Design Characteristics for Facilities which Process Hazardous Particulate

Design Characteristics for Facilities which Process Hazardous Particulate PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 13

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Book Description
Los Alamos National Laboratory is establishing a research and processing capability for beryllium. The unique properties of beryllium, including light weight, rigidity, thermal conductivity, heat capacity, and nuclear properties make it critical to a number of US defense and aerospace programs. Concomitant with the unique engineering properties are the health hazards associated with processing beryllium in a particulate form and the potential for worker inhalation of aerosolized beryllium. Beryllium has the lowest airborne standard for worker protection compared to all other nonradioactive metals by more than an order of magnitude. This paper describes the design characteristics of the new beryllium facility at Los Alamos as they relate to protection of the workforce. Design characteristics to be reviewed include; facility layout, support systems to minimize aerosol exposure and spread, and detailed review of the ventilation system design for general room air cleanliness and extraction of particulate at the source.

Design Characteristics for Facilities which Process Hazardous Particulate

Design Characteristics for Facilities which Process Hazardous Particulate PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 13

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Book Description
Los Alamos National Laboratory is establishing a research and processing capability for beryllium. The unique properties of beryllium, including light weight, rigidity, thermal conductivity, heat capacity, and nuclear properties make it critical to a number of US defense and aerospace programs. Concomitant with the unique engineering properties are the health hazards associated with processing beryllium in a particulate form and the potential for worker inhalation of aerosolized beryllium. Beryllium has the lowest airborne standard for worker protection compared to all other nonradioactive metals by more than an order of magnitude. This paper describes the design characteristics of the new beryllium facility at Los Alamos as they relate to protection of the workforce. Design characteristics to be reviewed include; facility layout, support systems to minimize aerosol exposure and spread, and detailed review of the ventilation system design for general room air cleanliness and extraction of particulate at the source.

Process Architecture in Biomanufacturing Facility Design

Process Architecture in Biomanufacturing Facility Design PDF Author: Jeffery Odum
Publisher: John Wiley & Sons
ISBN: 1118833651
Category : Science
Languages : en
Pages : 381

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Book Description
Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature—and it’s rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements. Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future. Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO—especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies Includes many diagrams that clarify the design approach Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.

Fundamentals of Environmental Chemistry, Third Edition

Fundamentals of Environmental Chemistry, Third Edition PDF Author: Stanley E. Manahan
Publisher: CRC Press
ISBN: 1420052691
Category : Science
Languages : en
Pages : 1266

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Book Description
Written by an expert, using the same approach that made the previous two editions so successful, Fundamentals of Environmental Chemistry, Third Edition expands the scope of book to include the strongly emerging areas broadly described as sustainability science and technology, including green chemistry and industrial ecology. The new edition includes: Increased emphasis on the applied aspects of environmental chemistry Hot topics such as global warming and biomass energy Integration of green chemistry and sustainability concepts throughout the text More and updated questions and answers, including some that require Internet research Lecturers Pack on CD-ROM with solutions manual, PowerPoint presentations, and chapter figures available upon qualifying course adoptions The book provides a basic course in chemical science, including the fundamentals of organic chemistry and biochemistry. The author uses real-life examples from environmetnal chemistry, green chemistry, and related areas while maintaining brevity and simplicity in his explanation of concepts. Building on this foundation, the book covers environmental chemistry, broadly defined to include sustainability aspects, green chemistry, industrial ecology, and related areas. These chapters are organized around the five environmental spheres, the hydrosphere, atmosphere, geosphere, biosphere, and the anthrosphere. The last two chapters discuss analytical chemistry and its relevance to environmental chemistry. Manahan’s clear, concise, and readable style makes the information accessible, regardless of the readers’ level of chemistry knowledge. He demystifies the material for those who need the basics of chemical science for their trade, profession, or study curriculum, as well as for readers who want to have an understanding of the fundamentals of sustainable chemistry in its crucial role in maintaining a livable planet.

Prudent Practices in the Laboratory

Prudent Practices in the Laboratory PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309211581
Category : Science
Languages : en
Pages : 360

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Book Description
Prudent Practices in the Laboratory-the book that has served for decades as the standard for chemical laboratory safety practice-now features updates and new topics. This revised edition has an expanded chapter on chemical management and delves into new areas, such as nanotechnology, laboratory security, and emergency planning. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices in the Laboratory provides guidance on planning procedures for the handling, storage, and disposal of chemicals. The book offers prudent practices designed to promote safety and includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices in the Laboratory will continue to serve as the leading source of chemical safety guidelines for people working with laboratory chemicals: research chemists, technicians, safety officers, educators, and students.

Good Design Practices for GMP Pharmaceutical Facilities

Good Design Practices for GMP Pharmaceutical Facilities PDF Author: Terry Jacobs
Publisher: CRC Press
ISBN: 1482258919
Category : Medical
Languages : en
Pages : 535

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Book Description
This revised publication serves as a handy and current reference for professionals engaged in planning, designing, building, validating and maintaining modern cGMP pharmaceutical manufacturing facilities in the U.S. and internationally. The new edition expands on facility planning, with a focus on the ever-growing need to modify existing legacy facilities, and on current trends in pharmaceutical manufacturing which include strategies for sustainability and LEED building ratings. All chapters have been re-examined with a fresh outlook on current good design practices.

Evaluating Genetic Testing for Susceptibility to Occupationally-induced Disease

Evaluating Genetic Testing for Susceptibility to Occupationally-induced Disease PDF Author: Geoffrey Peter Lomax
Publisher:
ISBN:
Category :
Languages : en
Pages : 312

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Book Description


Guidelines for Safe Handling of Powders and Bulk Solids

Guidelines for Safe Handling of Powders and Bulk Solids PDF Author: CCPS (Center for Chemical Process Safety)
Publisher: John Wiley & Sons
ISBN: 0470925051
Category : Technology & Engineering
Languages : en
Pages : 816

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Book Description
Powders and bulk solids, handled widely in the chemical, pharmaceutical, agriculture, smelting, and other industries present unique fire, explosion, and toxicity hazards. Indeed, substances which are practically inert in consolidated form may become quite hazardous when converted to powders and granules. The U.S. Chemical Safety and Hazard Investigation Board is currently investigating dust explosions that occured in 2003 at WestPharma, CTA Acoustics, and Hayes-Lemmerz, and is likely to recommend that companies that handle powders or whose operations produce dust pay more attention to understanding the hazards that may exist at their facility. This new CCPS guidelines book will discuss the types of hazards that can occur in a wide range of process equipment and with a wide range of substances, and will present measures to address these hazards.

Waste Incineration and Public Health

Waste Incineration and Public Health PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030906371X
Category : Science
Languages : en
Pages : 336

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Book Description
Incineration has been used widely for waste disposal, including household, hazardous, and medical wasteâ€"but there is increasing public concern over the benefits of combusting the waste versus the health risk from pollutants emitted during combustion. Waste Incineration and Public Health informs the emerging debate with the most up-to-date information available on incineration, pollution, and human healthâ€"along with expert conclusions and recommendations for further research and improvement of such areas as risk communication. The committee provides details on: Processes involved in incineration and how contaminants are released. Environmental dynamics of contaminants and routes of human exposure. Tools and approaches for assessing possible human health effects. Scientific concerns pertinent to future regulatory actions. The book also examines some of the social, psychological, and economic factors that affect the communities where incineration takes place and addresses the problem of uncertainty and variation in predicting the health effects of incineration processes.

Facility Fire Brigade: Principles and Practice includes Navigate Advantage Access

Facility Fire Brigade: Principles and Practice includes Navigate Advantage Access PDF Author: International Association of Fire Chiefs
Publisher: Jones & Bartlett Learning
ISBN: 1284202852
Category : Technology & Engineering
Languages : en
Pages : 856

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Book Description
A Complete Facility Fire Brigade Training Solution The National Fire Protection Association (NFPA) and the International Association of Fire Chiefs (IAFC) are pleased to bring you the Second Edition of Facility Fire Brigade: Principles and Practice, a modern integrated teaching and learning system for four levels of a Facility Fire Brigade. These four levels are: Incipient Facility Fire Brigade Member Advanced Exterior Facility Fire Brigade Member Interior Structural Facility Fire Brigade Member Facility Fire Brigade Leader. Today's facility fire brigade members protect all types of facilities. As they answer these calls, it is imperative that no gaps in knowledge compromise their effectiveness or their safety in protecting who they serve. Facility fire brigade members need up-to-date, comprehensive training materials to thoroughly prepare for any situation that may arise. Current Content This text addresses the 2018 Edition of the NFPA 1081, Standard for Facility Fire Brigade Member Professional Qualifications. It also provides essential guidance for compliance with OSHA Regulations 29 CFR § 1910.156, as well as NFPA 600, Standard on Facility Fire Brigades. Dynamic Features The features found in the text will help your students take that extra step toward becoming outstanding fire brigade members. They include: Detailed Case Studies Expanded Skill Drills Advice and encouragement from veteran facility brigade leaders

Nuclear Science Abstracts

Nuclear Science Abstracts PDF Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 1220

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Book Description