Developmental Genetics of the Pharyngeal Arch System

Developmental Genetics of the Pharyngeal Arch System PDF Author: Jeffry M. Cesario
Publisher: Biota Publishing
ISBN: 161504681X
Category : Science
Languages : en
Pages : 120

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Book Description
The pharyngeal arches are embryonic structures that develop into the face, neck, a part of the heart, and several endocrine glands in animals. They are thought to have played a key role in vertebrate evolution as their derivatives impact the mode of feeding and breathing. Moreover, perturbation in pharyngeal arch development is associated with several major groups of birth defects in humans. During early embryonic development, cells from all three germ layers come together to assemble the pharyngeal arches. Subsequently, the pharyngeal arches undergo growth, morphogenesis, and cell type differentiation to give rise to musculoskeletal, cardiovascular, neural, and glandular components. These processes are guided by interactions amongst different tissues, via signaling molecules. A large number of genes, with a complex network of regulatory relationships, govern each aspect of pharyngeal arch development. With the advance of molecular genetics tools in model organisms such as mice, we are beginning to understand the molecular and cellular mechanisms underlying development of the pharyngeal arches and related birth defects. This eBook will provide an introduction into development of the pharyngeal arch system, with a detailed discussion on the genetic regulation of this process.

Developmental Genetics of the Pharyngeal Arch System

Developmental Genetics of the Pharyngeal Arch System PDF Author: Jeffry M. Cesario
Publisher: Biota Publishing
ISBN: 161504681X
Category : Science
Languages : en
Pages : 120

Get Book Here

Book Description
The pharyngeal arches are embryonic structures that develop into the face, neck, a part of the heart, and several endocrine glands in animals. They are thought to have played a key role in vertebrate evolution as their derivatives impact the mode of feeding and breathing. Moreover, perturbation in pharyngeal arch development is associated with several major groups of birth defects in humans. During early embryonic development, cells from all three germ layers come together to assemble the pharyngeal arches. Subsequently, the pharyngeal arches undergo growth, morphogenesis, and cell type differentiation to give rise to musculoskeletal, cardiovascular, neural, and glandular components. These processes are guided by interactions amongst different tissues, via signaling molecules. A large number of genes, with a complex network of regulatory relationships, govern each aspect of pharyngeal arch development. With the advance of molecular genetics tools in model organisms such as mice, we are beginning to understand the molecular and cellular mechanisms underlying development of the pharyngeal arches and related birth defects. This eBook will provide an introduction into development of the pharyngeal arch system, with a detailed discussion on the genetic regulation of this process.

Principles of Developmental Genetics

Principles of Developmental Genetics PDF Author: Sally A. Moody
Publisher: Academic Press
ISBN: 0124059236
Category : Science
Languages : en
Pages : 773

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Book Description
Providing expert coverage of all major events in early embryogenesis and the organogenesis of specific systems, and supplemented with representative clinical syndromes, Principles of Developmental Genetics, Second Edition discusses the processes of normal development in embryonic and prenatal animals, including humans. The new edition of this classic work supports clinical researchers developing future therapies with its all-new coverage of systems biology, stem cell biology, new technologies, and clinical disorders. A crystal-clear layout, exceptional full-color design, and bulleted summaries of major takeaways and clinical pathways assist comprehension and readability of the highly complex content. - All-new coverage of systems biology and stem cell biology in context of evolving technologies places the work squarely on the modern sciences - Chapters are complemented with a bulleted summary for easy digestion of the major points, with a clinical summary for therapeutic application - Clinical highlights provides a bridge between basic developmental biology and clinical sciences in embryonic and prenatal syndromes

Craniofacial Development

Craniofacial Development PDF Author: Peter Thorogood
Publisher:
ISBN:
Category : Facial bones
Languages : en
Pages : 0

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Book Description


The Neural Crest

The Neural Crest PDF Author: Nicole Le Douarin
Publisher: Cambridge University Press
ISBN: 9780521620109
Category : Medical
Languages : en
Pages : 494

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Book Description
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Kaufman's Atlas of Mouse Development Supplement

Kaufman's Atlas of Mouse Development Supplement PDF Author: Gillian Morriss-Kay
Publisher: Elsevier
ISBN: 0443237387
Category : Science
Languages : en
Pages : 668

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Book Description
Kaufman's Atlas of Mouse Development Supplement, Second Edition continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems. The book explores the developmental origins of the organ systems, following the original atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. In this new edition, each chapter has been updated to include the latest research, along with while new chapters on the functional aspects of mouse and human heart development, the immune system, and the inner ear. These additions ensure an up-to-date resource for all biomedical scientists who use the mouse as a model species for understanding the normal and abnormal development of human systems. - Offers in-depth anatomy and morphological views of organ systems and their developmental origins - Includes the latest techniques for visualizing gene expression and other functional aspects of tissue and organ development - Explores the links between mouse and human developmental processes - Features high-quality color images to help readers visualize key developmental processes and structures

Neural Crest and Placodes

Neural Crest and Placodes PDF Author:
Publisher: Academic Press
ISBN: 0124078907
Category : Science
Languages : en
Pages : 573

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Book Description
Neural Crest and Placodes provides in-depth coverage of the topic, including information on their critical role in vertebrate development, evolution, and the way defects in their development underlie a wide range of congenital disorders. It delves deep into advances made in our understanding of the mechanisms governing the formation, migration, and differentiation of these two cell populations, also discussing their integration during embryonic development. The text highlights the application of fundamental knowledge in investigating the etiology and pathogenesis of congenital disorders and the ways the data applies to the field of regenerative medicine. - Written by leading experts in the field - Includes descriptions of the most recent advances in the field - Highlights the applications of this knowledge in investigating the etiology and pathogenesis of congenital disorders - Explores their usage in the field of regenerative medicine

Evolution and Development of Fishes

Evolution and Development of Fishes PDF Author: Zerina Johanson
Publisher: Cambridge University Press
ISBN: 1107179440
Category : Nature
Languages : en
Pages : 283

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Book Description
World-class palaeontologists and biologists summarise the state-of-the-art on fish evolution and development.

The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research PDF Author: Samuel Cartner
Publisher: Academic Press
ISBN: 0128124326
Category : Science
Languages : en
Pages : 720

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Book Description
The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. - Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications - Includes the work of world-renowned authors - Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Netter's Atlas of Neuroscience

Netter's Atlas of Neuroscience PDF Author: David L. Felten
Publisher: Elsevier Health Sciences
ISBN: 0323265111
Category : Medical
Languages : en
Pages : 499

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Book Description
Ideal for students of neuroscience and neuroanatomy, the new edition of Netter's Atlas of Neuroscience combines the didactic well-loved illustrations of Dr. Frank Netter with succinct text and clinical points, providing a highly visual, clinically oriented guide to the most important topics in this subject. The logically organized content presents neuroscience from three perspectives: an overview of the nervous system, regional neuroscience, and systemic neuroscience, enabling you to review complex neural structures and systems from different contexts. You may also be interested in: A companion set of flash cards, Netter's Neuroscience Flash Cards, 3rd Edition, to which the textbook is cross-referenced. Coverage of both regional and systemic neurosciences allows you to learn structure and function in different and important contexts. Combines the precision and beauty of Netter and Netter-style illustrations to highlight key neuroanatomical concepts and clinical correlations. Reflects the current understanding of the neural components and supportive tissue, regions, and systems of the brain, spinal cord, and periphery. Uniquely informative drawings provide a quick and memorable overview of anatomy, function, and clinical relevance. Succinct and useful format utilizes tables and short text to offer easily accessible "at-a-glance" information. Provides an overview of the basic features of the spinal cord, brain, and peripheral nervous system, the vasculature, meninges and cerebrospinal fluid, and basic development. Integrates the peripheral and central aspects of the nervous system. Bridges neuroanatomy and neurology through the use of correlative radiographs. Highlights cross-sectional brain stem anatomy and side-by-side comparisons of horizontal sections, CTs and MRIs. Features video of radiograph sequences and 3D reconstructions to enhance your understanding of the nervous system. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, 14 videos, and images from the book. Expanded coverage of cellular and molecular neuroscience provides essential guidance on signaling, transcription factors, stem cells, evoked potentials, neuronal and glial function, and a number of molecular breakthroughs for a better understanding of normal and pathologic conditions of the nervous system. Micrographs, radiologic imaging, and stained cross sections supplement illustrations for a comprehensive visual understanding. Increased clinical points -- from sleep disorders and inflammation in the CNS to the biology of seizures and the mechanisms of Alzheimer's -- offer concise insights that bridge basic neuroscience and clinical application.

Genetic Diversity and Disease Susceptibility

Genetic Diversity and Disease Susceptibility PDF Author: Yamin Liu
Publisher: BoD – Books on Demand
ISBN: 1789842018
Category : Medical
Languages : en
Pages : 166

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Book Description
Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.