Data Driven Science for Clinically Actionable Knowledge in Diseases

Data Driven Science for Clinically Actionable Knowledge in Diseases PDF Author: Daniel R. Catchpoole
Publisher: CRC Press
ISBN: 1003801684
Category : Medical
Languages : en
Pages : 221

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Book Description
Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.

Data Driven Science for Clinically Actionable Knowledge in Diseases

Data Driven Science for Clinically Actionable Knowledge in Diseases PDF Author: Daniel R. Catchpoole
Publisher: CRC Press
ISBN: 1003801684
Category : Medical
Languages : en
Pages : 221

Get Book Here

Book Description
Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.

Data Driven Science for Clinically Actionable Knowledge in Diseases

Data Driven Science for Clinically Actionable Knowledge in Diseases PDF Author: Daniel R. Catchpoole
Publisher:
ISBN: 9781003292357
Category : Diseases
Languages : en
Pages : 0

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Book Description
Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.

Data Driven Science for Clinically Actionable Knowledge in Diseases

Data Driven Science for Clinically Actionable Knowledge in Diseases PDF Author: Daniel Catchpoole
Publisher: CRC Press
ISBN: 1003800289
Category : Medical
Languages : en
Pages : 255

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Book Description
Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.

Handbook of Research on AI Methods and Applications in Computer Engineering

Handbook of Research on AI Methods and Applications in Computer Engineering PDF Author: Kaddoura, Sanaa
Publisher: IGI Global
ISBN: 1668469391
Category : Computers
Languages : en
Pages : 659

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Book Description
The development of artificial intelligence (AI) involves the creation of computer systems that can do activities that would ordinarily require human intelligence, such as visual perception, speech recognition, decision making, and language translation. Through increasingly complex programming approaches, it has been transforming and advancing the discipline of computer science. The Handbook of Research on AI Methods and Applications in Computer Engineering illuminates how today’s computer engineers and scientists can use AI in real-world applications. It focuses on a few current and emergent AI applications, allowing a more in-depth discussion of each topic. Covering topics such as biomedical research applications, navigation systems, and search engines, this premier reference source is an excellent resource for computer scientists, computer engineers, IT managers, students and educators of higher education, librarians, researchers, and academicians.

Leveraging Data Science for Global Health

Leveraging Data Science for Global Health PDF Author: Leo Anthony Celi
Publisher: Springer Nature
ISBN: 3030479943
Category : Medical
Languages : en
Pages : 471

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Book Description
This open access book explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources. Developing countries are uniquely prone to large-scale emerging infectious disease outbreaks due to disruption of ecosystems, civil unrest, and poor healthcare infrastructure – and without comprehensive surveillance, delays in outbreak identification, resource deployment, and case management can be catastrophic. In combination with context-informed analytics, students will learn how non-traditional digital disease data sources – including news media, social media, Google Trends, and Google Street View – can fill critical knowledge gaps and help inform on-the-ground decision-making when formal surveillance systems are insufficient.

Data Science and Medical Informatics in Healthcare Technologies

Data Science and Medical Informatics in Healthcare Technologies PDF Author: Nguyen Thi Dieu Linh
Publisher: Springer Nature
ISBN: 9811630291
Category : Technology & Engineering
Languages : en
Pages : 91

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Book Description
This book highlights a timely and accurate insight at the endeavour of the bioinformatics and genomics clinicians from industry and academia to address the societal needs. The contents of the book unearth the lacuna between the medication and treatment in the current preventive medicinal and pharmaceutical system. It contains chapters prepared by experts in life sciences along with data scientists for examining the circumstances of health care system for the next decade. It also highlights the automated processes for analyzing data in clinical trial research, specifically for drug development. Additionally, the data science solutions provided in this book help pharmaceutical companies to improve on what had historically been manual, costly and laborious process for cross-referencing research in clinical trials on drug development, while laying the groundwork for use with a full range of other drugs for the conditions ranging from tuberculosis, to diabetes, to heart attacks and many others.

Discovering Data-Driven Actionable Intelligence for Clinical Decision Support

Discovering Data-Driven Actionable Intelligence for Clinical Decision Support PDF Author: Ahmed Mohamed Alaa Ibrahim
Publisher:
ISBN:
Category :
Languages : en
Pages : 215

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Book Description
The rapid digitization of healthcare has led to a proliferation of clinical data, manifesting through electronic health records, biorepositories, and disease registries. This dissertation addresses the question of how machine learning (ML) techniques can capitalize on these data resources to assist clinicians in predicting, preventing and treating illness. To this end, we develop a set of MLbased, data-driven models of patient outcomes that we envision to be embedded within systems of decision support deployed at different stages of patient care. We focus on two broad setups for analyzing clinical data: (1) the cross-sectional setup wherein data is collected by observing many patients at a particular point of time, and (2) the longitudinal setup in which repeated observations of the same patient are collected over time. In both setups, we develop models that are: (a) capable of answering counter-factual questions, i.e., can predict outcomes under alternative treatment scenarios, (b) interpretable in the sense that clinicians can understand how the model predictions for individual patients are issued, and (c) automated in the sense that they adaptively tune their modeling choices for the dataset at hand, with little or no need for expert intervention. Models satisfying these three requirements would enable the realization of actionable, transparent and automated decision support systems that operate symbiotically within existing clinical workflows. Our technical contributions are multi-faceted. In the cross-sectional data setup, we develop ML models that fulfill the aforementioned requirements (a)-(c) as follows. We start by developing a comprehensive theoretical framework for causal inference, whereby we quantify the limits to how well ML models can recover the causal effects of counter-factual treatment decisions on individual patients using observational (retrospective) data, and we build ML models -- based on Gaussian processes -- that achieve these limits. Next, we develop a novel symbolic meta-modeling approach for interpreting the predictions of any ML-based prognostic model by converting the "black-box" model into an understandable symbolic equation that relates patients' features to their predicted outcomes. Finally, we develop a model selection approach based on Bayesian optimization that enables the automation of predictive and causal modeling. In the longitudinal data setup, we develop a novel deep probabilistic model for sequential clinical data that satisfies requirements (a)- (c) by capitalizing on the strengths of both state-space models and deep recurrent neural networks. To demonstrate the utility of our models, we evaluate their performance on various real-world datasets for cohorts of breast cancer, cardiovascular disease and cystic fibrosis patients. We show that, compared to existing clinical scorers, our ML-based models can improve the accuracy of predicting individual-level prognoses, guide treatment decisions for individual patients, and provide insights into underlying disease mechanisms.

Precision Medicine and Artificial Intelligence

Precision Medicine and Artificial Intelligence PDF Author: Michael Mahler
Publisher: Academic Press
ISBN: 032385432X
Category : Science
Languages : en
Pages : 302

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Book Description
Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. - Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions - Provides background, milestone and examples of precision medicine - Outlines the paradigm shift towards precision medicine driven by value-based systems - Discusses future applications of precision medicine research using AI - Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine

Data Science in Critical Care, an Issue of Critical Care Clinics: Volume 39-4

Data Science in Critical Care, an Issue of Critical Care Clinics: Volume 39-4 PDF Author: Rishikesan Kamaleswaran
Publisher: Clinics: Internal Medicine
ISBN: 9780443181931
Category : Medical
Languages : en
Pages : 0

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Book Description
In this issue of Critical Care Clinics, guest editors Drs. Rishikesan Kamaleswaran and Andre L. Holder bring their considerable expertise to the topic of Data Science in Critical Care. Data science, the field of study dedicated to the principled extraction of knowledge from complex data, is particularly relevant in the critical care setting. In this issue, top experts in the field cover key topics such as refining our understanding and classification of critical illness using biomarker-based phenotyping; predictive modeling using AI/ML on EHR data; classification and prediction using waveform-based data; creating trustworthy and fair AI systems; and more. Contains 15 relevant, practice-oriented topics including AI and the imaging revolution; designing "living, breathing" clinical trials: lessons learned from the COVID-19 pandemic; the patient or the population: knowing the limitations of our data to make smart clinical decisions; weighing the cost vs. benefit of AI in healthcare; and more. Provides in-depth clinical reviews on data science in critical care, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Artificial Intelligence in Healthcare

Artificial Intelligence in Healthcare PDF Author: Adam Bohr
Publisher: Academic Press
ISBN: 0128184396
Category : Computers
Languages : en
Pages : 385

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Book Description
Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. - Highlights different data techniques in healthcare data analysis, including machine learning and data mining - Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks - Includes applications and case studies across all areas of AI in healthcare data