: K. Musshoff
Publisher:
ISBN: 9783642808302
Category :
Languages : en
Pages : 268
Get Book
Book Description
Author: K. Musshoff
Publisher: Springer Science & Business Media
ISBN: 3642808298
Category : Medical
Languages : en
Pages : 301
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Book Description
K. MUSSHOFF The group of diseases known as malignant lymphomas are, for a number of reasons, of equal interest to theoretical and clinical medicine. New findings in the fields of virology and immunology could conceivably shed some light on the so far unknown etiology of malignant lymphomas. A viral etiology could explain many of the dis parate findings with such a puzzling disease as lymphogranulomatosis, which shows both all the signs of malignancy, such as the characteristic Reed-Sternberg and Hodgkin cells and chromosome abnormalities, and those of an inflammatory disease, i.e. typical changes in the blood count and bone marrow and in the distribution of serum proteins. So far we have not been able to identify the etiology of this disease. However, clinical observations and pathomorphological investigations involving a joint effort by different branches of medicine have brought us closer to an understanding of the clinical picture. Descriptive anatomy has given us a clear picture of the regional distribution of the lymphatic system, which has long been neglected in the past. The introductory paper by Dr. S. KUBIK (Zurich), who has made valuable contributions to our knowl edge of the anatomy of the lymphatic system, deals with this subject.
Author: Anas Younes
Publisher: Springer Science & Business Media
ISBN: 1627034080
Category : Medical
Languages : en
Pages : 414
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Book Description
Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.
Author: Bruce W. Dana
Publisher: Springer Science & Business Media
ISBN: 1461530849
Category : Medical
Languages : en
Pages : 248
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Book Description
This volume is intended to present an eclectic selection of informative reviews on aspects of the malignant lymphomas, including Hodgkin's disease. The choice of suitable review topics in this field is made hazardous by several facts. First, the growth of insight into basic mechanisms of lymphomagenesis is explosive, as is the expansion of our understanding of the need for precise morphologic classification of these diseases. Second, new therapeutic agents, cytotoxic and biologic, as well as new drug delivery strategies, are appearing with remarkable frequency. Finally, old "standard" approaches, such as the staging laparotomy for Hodgkin's disease, are being reconsidered and deserve attention in an up-to-date collection of papers. The 10 reviews presented here fall generally into three categories. First, the optimal diagnostic and therapeutic approaches to Hodgkin's disease are considered by Mark Leibenhaut, who reviews the status of the diagnostic staging laparotomy, and by Philip Bierman, who discusses his thoughts on the timing of high-dose treatment with bone marrow transplantation for this disease. There follow four reviews of current management of specific histologic subtypes of malignant lymphoma. First, Velasquez reviews prognostic factors in both intermediate and high grade lymphomas. Miller and Dahlberg review and update the Southwest Oncology Group experience in developing curative cytotoxic combination therapies for diffuse large-cell lymphomas. Lastly, optimal therapy for two kinds of high grade lymphoma are presented. Butler and Hainsworth describe the Vanderbilt experience with diffuse small noncleaved cell lymphoma and Picozzi reviews lymphoblastic lymphoma.
Author: Andrew M. Evens
Publisher: Springer
ISBN: 3319131508
Category : Medical
Languages : en
Pages : 344
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Book Description
This book provides clinical practitioners and the research community with detailed information on the diagnosis, prognosis, and treatment of non-Hodgkin lymphoma, taking into account the significant growth in knowledge including multiple therapeutic advances that have been achieved over the past 5-10 years. The work is subdivided into epidemiology, pathogenesis, pathology, imaging, and therapy of the non-Hodgkin lymphomas. The full range of therapeutic options are examined according to the major subtypes of non-Hodgkin lymphoma and the most up-to-date information is provided on current standard treatment options, including stem cell transplantation as well as new cutting-edge therapeutics.
Author: Wendy N. Erber
Publisher: CRC Press
ISBN: 9783718650583
Category : Lymphomas
Languages : en
Pages : 232
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Book Description
Contains comprehensive reviews and illustrated case presentations on the pathological classification, molecular and immunological features and diagnosis of this group of malignancies. Featuring chapters by five leading international experts: *Karl Lennert *Robert J. Lukes *Bharat N. Nathwani *Taizan Suchi *Dennis H. Wright
Author: D. W. Molander
Publisher: Springer Science & Business Media
ISBN: 1461251982
Category : Medical
Languages : en
Pages : 357
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Book Description
This volume presents a practical approach for clinicians who work with patients afflicted with diseases of the lymphoid system and bone marrow. Associated biochemical, hematological, and chromosomal abnormalities, as well as infectious complications, are covered because of their importance in managing patients with lymphatic diseases. In addition, cell kinetics and the classification of lym phocytic lymphomas are included because familiarity with these subjects leads to a better understanding of the physiology of the disease. Radiological techniques that aid the clinician in the diagnosis and management of diseases of the lymphoid tissue are discussed. The explosive interest in patients with generalized acquired (auto) immune deficiency syndrome (AIDS) prompted the inclusion of a chapter exclusively devoted to this topic. Finally, the chapter dealing with psychological aspects of patients with cancer allows the reader to become familiar with useful techniques. Distilled from a vast array of data and representing the most up-to-date material available, this volume is intended to be of interest to internists, oncolo gists, hematologists, radiotherapists, nurses, and anyone in an associated pa ramedical field who may be involved in the care of patients with diseases of the lymphatic system. Acknowledgements: I am indebted to the following for their help in making this volume possible: Mr. Rudy De Angelo and the Hudson County Chapter of the Pack Medical Foundation, Mrs. Louis Berkoff, Mrs. Frances Goldman, The Pack Medical Foundation, Mr. and Mrs. Julius Schure and Mr. Richard Schure. DAVID W. MOLANDER, M.D.
Author: James O. Armitage
Publisher: Lippincott Williams & Wilkins
ISBN: 1469837315
Category : Medical
Languages : en
Pages : 656
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Book Description
Thoroughly updated for its Second Edition, Non-Hodgkin Lymphomas is the definitive textbook on the biology, diagnosis, staging, and treatment of all forms of non-Hodgkin lymphomas. With backgrounds in medical and radiation oncology, molecular biology, and pathology, the editors and contributors provide an international, multidisciplinary approach to the topic. This edition is the first text using the new World Health Organization classification of non-Hodgkin lymphomas. The book offers complete coverage of the most current techniques for diagnosis, staging, and treatment, the approach to specific types of lymphoma, and special problems common to the management of patients with these disorders.
Author: M. L. Jacobs
Publisher: Springer Science & Business Media
ISBN: 3642999506
Category : Medical
Languages : en
Pages : 56
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Book Description
Over the years, the management of lymphomatous disease has followed a general trend from the purely empirical and intuitive use of medications to radiation, to surgery, and to chemotherapy with alkylating agents and anti-metabolites. In the 20th century, the treatment of these diseases has been predominantly by radiation. As radiology emerged from ROENTGEN'S original work to the sophisticated science of the present, the radiological equipment, which had been crude and inaccurate, evolved into mechanical and electronic instruments of enormous complexity and capable of great accuracy. The progress and success of radiation therapy for malig nant disease paralleled the technical development of the devices employed. For this reason, the chronology of the parallel development is given in detail. The gross and histologic descriptions of the lymphomas, from 1832 to the present, are voluminous and controversial. Therefore the pathology is reviewed and these diseases classified before reviewing therapy of the lymphomas. I. Hodgkin's Disease 1. Pathology and Classification The current classification of the so-called lymphomata into HODGKIN'S disease, lymphosarcoma, and reticulum cell sarcoma is modern. Any historical or scientific review of ,the subject rightfully begins with a discussion of HODGKIN'S original paper entitled "On Some Morbid Appearances of the Absorbent Glands and Spleen" published in 1832. This classical report describes the clinical and gross pathologic findings in a group of patients whose symptomatology presented striking similarities; notably enlargement of peripheral lymph nodes in the neck, the axillae, and the groin and, frequently, enlargement of the mediastinal nodes.
Author: John P. Leonard
Publisher: Springer Science & Business Media
ISBN: 0387293469
Category : Medical
Languages : en
Pages : 475
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Book Description
In recent years a dramatic increase in knowledge of the biology of the lymphomas has been accompanied by the emergence of new treatments offering improvements in efficacy and reduction in toxicity. In this volume an internationally recognized group of experts review relevant aspects of the biology, diagnosis and management, with particular emphasis on the emerging data available for this disease.
