Author: Kimoon Kim
Publisher: Royal Society of Chemistry
ISBN: 1788015002
Category : Science
Languages : en
Pages : 572
Book Description
This book provides a complete overview of cucurbituril chemistry, covering fundamental aspects including history, synthesis and host-guest chemistry.
Cucurbiturils and Related Macrocycles
Author: Kimoon Kim
Publisher: Royal Society of Chemistry
ISBN: 1788015002
Category : Science
Languages : en
Pages : 572
Book Description
This book provides a complete overview of cucurbituril chemistry, covering fundamental aspects including history, synthesis and host-guest chemistry.
Publisher: Royal Society of Chemistry
ISBN: 1788015002
Category : Science
Languages : en
Pages : 572
Book Description
This book provides a complete overview of cucurbituril chemistry, covering fundamental aspects including history, synthesis and host-guest chemistry.
Cucurbiturils and Related Macrocycles
Author: Kimoon Kim
Publisher: Royal Society of Chemistry
ISBN: 1788019172
Category : Science
Languages : en
Pages : 572
Book Description
Cucurbiturils (CBs) are a young family of molecular containers, able to form stable complexes with various guests, including drug molecules, amino acids and peptides, saccharides, dyes, hydrocarbons, perfluorinated hydrocarbons, and proteins. Since the discovery of the first CB, the field has seen tremendous growth with respect to the synthesis of new homologues and derivatives, the discovery of record binding affinities of guest molecules in their hydrophobic cavity, and associated applications ranging from sensing to drug delivery. Cucurbiturils and Related Macrocycles provides a complete overview of CB chemistry, covering the fundamental aspects including its history, synthesis, host–guest chemistry and the thermodynamic basis thereof. The book will tackle specialist topics such as redox chemistry of CB complexes and CBs in the gas phase, and will address the recent trends of the application of CBs in other fields including biology and materials. Edited by a pioneer of cucurbituril chemistry, and with contributions from global experts, this title will appeal to students and researchers working in supramolecular chemistry, materials chemistry, nanotechnology, organic chemistry, biochemistry and chemical biology.
Publisher: Royal Society of Chemistry
ISBN: 1788019172
Category : Science
Languages : en
Pages : 572
Book Description
Cucurbiturils (CBs) are a young family of molecular containers, able to form stable complexes with various guests, including drug molecules, amino acids and peptides, saccharides, dyes, hydrocarbons, perfluorinated hydrocarbons, and proteins. Since the discovery of the first CB, the field has seen tremendous growth with respect to the synthesis of new homologues and derivatives, the discovery of record binding affinities of guest molecules in their hydrophobic cavity, and associated applications ranging from sensing to drug delivery. Cucurbiturils and Related Macrocycles provides a complete overview of CB chemistry, covering the fundamental aspects including its history, synthesis, host–guest chemistry and the thermodynamic basis thereof. The book will tackle specialist topics such as redox chemistry of CB complexes and CBs in the gas phase, and will address the recent trends of the application of CBs in other fields including biology and materials. Edited by a pioneer of cucurbituril chemistry, and with contributions from global experts, this title will appeal to students and researchers working in supramolecular chemistry, materials chemistry, nanotechnology, organic chemistry, biochemistry and chemical biology.
Dendrimer Chemistry
Author: Michael Malkoch
Publisher: Royal Society of Chemistry
ISBN: 178801944X
Category : Science
Languages : en
Pages : 327
Book Description
The unique structures and properties of dendrimers make them attractive for many applications, from drug delivery and antimicrobial agents to catalysis and as functional materials. Dendrimer Chemistry provides an overview of the latest advances in the synthesis of dendrimers and other complex dendritic architectures. The book focuses on established building block families for generating dendritic macromolecules, capitalizing on the evolution in the synthesis of dendrimers and other complex dendritic architectures. Systems covered range from dendritic polyesters and naturally occurring monomers to novel dendritic families. Each chapter starts with an introduction to the dendrimer family and its important features followed by information on the building blocks used to generate the dendrimers, their synthetic strategies and the resulting architectures. Chapters also cover the characterization and structural analysis, commercial availability and cutting-edge applications. Including forewords from leaders in the field, this will be a useful reference for postgraduate students and researchers in organic chemistry, polymer chemistry, materials science and macromolecular chemistry.
Publisher: Royal Society of Chemistry
ISBN: 178801944X
Category : Science
Languages : en
Pages : 327
Book Description
The unique structures and properties of dendrimers make them attractive for many applications, from drug delivery and antimicrobial agents to catalysis and as functional materials. Dendrimer Chemistry provides an overview of the latest advances in the synthesis of dendrimers and other complex dendritic architectures. The book focuses on established building block families for generating dendritic macromolecules, capitalizing on the evolution in the synthesis of dendrimers and other complex dendritic architectures. Systems covered range from dendritic polyesters and naturally occurring monomers to novel dendritic families. Each chapter starts with an introduction to the dendrimer family and its important features followed by information on the building blocks used to generate the dendrimers, their synthetic strategies and the resulting architectures. Chapters also cover the characterization and structural analysis, commercial availability and cutting-edge applications. Including forewords from leaders in the field, this will be a useful reference for postgraduate students and researchers in organic chemistry, polymer chemistry, materials science and macromolecular chemistry.
Reactivity in Confined Spaces
Author: Gareth O. Lloyd
Publisher: Royal Society of Chemistry
ISBN: 1788017765
Category : Science
Languages : en
Pages : 491
Book Description
This title combines classical host: guest chemistry with catalysis, reactivity and modern supramolecular chemistry
Publisher: Royal Society of Chemistry
ISBN: 1788017765
Category : Science
Languages : en
Pages : 491
Book Description
This title combines classical host: guest chemistry with catalysis, reactivity and modern supramolecular chemistry
Supramolecular Chemistry in Biomedical Imaging
Author: Stephen Faulkner
Publisher: Royal Society of Chemistry
ISBN: 183916137X
Category : Technology & Engineering
Languages : en
Pages : 310
Book Description
There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host–guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique. With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them. This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.
Publisher: Royal Society of Chemistry
ISBN: 183916137X
Category : Technology & Engineering
Languages : en
Pages : 310
Book Description
There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host–guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique. With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them. This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.
Supramolecular Protein Chemistry
Author: Peter B. Crowley
Publisher: Royal Society of Chemistry
ISBN: 1788017544
Category : Science
Languages : en
Pages : 329
Book Description
Assembly, Architecture and Application
Publisher: Royal Society of Chemistry
ISBN: 1788017544
Category : Science
Languages : en
Pages : 329
Book Description
Assembly, Architecture and Application
Porphyrin-based Supramolecular Architectures
Author: Shengqian Ma
Publisher: Royal Society of Chemistry
ISBN: 1839164948
Category : Science
Languages : en
Pages : 384
Book Description
Porphyrin-based Supramolecular Architectures focuses on the most recent developments in the field, emphasizing the cutting-edge research in a diverse range of applications. Designed for readers considering the unprecedented prosperity of porous materials research, chapters will cover both strategies for structure design (such as MOFs and COFs) as well as emerging applications including CO2 fixation, catalysis and photodynamic therapy. With contributions from global experts, this title will be of interest to graduate students and researchers in supramolecular chemistry, organic chemistry, inorganic chemistry, physical chemistry, organometallic chemistry, solid-state chemistry, catalysis and (porous) materials science.
Publisher: Royal Society of Chemistry
ISBN: 1839164948
Category : Science
Languages : en
Pages : 384
Book Description
Porphyrin-based Supramolecular Architectures focuses on the most recent developments in the field, emphasizing the cutting-edge research in a diverse range of applications. Designed for readers considering the unprecedented prosperity of porous materials research, chapters will cover both strategies for structure design (such as MOFs and COFs) as well as emerging applications including CO2 fixation, catalysis and photodynamic therapy. With contributions from global experts, this title will be of interest to graduate students and researchers in supramolecular chemistry, organic chemistry, inorganic chemistry, physical chemistry, organometallic chemistry, solid-state chemistry, catalysis and (porous) materials science.
Macrocycles
Author: Frank Davis
Publisher: John Wiley & Sons
ISBN: 1119990297
Category : Technology & Engineering
Languages : en
Pages : 1069
Book Description
Macrocyclic molecules contain rings made up of seven or more atoms. They are interesting because they provide building blocks for synthesizing precise two or three dimensional structures – an important goal in nanotechnology. For example, they can be used to develop nanosized reaction vessels, cages, switches and shuttles, and have potential as components in molecular computers. They also have applications as catalysts and sensors. Macrocycles: Construction, Chemistry and Nanotechnology Applications is an essential introduction this important class of molecules and describes how to synthesise them, their chemistry, how they can be used as nanotechnology building blocks, and their applications. A wide range of structures synthesised over the past few decades are covered, from the simpler cyclophanes and multi-ring aromatic structures to vases, bowls, cages and more complex multi-ring systems and 3D architectures such as “pumpkins”, interlocking chains and knots. Topics covered include: principles of macrocycle synthesis simple ring compounds multi-ring aromatic structures porphyrins and phthalocanines cyclophanes crown ethers, cryptands and spherands calixarenes, resorcinarenes, cavitands, carcerands, and heterocalixarenes cyclodextrins cucurbiturils cyclotriveratylenes rotaxanes catenanes complex 3D architectures, including trefoils and knots Macrocycles: Construction, Chemistry and Nanotechnology Applications distills the essence of this important topic for undergraduate and postgraduate students, and for researchers in other fields interested in getting a general insight into this increasingly important class of molecules.
Publisher: John Wiley & Sons
ISBN: 1119990297
Category : Technology & Engineering
Languages : en
Pages : 1069
Book Description
Macrocyclic molecules contain rings made up of seven or more atoms. They are interesting because they provide building blocks for synthesizing precise two or three dimensional structures – an important goal in nanotechnology. For example, they can be used to develop nanosized reaction vessels, cages, switches and shuttles, and have potential as components in molecular computers. They also have applications as catalysts and sensors. Macrocycles: Construction, Chemistry and Nanotechnology Applications is an essential introduction this important class of molecules and describes how to synthesise them, their chemistry, how they can be used as nanotechnology building blocks, and their applications. A wide range of structures synthesised over the past few decades are covered, from the simpler cyclophanes and multi-ring aromatic structures to vases, bowls, cages and more complex multi-ring systems and 3D architectures such as “pumpkins”, interlocking chains and knots. Topics covered include: principles of macrocycle synthesis simple ring compounds multi-ring aromatic structures porphyrins and phthalocanines cyclophanes crown ethers, cryptands and spherands calixarenes, resorcinarenes, cavitands, carcerands, and heterocalixarenes cyclodextrins cucurbiturils cyclotriveratylenes rotaxanes catenanes complex 3D architectures, including trefoils and knots Macrocycles: Construction, Chemistry and Nanotechnology Applications distills the essence of this important topic for undergraduate and postgraduate students, and for researchers in other fields interested in getting a general insight into this increasingly important class of molecules.
Cucurbiturils: Chemistry, Supramolecular Chemistry And Applications
Author: Kimoon Kim
Publisher: World Scientific
ISBN: 1848164092
Category : Science
Languages : en
Pages : 262
Book Description
This book chronicles the history and development of cucurbiturils. It provides a general introduction and a field-wide overview of the synthesis, properties and applications of cucurbiturils.Beginning with a chronicled history in the development of the once little-known peculiarity to the forefront of supramolecular chemistry, followed by an in depth look at the preparation, properties and host-guest chemistry, the title showcases the uses of cucurbiturils in chemistry, materials science and biology.An essential resource for both new and experienced researchers, as it provides an overview of the diverse applications, new methodologies and research, as well as challenges in the field.
Publisher: World Scientific
ISBN: 1848164092
Category : Science
Languages : en
Pages : 262
Book Description
This book chronicles the history and development of cucurbiturils. It provides a general introduction and a field-wide overview of the synthesis, properties and applications of cucurbiturils.Beginning with a chronicled history in the development of the once little-known peculiarity to the forefront of supramolecular chemistry, followed by an in depth look at the preparation, properties and host-guest chemistry, the title showcases the uses of cucurbiturils in chemistry, materials science and biology.An essential resource for both new and experienced researchers, as it provides an overview of the diverse applications, new methodologies and research, as well as challenges in the field.
Advances in Prodrugs
Author: Claudiu Trandafir Supuran
Publisher: Elsevier
ISBN: 0443156344
Category : Science
Languages : en
Pages : 380
Book Description
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases. - Highlights chemistry and pharmacology-related aspects, offering a versatile tool for readers involved in prodrug development and study - Discusses in-depth treatment of several activation mechanisms and applications for disease treatments - Covers a range of topics from basic contents, design, and mechanisms of actions to current applications in drugs
Publisher: Elsevier
ISBN: 0443156344
Category : Science
Languages : en
Pages : 380
Book Description
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases. - Highlights chemistry and pharmacology-related aspects, offering a versatile tool for readers involved in prodrug development and study - Discusses in-depth treatment of several activation mechanisms and applications for disease treatments - Covers a range of topics from basic contents, design, and mechanisms of actions to current applications in drugs