Development of Novel Multi-dimensional Separation Based Instrumentation and Data Analysis Strategies for Complex Samples

Development of Novel Multi-dimensional Separation Based Instrumentation and Data Analysis Strategies for Complex Samples PDF Author: W. Christopher Siegler
Publisher:
ISBN:
Category : Multidimensional chromatography
Languages : en
Pages : 153

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Multi-dimensional Separations and Data Analysis Technologies for the Elucidation of Information from Complex Samples

Multi-dimensional Separations and Data Analysis Technologies for the Elucidation of Information from Complex Samples PDF Author: Elizabeth M. Humston
Publisher:
ISBN:
Category : Chemistry, Analytic
Languages : en
Pages : 281

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Multidimensional Analytical Techniques in Environmental Research

Multidimensional Analytical Techniques in Environmental Research PDF Author: Regina Duarte
Publisher: Elsevier
ISBN: 0128188979
Category : Science
Languages : en
Pages : 316

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Book Description
Multidimensional Analytical Techniques in Environmental Research is a comprehensive resource on the many multidimensional analytical strategies to qualitatively and quantitatively assess and map the organic and inorganic pollutants in complex atmospheric, water and soil matrices. During the past two decades, the rapidly-evolving field of analytical instrumentation has produced sophisticated multidimensional tools capable of providing unique and in-depth knowledge on the chemical features of complex mixtures from these different environmental matrices. This book brings together the wealth of information in the current literature, assisting in the decision-making process by covering both the fundamentals and applications of these methodologies. Sections cover the wide variety of multidimensional analytical techniques, including multidimensional solution- and solid-state nuclear magnetic resonance (NMR) spectroscopy, ultrahigh-resolution mass spectrometry (MS), two-dimensional correlation spectroscopy, two-dimensional liquid and gas chromatography and capillary electrophoresis coupled to high-resolution detection techniques, and excitation-emission (EEM) fluorescence spectroscopy assisted by multiway data analysis tools, and the use of synchrotron-radiation-based techniques combined with other spectroscopic approaches to explore and map the speciation of elements. - Identifies state-of-the-art multidimensional analytical methods for targeted and untargeted profiling of complex mixtures from different environmental matrices (soil, sediment, water, and air) - Assesses the advantages and limitations of the most modern and sophisticated multidimensional analytical methods in environmental research - Highlights the current challenges and potential future directions in the application of multidimensional analytical tools to advance the current understanding on the dynamics and fate of environmental pollutants in different environmental matrices

Development of Alternative Green Sample Preparation Techniques

Development of Alternative Green Sample Preparation Techniques PDF Author: Emanuela Gionfriddo
Publisher: MDPI
ISBN: 3039434683
Category : Science
Languages : en
Pages : 230

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Book Description
The Special Issue of Separations, “Development of Alternative Green Sample Preparation Techniques”, provides an overview on recent trends in green sample preparation. This Special Issue of Separations collates 11 impressive contributions that describe the state-of-the-art in the development of green extraction technologies, from green materials for microextraction to the development of new sampling devices geometries for enhanced extraction efficiency and analysis throughput.

Mass Spectrometry for Lipidomics

Mass Spectrometry for Lipidomics PDF Author: Michal Holcapek
Publisher: John Wiley & Sons
ISBN: 3527836500
Category : Science
Languages : en
Pages : 897

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Book Description
Mass Spectrometry for Lipidomics All-in-one guide to successful lipidomic analysis, combining the latest advances and best practices from academia, industry, and clinical research Mass Spectrometry for Lipidomics presents a systematic overview of lipidomic analysis, covering established standards of lipid analysis, available technology, and key lipid classes, as well as applications in basic research, medicine, pharma, and the food industry. Through connecting recent technological advances with key application areas, this unique guide bridges the gap between academia and industry by translating the vast body of knowledge that has been gained in the past decade into much-needed practical advice for novices as well as routine users. Edited by the president and vice-president of the International Lipidomics Society with contributions from the top experts in lipid analysis, Mass Spectrometry for Lipidomics covers a wide range of key topics, including: Aspects of sample preparation, separation methods, different mass spectrometry modes, as well as identification and quantitation, including the use of bioinformatics tools for data analysis Identification, quantitation and profiling of lipids in different types of biological samples Analytical approaches for all major classes of biological lipids, from fatty acids to phospholipids to sterols Novel applications in biological research, clinical diagnostics, as well as food and crop science For analytical chemists, biochemists, clinical chemists, and analytical laboratories and hospitals, Mass Spectrometry for Lipidomics presents a comprehensive and authoritative overview of the subject, with unmatched expertise from practicing professionals actively involved in the latest research.

Towards Greater Selectivity and Peak Capacities in Multidimensional Separations of Complex Samples

Towards Greater Selectivity and Peak Capacities in Multidimensional Separations of Complex Samples PDF Author: Liana Sorina Roca
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Multidimensional Analytical Techniques in Environmental Research

Multidimensional Analytical Techniques in Environmental Research PDF Author: Regina Duarte
Publisher: Elsevier
ISBN: 0128188960
Category : Science
Languages : en
Pages : 314

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Book Description
Multidimensional Analytical Techniques in Environmental Research is a comprehensive resource on the many multidimensional analytical strategies to qualitatively and quantitatively assess and map the organic and inorganic pollutants in complex atmospheric, water and soil matrices. During the past two decades, the rapidly-evolving field of analytical instrumentation has produced sophisticated multidimensional tools capable of providing unique and in-depth knowledge on the chemical features of complex mixtures from these different environmental matrices. This book brings together the wealth of information in the current literature, assisting in the decision-making process by covering both the fundamentals and applications of these methodologies. Sections cover the wide variety of multidimensional analytical techniques, including multidimensional solution- and solid-state nuclear magnetic resonance (NMR) spectroscopy, ultrahigh-resolution mass spectrometry (MS), two-dimensional correlation spectroscopy, two-dimensional liquid and gas chromatography and capillary electrophoresis coupled to high-resolution detection techniques, and excitation-emission (EEM) fluorescence spectroscopy assisted by multiway data analysis tools, and the use of synchrotron-radiation-based techniques combined with other spectroscopic approaches to explore and map the speciation of elements. Identifies state-of-the-art multidimensional analytical methods for targeted and untargeted profiling of complex mixtures from different environmental matrices (soil, sediment, water, and air) Assesses the advantages and limitations of the most modern and sophisticated multidimensional analytical methods in environmental research Highlights the current challenges and potential future directions in the application of multidimensional analytical tools to advance the current understanding on the dynamics and fate of environmental pollutants in different environmental matrices

Analytical Characterization of Biotherapeutics

Analytical Characterization of Biotherapeutics PDF Author: Jennie R. Lill
Publisher: John Wiley & Sons
ISBN: 1119053102
Category : Science
Languages : en
Pages : 378

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Book Description
The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics research Analytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions. In addition, it frames critical questions warranting attention in the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules, and presents a number of tested solutions. The first single-volume guide of its kind, Analytical Characterization of Biotherapeutics brings together contributions from scientists at the leading edge of biotherapeutics research and manufacturing. Key topics covered in-depth include the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or other hybrid molecules, characterization of manufacturing host-cell contaminant proteins, analytical tools for biologics molecular assessment, and more. Each chapter is written by a recognized expert or experts in their field who discuss current and cutting edge approaches to fully characterizing biotherapeutic proteins and antigen reagents Covers the full range of characterization strategies for large molecule based therapeutics Provides an up-to-date account of the latest approaches used for large molecule characterization Chapters cover the background needed to understand the challenges at hand, solutions to characterize these large molecules, and a summary of emerging options for analytical characterization Analytical Characterization of Biotherapeutics is an up-to-date resource for analytical scientists, biologists, and mass spectrometrists involved in the analysis of biomolecules, as well as scientists employed in the pharmaceuticals and biotechnology industries. Graduate students in biology and analytical science, and their instructors will find it to be fascinating and instructive supplementary reading.

Protein Purification

Protein Purification PDF Author: Jan-Christer Janson
Publisher: John Wiley & Sons
ISBN: 1118002199
Category : Science
Languages : en
Pages : 542

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Book Description
The authoritative guide on protein purification—now completely updated and revised Since the Second Edition of Protein Purification was published in 1998, the sequencing of the human genome and other developments in bioscience have dramatically changed the landscape of protein research. This new edition addresses these developments, featuring a wealth of new topics and several chapters rewritten from scratch. Leading experts in the field cover all major biochemical separation methods for proteins in use today, providing professionals in biochemistry, organic chemistry, and analytical chemistry with quick access to the latest techniques. Entirely new or thoroughly revised content includes: High-resolution reversed-phase liquid chromatography Electrophoresis in gels Conventional isoelectric focusing in gel slabs and capillaries and immobilized pH gradients Affinity ligands from chemical and biological combinatorial libraries Membrane separations Refolding of inclusion body proteins from E. coli Purification of PEGylated proteins High throughput screening techniques in protein purification The history of protein chromatography

Foodomics

Foodomics PDF Author: Jorge Barros-Velázquez
Publisher: Royal Society of Chemistry
ISBN: 1839163011
Category : Science
Languages : en
Pages : 384

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Book Description
Presenting an up-to-date review of the state-of-the-art and main applications of omics technologies to current hot topics in food sciences, this book is divided into four convenient sections. The first section represents an introduction to the development of foodomics and will provide a general overview of DNA-based and protein-based methods. The second section is focused on the main applications of omics to food safety issues, such as chemical hazards, foodborne pathogens, phages, food authentication or GMO detection. The third section is focused on specific food groups and how omics have revolutionized the investigation of dairy and meat products, seafood, agricultural and fermented food products. Finally, the fourth section is devoted to the link between foodomics and health: hot topics such as nutrimetabolomics, food allergy or probiotics are reviewed here. The book brings together work from top international scientists to produce the most significant academic book for some years on omics and food for a broad audience. It presents unique features not covered so far by other books, such as a detailed description of different strategies and applications of omics techniques to many food sectors and provides a welcome addition to the cutting-edge literature in this area for researchers and professionals in food science and food chemistry.