Developmental Quantitative Genetics of Drosophila Melanogaster

Developmental Quantitative Genetics of Drosophila Melanogaster PDF Author: David Earl Cowley
Publisher:
ISBN:
Category :
Languages : en
Pages : 326

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Developmental Quantitative Genetics of Drosophila Melanogaster

Developmental Quantitative Genetics of Drosophila Melanogaster PDF Author: David Earl Cowley
Publisher:
ISBN:
Category :
Languages : en
Pages : 326

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Quantitative genetic variation

Quantitative genetic variation PDF Author: James N. Jr. Thompson
Publisher: Elsevier
ISBN: 0323156029
Category : Science
Languages : en
Pages : 327

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Book Description
Quantitative Genetic Variation describes some of the experimental approaches to quantitative genetic variation, along with their potential applications and limitations. It considers one of the most widely applicable tools, i.e., biometrical analysis, as well as individual polygenic effects, specific components of a quantitative genetic trait, and artificial selection, and it shows how selection experiments can address specific developmental and genetic questions. Organized into four sections encompassing 17 chapters, this volume begins with a historical overview of the study of quantitative genetic variation, along with genetic variation in fungi and Drosophila. It then discusses the biometrical approach to quantitative variation, selection theory and analysis, uses and limitations of polygene mapping, and computer simulation of the breeding program for polygene location. The reader is also introduced to genes affecting quantitative aspects of physiology in rodents, as well as cytological markers and quantitative variation in wheat. This book will be extremely useful to students, researchers, and geneticists.

Quantitative Developmental Genetics of Biological Stability in Drosophila Melanogaster [microform]

Quantitative Developmental Genetics of Biological Stability in Drosophila Melanogaster [microform] PDF Author: Ian Michael Dworkin
Publisher: Library and Archives Canada = Bibliothèque et Archives Canada
ISBN: 9780612945395
Category :
Languages : en
Pages : 526

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Biological stability at the level of individual organisms is reflected in the nature and degree of variation observed in phenotypic traits. In this thesis, I examine properties of biological stability within the framework of canalization of a number of morphological traits in Drosophila melanogaster. I employ a combination of both genetic and environmental perturbations to explore various measures of stability in the sternopleural bristle system, and on the pro-thoracic leg. Furthermore, I utilize the techniques from developmental genetics to explore the temporal aspects of trait stability and sensitivity using the antenna to leg homeotic transformation as a model system.

The Developmental Basis of Quantitative Genetic Variation Revealed by the Maize Mutant, Polymitotic

The Developmental Basis of Quantitative Genetic Variation Revealed by the Maize Mutant, Polymitotic PDF Author: David Paul West
Publisher:
ISBN:
Category :
Languages : en
Pages : 264

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Developmental Behavior Genetics

Developmental Behavior Genetics PDF Author: Martin E. Hahn
Publisher: Oxford University Press, USA
ISBN:
Category : Political Science
Languages : en
Pages : 358

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Book Description
Behavior genetics, the study of how genes regulate developmental changes in behavior, draws together experimental research in molecular and quantitative genetics, neurobiology, and developmental psychology. This new volume includes contributions from leading experts who bring readers the benefit of their experience in many diverse areas by examining current theory and methods and by suggesting directions for future research. The book takes a unique interdisciplinary approach, focusing on the integration of development into the study of behavior, the role of genes in the construction of the nervous system, and the role of natural selection in shaping developing behaviors. Many chapters deal directly with methodological and quantitative issues, providing detailed study of the interactive roles of genes, environment, and development, and placing them within the context of current evolutionary thinking.

Evolutionary Quantitative Genetics

Evolutionary Quantitative Genetics PDF Author: Stevan J. Arnold
Publisher: Oxford University Press
ISBN: 0192859382
Category : Literary Criticism
Languages : en
Pages : 497

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Book Description
Evolutionary quantitative genetics (EQG) provides a formal theoretical foundation for quantitatively linking natural selection and genetic variation to the rate and expanse of adaptive evolution. It has become the dominant conceptual framework for interpreting the evolution of quantitative traits in terms of elementary forces (mutation, inheritance, selection, and drift). Despite this success, the relevance of EQG to many biological scenarios remains relatively unappreciated, with numerous fields yet to fully embrace its approach. Part of the reason for this lag is that conceptual advances in EQG have not yet been fully synthesized and made accessible to a wider academic audience. A comprehensive, accessible overview is therefore now timely, and Evolutionary Quantitative Genetics provides this much-needed synthesis. The central argument of the book is that an adaptive landscape concept can be used to understand both evolutionary process within lineages and the pattern of adaptive radiations. In particular, it provides a convincing argument that models with a moving adaptive peak carry us further than any other conceptual approach yet devised. Although additive theory holds center stage, the book mentions and references departures from additivity including non-Gaussian distributions of allelic effects, dominance, epistasis, maternal effects and phenotypic plasticity. This accessible, advanced textbook is aimed principally at students (from senior undergraduate to postgraduate) as well as practising scientists in the fields of evolutionary biology, ecology, physiology, functional morphology, developmental biology, comparative biology, paleontology, and beyond who are interested in how adaptive radiations are produced by evolutionary and ecological processes.

The Development of Drosophila Melanogaster

The Development of Drosophila Melanogaster PDF Author: Michael Bate
Publisher:
ISBN:
Category : Drosophila melanogaster
Languages : en
Pages : 766

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Molecular Quantitative Genetics of Wing Shape in Drosophila Melanogaster

Molecular Quantitative Genetics of Wing Shape in Drosophila Melanogaster PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
Building on quantitative genetic analysis in fruitflies I chose to investigate the molecular genetic underpinnings of natural variation in wing shape. Shape is a complex trait demanding a multidimensional description and was adequately portrayed and quantified with the tools of morphometrics. The results demonstrate uncoupling of size and shape. Shape shows strong degree of integration over the structure, disputing hypothesis of the wing as comprised of independent modules laid down by compartmentalization. However, distinctly local shape effects are also observed in genetic correlations, complementation and association tests, arguing for a continuous distribution along an axis of integration and modularity. The identification of quantitative trait nucleotides within a QTL was pursed in a two step scheme. First I tested a set of candidate loci, implicated by QTL experiments and/or developmental roles, for contribution to wing shape. The results are consistent with segregating variation of loci in the vein-determining pathways, hedgehog (hh), decapentaplegic (dpp) and Epidermal growth factor Receptor (EGFR), impacting shape. The second step involved fine-scale mapping, by testing for associations between EGFR and wing shape in two geographic populations of D. melanogaster. The genotyping was done by sequencing 10.9 kb of the locus from 209 lines demonstrating a mostly neutral locus, possibly experiencing purifying selection. One of two alternate 5'-exons may be evolving more rapidly by positive directional selection. Linkage disequilibrium decays rapidly within EGFR increasing the resolution of association mapping. Association tests identified one site (C31365T) with sex dependent effects on wing size, significant after Bonferroni correction. Seven more sites are weakly suggested. The highest of those (C30200T) disrupts a putative GAGA factor binding element and has replicable effects on crossvein placement in three study designs. The work suggests naturally occurrin.

Quantitative Genetics in the Wild

Quantitative Genetics in the Wild PDF Author: Anne Charmantier
Publisher: Oxford University Press
ISBN: 019967423X
Category : Medical
Languages : en
Pages : 293

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Book Description
This book gathers the expertise of 30 evolutionary biologists from around the globe to highlight how applying the field of quantitative genetics - the analysis of the genetic basis of complex traits - aids in the study of wild populations.

Developmental and Genetic Mechanisms of Ovariole Number Evolution in Drosophila

Developmental and Genetic Mechanisms of Ovariole Number Evolution in Drosophila PDF Author: Delbert Green
Publisher:
ISBN:
Category :
Languages : en
Pages :

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