Author: David A. Blizard
Publisher: Elsevier Science & Technology
ISBN:
Category : Hypertension
Languages : en
Pages : 720
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Book Description
Hardbound. The present volume of the Handbook of Hypertension draws together knowledge on the endogenous (genetic) and exogenous (environmental) components contributing to the pathogenesis of essential hypertension. In the field of hypertension research, the importance of adopting a genetic approach to its phenomenology was recognized at an early stage. There was early debate concerning the nature of the genetic architecture underlying population variability in blood-pressure but today its polygenic nature is generally accepted and is reflected in the design and orientation of human investigations as well as in the heterogeneity of mechanisms that have been unearthed by exploration with diverse animal genetic models. Concurrently, epidemiological studies have emphasized the contribution of a variety of environmental factors in the etiology of hypertension. In particular, the contribution of dietary factors, smoking and lifestyle to the develop
Author:
Publisher:
ISBN: 9780444903419
Category : Hypertension
Languages : en
Pages : 693
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Book Description
Author:
Publisher:
ISBN: 9780444903419
Category :
Languages : en
Pages : 693
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Book Description
Author:
Publisher:
ISBN:
Category : Hypertension
Languages : en
Pages : 0
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Book Description
Author:
Publisher:
ISBN: 9780444903419
Category :
Languages : en
Pages : 693
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Book Description
Author:
Publisher:
ISBN: 9780444903419
Category :
Languages : en
Pages :
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Book Description
Author: Anna F. Dominiczak
Publisher: Elsevier Health Sciences
ISBN: 0444514562
Category : Medical
Languages : en
Pages : 284
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Book Description
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
Author: David A. Blizard
Publisher: Elsevier Science & Technology
ISBN:
Category : Medical
Languages : en
Pages : 726
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Book Description
Hardbound. The present volume of the Handbook of Hypertension draws together knowledge on the endogenous (genetic) and exogenous (environmental) components contributing to the pathogenesis of essential hypertension. In the field of hypertension research, the importance of adopting a genetic approach to its phenomenology was recognized at an early stage. There was early debate concerning the nature of the genetic architecture underlying population variability in blood-pressure but today its polygenic nature is generally accepted and is reflected in the design and orientation of human investigations as well as in the heterogeneity of mechanisms that have been unearthed by exploration with diverse animal genetic models. Concurrently, epidemiological studies have emphasized the contribution of a variety of environmental factors in the etiology of hypertension. In particular, the contribution of dietary factors, smoking and lifestyle to the develop
Author: Alexander Heazell
Publisher: Cambridge University Press
ISBN: 1139490869
Category : Medical
Languages : en
Pages :
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Book Description
Hypertensive disorders are among the most common medical complications of pregnancy, with an incidence of approximately 6-10%. This spectrum of conditions includes essential hypertension, pre-eclampsia and HELLP syndrome. For patients with pre-existing hypertension, management ideally commences prior to conception, and continues through pregnancy to the postnatal period. This book provides information on the evidence-based management of women with hypertension throughout pregnancy, supported by important background information on the etiology, risk-factors and pathophysiology of these disorders. Illustrated with accompanying algorithms, tables and lists for quick reference on diagnostic criteria, drugs and side-effects, this book will help clinicians rapidly gain access to the information they need to care for these patients. This will to be of interest to all grades of obstetric trainees as well as specialists, obstetric anesthetists and anesthetic trainees, midwives and maternal-fetal physicians.
Author: Adel E. Berbari
Publisher: Springer
ISBN: 3319599186
Category : Medical
Languages : en
Pages : 858
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Book Description
This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.
