Developing a Canine Model of Idiopathic Epilepsy PDF Download
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Author: Edward Earl Patterson
Publisher:
ISBN:
Category : Epilepsy
Languages : en
Pages : 298
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Book Description
Author: Edward Earl Patterson
Publisher:
ISBN:
Category : Epilepsy
Languages : en
Pages : 298
Get Book Here
Book Description
Author: Ramesh C. Gupta
Publisher: Springer
ISBN: 3030046249
Category : Science
Languages : en
Pages : 877
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Book Description
This unique work compiles the latest knowledge around veterinary nutraceuticals, commonly referred to as dietary supplements, from ingredients to final products in a single source. More than sixty chapters organized in seven sections collate all related aspects of nutraceutical research in animal health and disease, among them many novel topics: common nutraceutical ingredients (Section-I), prebiotics, probiotics, synbiotics, enzymes and antibacterial alternatives (Section-II), applications of nutraceuticals in prevention and treatment of various diseases such as arthritis, periodontitis, diabetes, cognitive dysfunctions, mastitis, wounds, immune disorders, and cancer (Section-III), utilization of nutraceuticals in specific animal species (Section-IV), safety and toxicity evaluation of nutraceuticals and functional foods (Section-V), recent trends in nutraceutical research and product development (Section-VI), as well as regulatory aspects for nutraceuticals (Section-VII). The future of nutraceuticals and functional foods in veterinary medicine seems bright, as novel nutraceuticals will emerge and new uses of old agents will be discovered. International contributors to this book cover a variety of specialties in veterinary medicine, pharmacology, pharmacognosy, toxicology, chemistry, medicinal chemistry, biochemistry, physiology, nutrition, drug development, regulatory frameworks, and the nutraceutical industry. This is a highly informative and carefully presented book, providing scientific insight for academia, veterinarians, governmental and regulatory agencies with an interest in animal nutrition, complementary veterinary medicine, nutraceutical product development and research.
Author: Jacqueline A. Hubbard
Publisher: Academic Press
ISBN: 0128026243
Category : Medical
Languages : en
Pages : 395
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Book Description
Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation
Author: Luisa de Risio
Publisher: CABI
ISBN: 1780641095
Category : Medical
Languages : en
Pages : 617
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Book Description
Epilepsy is one of the most familiar chronic neurological diseases and is a common yet challenging presentation in veterinary surgeries. This book covers seizure pathogenesis, classifications, diagnostic investigations, emergency treatments and longer term treatments, with a large section on pharmacological intervention. Filling a considerable gap in the veterinary literature, it includes tables and charts for quick reference during emergencies. Seizures can be very distressing to animals and owners, yet not all seizures are the result of epilepsy, a neurological condition. This book discusses how to distinguish between epileptic and non-neurological seizures, and provides case studies to illustrate different occurrences of epilepsy.
Author: Asla Pitkänen
Publisher: Academic Press
ISBN: 012804067X
Category : Medical
Languages : en
Pages : 1180
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Book Description
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Author: Sean Sanders
Publisher: John Wiley & Sons
ISBN: 1118689747
Category : Medical
Languages : en
Pages : 356
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Book Description
Seizures in Dogs and Cats offers a practical, complete resource for the veterinary management of seizures in dog and cat patients. The book is carefully designed for ease of use in the clinical setting, presenting clinically oriented information on the etiology, diagnosis, and management of seizures. Each chapter begins with key points, then presents greater detail, making the book equally useful for fast access during the exam and for further reference. The book begins with chapters on the history, biology, and classification of seizures, then covers diagnosis, medical and surgical treatment, emergencies, and complementary medicine. Unique chapters cover client communications and potential future directions of the field. Seizures in Dogs and Cats puts all the information needed to manage seizures in the veterinary clinic at your fingertips.
Author: Gonzalo Alarcón
Publisher: Cambridge University Press
ISBN: 0521691583
Category : Medical
Languages : en
Pages : 641
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Book Description
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
Author: Simon Platt
Publisher: BSAVA
ISBN: 9781905319343
Category : Medical
Languages : en
Pages : 552
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Book Description
This best selling manual has been fully revised and updated with the latest information. New chapters include neurological genetic disease testing and counselling; adjunctive therapies; and nutrition. This edition will also feature a DVD-ROM with video clips.
Author: Andrea Fischer
Publisher: Frontiers Media SA
ISBN: 2832520278
Category : Medical
Languages : en
Pages : 230
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Book Description
Author: José Miguel Vela
Publisher: John Wiley & Sons
ISBN: 3527333282
Category : Medical
Languages : en
Pages : 600
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Book Description
This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on the use of animals in the early part of the drug development process, including regulatory rules and limitations, as well as numerous examples from real-life drug development projects. After a general introduction to the topic, the expert contributors from research-driven pharmaceutical companies discuss the basic considerations of using animal models, including ethical issues. The main part of the book systematically surveys the most important disease areas for current drug development, from cardiovascular to endocrine disorders, and from infectious to neurological diseases. For each area, the availability of animal models for target validation, hit finding and lead profiling is reviewed, backed by numerous examples of both successes and failures among the use of animal models. The whole is rounded off with a discussion of perspectives and challenges. Key knowledge for drug researchers in industry as well as academia.
