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Author: Vassilios Fanos
Publisher: Hygeia Press
ISBN: 8890651407
Category : Medical
Languages : en
Pages : 272
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Book Description
The traditional approach to kidney disorders is changing. In the field of diagnostics much innovative research is ongoing: from the “old” embryology, revisited and re-interpreted with new eyes in the light of immunohistochemistry, up to metabolomics the latest “daughter” of genomics, the most promising and remarkable of the “omics” disciplines. Between these two extremes we find a universe of novelties, ranging from the most recent urinary biomarkers to the questions of nutrition and growth, as well as those of ethics, which the new populations of extremely low birth weight (ELBW) neonates present to neonatologists and nephrologists. The studies on perinatal programming expands the temporal horizon of precocious reduction in the number of nephrons, both congenital and/or acquired, thus dilating and multiplying the immediate and long-term negative effects. Neonatal asphyxia, obstructive uropathies, nephrotoxic drugs administered to the mother and/or to the neonate, malnutrition, underfeeding, or overfeeding make it necessary to apply all possible preventive measures to ensure the well-being of the kidney. Because of the kidney’s holistic dimension, themethodical and rigorous study of neonatal nephrology has advanced all aspects of health through the life cycle. This volume is an update state of the art of the latest discoveries in neonatal and pediatric nephrology. These advances will have an even greater impact when the same children reach adulthood, and the ultimate consequences of perinatal care are unmasked.
Author: Vassilios Fanos
Publisher: Hygeia Press
ISBN: 8890651407
Category : Medical
Languages : en
Pages : 272
Get Book Here
Book Description
The traditional approach to kidney disorders is changing. In the field of diagnostics much innovative research is ongoing: from the “old” embryology, revisited and re-interpreted with new eyes in the light of immunohistochemistry, up to metabolomics the latest “daughter” of genomics, the most promising and remarkable of the “omics” disciplines. Between these two extremes we find a universe of novelties, ranging from the most recent urinary biomarkers to the questions of nutrition and growth, as well as those of ethics, which the new populations of extremely low birth weight (ELBW) neonates present to neonatologists and nephrologists. The studies on perinatal programming expands the temporal horizon of precocious reduction in the number of nephrons, both congenital and/or acquired, thus dilating and multiplying the immediate and long-term negative effects. Neonatal asphyxia, obstructive uropathies, nephrotoxic drugs administered to the mother and/or to the neonate, malnutrition, underfeeding, or overfeeding make it necessary to apply all possible preventive measures to ensure the well-being of the kidney. Because of the kidney’s holistic dimension, themethodical and rigorous study of neonatal nephrology has advanced all aspects of health through the life cycle. This volume is an update state of the art of the latest discoveries in neonatal and pediatric nephrology. These advances will have an even greater impact when the same children reach adulthood, and the ultimate consequences of perinatal care are unmasked.
Author: Gavino Faa
Publisher: Springer
ISBN: 1493909479
Category : Medical
Languages : en
Pages : 115
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Book Description
This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.
Author: Rachel K. Miller
Publisher: Springer
ISBN: 3319514369
Category : Science
Languages : en
Pages : 373
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Book Description
Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.
Author: Wallace W. McCrory
Publisher: Harvard University Press
ISBN: 9780674202757
Category : Embryology, Human
Languages : en
Pages : 274
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Book Description
"It is my hope," writes the author in his preface, "that the material collected in this monograph will provide a new perspective in some areas for those students, biologists, and physicians interested in the kidney but too involved with their special trees to notice some of the changes occurring in the forest in which they toil." In the first up-to-date compendium to correlate the changes in kidney structure and function from the onset of organogenesis to the end of childhood growth, Dr. Wallace McCrory presents a new aspect of developmental pediatrics, skillfully explains the clinical enigmas surrounding the immature kidney, and suggests possible research areas for productive exploration. Clearly documented with tables and illustrations, the study synthesizes relevant new knowledge from the fields of embryology, biochemistry, and renal and growth physiology as a means of stimulating reappraisals of the current concepts of the pathophysiology of many childhood renal diseases. Included are reproductions of reconstructed micro dissections of the early stages in the developing human kidney taken from Dr. Jean Oliver's monograph Nephrons and Kidneys.
Author: Sunil Kochhar
Publisher: Springer
ISBN: 144716539X
Category : Medical
Languages : en
Pages : 389
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Book Description
This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.
Author:
Publisher: Academic Press
ISBN: 0123944198
Category : Science
Languages : en
Pages : 275
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Book Description
Volume 58 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology. - Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology
Author: John N van den Anker
Publisher: Elsevier Health Sciences
ISBN: 1455747386
Category : Medical
Languages : en
Pages : 255
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Book Description
The need for safe and effective use of medicines in children and WHO's initiative "Make Medicines Child Size" have boosted research and educational activities in the area of pediatric clinical drug research. This issue focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics. The editors have been able to find outstanding authors for the different parts on neonatal and pediatric pharmacology.
Author:
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 2035
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Book Description
Author: Vassilios Fanos
Publisher: Hygeia Press
ISBN: 8898636431
Category : History
Languages : en
Pages : 237
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Book Description
The leading elements in this volume are the cultural representation of birth and the forms through which its narration and representation develop in the figurative arts, through historical references, mythological tales and legends, traditions, customs and habits. The influence of myth, language and artistic expression on our cultural representation of procreation is manifest, and this way of “narrating” birth resists even today, although it comes into conflict with a more scientific vision of pregnancy and childbirth. With this book we believe we have contributed to an in-depth examination of illness narratives, thus favouring the search for a convergence between medical language in the sector and the language of cultural experience so that evidence-based medicine does not clash with narrative-based medicine, but that the two languages come together towards a reciprocity that will strengthen the alliance between physician and patient.
Author: Odyss Michos
Publisher: Humana Press
ISBN: 9781493962556
Category : Medical
Languages : en
Pages : 432
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Book Description
Reflecting recent revolutionary advances in our understanding of renal development, this volume details step-by-step protocols researchers can deploy in their own work, including 3-D morphogenetic mapping and assessing kidney malformation and morbidity.
