Author: Teruo Nishida
Publisher: Kugler Publications
ISBN: 9789062991570
Category : Medical
Languages : en
Pages : 160
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Book Description
PrefaceThe Santen International Symposium "Corneal Healing Responses to Injuries and Refractive Surgeries", was held to bring together those working in the field of corneal disorders and refractive surgeries to provide them with a forum in which the latest developments could be presented and discussed. Over the last decade, the crystal clear and transparent corneas have been challenged by various types of surgical insult to correct refractive errors. These Proceedings provide a comprehensive coverage of the material covered in this Symposium, allowing the reader to remain up-to-date on the lat
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Yan Wang
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0
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Book Description
Corneal biomechanics have been concerned recently since it is not only found to play an important role in the wound healing process after corneal refractive surgeries, but also essential to improve the predictability and safety of refractive procedures. Corneal biomechanics and wound healing responses are linked in time and space and may also cause complications of keratectasia, haze formation, and regression. This review focuses on wound healing and biomechanics of the corneal refractive procedures. Identifying corneal wound healing from the biomechanical point of view is mandatory to improve the outcomes and reduce the complications.
Author: Jorge L. Alió
Publisher: Springer
ISBN: 3030013049
Category : Medical
Languages : en
Pages : 510
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Book Description
This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy. Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.
Author: New Orleans Academy of Ophthalmology. Session
Publisher: Kugler Publications
ISBN: 9789062991402
Category : Medical
Languages : en
Pages : 326
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Book Description
Preface From Friday morning, February 21, 1997, through Sunday, February 23, at noon, members and guests of the New Orleans Academy of Ophthalmology heard presentations and discussions of the latest techniques and trends in the study of corneal diseases and surgery, including refractive surgery. This was the subject of the. Forty- Sixth Annual Symposium of the Academy. The speakers comprised a group of eight clinician-surgeons with a wealth of experience and a well-respected talent for innovation in their areas of expertise. From trends in bacterial keratitis to ocular surface disease and healing to the latest opinions on anterior segment reconstruction and refractive surgery, the topics covered were diverse and timely. Especially interesting were the discussions generated by the panelists' presentations and by the question and answer sessions. The demands placed on the speakers at the Annual Meeting of the New Orleans Academy of Ophthalmology are large and multiple, and probably greater than for most other educational conferences. Each speaker commits to preparing several lectures and usually a panel discussion for presentation, and all speakers are asked to participate in the panel discussions and question and answer periods. The topics are chosen by the program committee, and we sometimes ask speakers to present a subject that is not in their area of research or primary interest. This usually means researching and preparing a completely new lecture. And last, but not least, all speakers commit to preparing chapters and completing panel discussions for this book. And these duties are added to already busy practice and speaking schedules; in fact, the speakers are selected because they have new ideas and useful things to say that everyone wishes to hear. Not all invited speakers are up to the task, but this year we were fortunate that all of our first choices accepted the challenge. Because of the rapidity of change in both refractive surgery and anterior segment treatment, we have attempted to provide the transactions as rapidly as possible. This urgency has again added more demands on the time and energy of the speakers. And this group of authors has responded admirably to our requests. Because of their efforts the reader can use this publication as an update and as a gauge to his/her present practice guidelines. I wish to thank all eight speaker/authors for their efforts on behalf of the New Orleans Academy of Ophthalmology and the readers of this publication. The information presented here was put on paper by the authors, but we readers are the ones who benefit. In addition, they have added to a forty-year tradition of publications by the New Orleans Academy of Ophthalmology. I hope that readers consider this book as timely and as useful as previous issues of the Transactions. I also wish to thank Monica L. Monica, MD, President of the NOAO, and the Executive Committee for supporting the program and this publication. As always, a considerable amount of time and effort came from Emily Busby, executive secretary of the NOAO, and my thanks go to her, as well. Lastly, Marguerite McDonald, MD, deserves much credit in the organization of the meeting and the program. Her knowledge and experience were truly indispensable. Daniel A. Long, MD
Author: C.J. Roberts
Publisher: Kugler Publications
ISBN: 9062998763
Category : Medical
Languages : en
Pages : 328
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Book Description
While lecturing in recent months at a number of prominent institutions, I asked some of the residents and fellows whether and how they might benefit from a book on corneal biomechanics. The typical response was the look of a deer caught in the headlights as they tried to intuit the “appropriate” answer, but had little understanding or insight as to why this would be an important and useful knowledge base for them now, or in the future. I then posed the question differently. “Would a book that explained corneal biomechanical principles and testing devices and their application in detecting eyes at risk for developing keratoconus and post-LASIK ectasia, understanding the biomechanical impact of specific types of keratorefractive surgery and riboflavin UV-A corneal collagen cross-linking, and the impact of corneal biomechanics on the fidelity of intraocular pressure measurement and risk for glaucoma progression be of interest?” Framed in this context, the answer I got was a resounding, “Yes!” Therein lies a fundamental disconnect that highlights both the opportunity and need to educate all ophthalmologists about this nascent field. This comprehensive book is strengthened by the breadth of contributions from leading experts around the world and provides an important resource for ophthalmologists at all levels of training and experience. It gives a panoramic snapshot of our understanding of corneal biomechanics today, bridging the gap between theoretical principles, testing devices that are commercially available and in development as well as current and potential future clinical applications. While there has been a long-held appreciation that all types of keratorefractive surgery have an impact and interdependence on corneal biomechanics and wound healing, the initial finite element analyses that were applied to understand radial keratotomy were limited by incorrect assumptions that the cornea was a linear, elastic, homogenous, isotropic material.1 With the advent of excimer laser vision correction, critical observations indicated that Munnerlyn’s theoretic ablation profiles did not account for either lower or higher order (e.g. spherical aberration) refractive outcomes,2 suggesting that there were important components missing from the equation—e.g., corneal biomechanics and wound healing. In a seminal editorial, Roberts3 pointed out that the cornea is not a piece of plastic, but rather a material with viscoelastic qualities. Since that time, much has been learned about spatial and depth- related patterns of collagen orientation and interweaving, as well as the biomechanical response to different keratorefractive surgeries that sever tension-bearing lamellae, as the cornea responds to and redistributes stress induced by IOP, hydration, eye rubbing, blinking and extraocular muscle forces.3-6 The first reports of post-LASIK ectasia7 highlighted the need to identify a biomechanical signature of early keratoconus as well as corneas at high risk of developing ectasia irrespective of their current topography or tomography. The introduction of two instruments into clinical use—the Ocular Response Analyzer (ORA) and the Corneal Visualization Scheimpflug Technology (Corvis ST)—that allow measurement of various biomechanical metrics further catapulted the field. The availability of these instruments in routine clinical settings allowed the systematic study of the effect of age, collagen disorders, collagen cross-linking, corneal rings, flaps of various depths, contour, sidecut angulation, pockets, and flockets, just to name of few. Future application of biomechanics to the sclera may improve our understanding of the development and prevention of myopia, as well as scleral surgeries and treatments under development for presbyopia. It was appreciated by Goldmann and Schmidt that corneal thickness and curvature would influence the measurement of applanation tonometry. The recent ability to measure some corneal biomechanical metrics have led to IOP measurement that may be more immune both to their influence and the impact of central corneal thickness (CCT). Certain chapters in this book explain how a thin cornea could be stiffer than a thick one and that stiffness is also impacted by IOP, thereby precluding simplistic attempts to adjust IOP measurements using nomograms based upon CCT alone. Also highlighted is how corneal hysteresis, the ability of the cornea to absorb and dissipate energy during the bidirectional applanation response to a linear Gaussian air puff, appears to be an independent risk factor for glaucoma progression and rate of progression.9,10 This comprehensive book starts out with a section devoted to outlining basic biomechanical principles and theories, teaching us the language of what Dupps11 has referred to as “mechanospeak”, thus providing a context and common vocabulary to better comprehend the following chapters. By first defining basic concepts such as stress-strain relationships and creep, this theoretical basis is later applied to explain the pathogenesis of corneal diseases, e.g., explaining how a focal abnormality in corneal biomechanical properties precipitates a cycle of decompensation and localized thinning and steepening, clinically expressed as ectasia progression. These early chapters further detail biomechanical differences between in-vivo and ex-vivo testing, between human and animal corneas and sclera, and between methods of testing. The second section provides a thorough description of two FDA-approved devices to measure corneal biomechanics in the clinic (i.e., the ORA and the Corvis ST), as well as an overview of potential future technologies, including OCT with air puff stimulus, ocular pulse elastography, and Brilloiun microscopy. The third and final section of the book is a thorough treatise on how to interpret the metrics derived from the waveform provided by available clinical devices; their adjunct use in ectasia risk screening; the comparative biomechanical impact of various keratorefractive surgeries and corneal procedures such as PRK, LASIK, SMILE, and corneal collagen cross-linking; the impact of corneal biomechanics on IOP measurement; and potential biomechanical markers of enhanced susceptibility to glaucoma progression. This compendium of our current knowledge of corneal biomechanics, its measurement and application, provides a strong foundation to more fully understand advances in keratorefractive and corneal surgery, diseases, and treatments, all of which are interdependent on and influence inherent corneal biomechanical properties and behavior. Both the robust aspects and limitations of our current understanding are presented, including the challenge of creating accurate and predictive finite element models that incorporate the impact of IOP, corneal thickness, geometry, and scleral properties on corneal biomechanics. This book provides a key allowing clinical ophthalmologists and researchers to grasp the basics and nuances of this exciting field and to shape it as it evolves in the future.
Author: Ashim K Mitra
Publisher: Elsevier
ISBN: 190881831X
Category : Science
Languages : en
Pages : 276
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Book Description
Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. - Highly focused on ocular transporters - Most up-to-date research compilation - Detailed description of role of transporters and receptors in ocular drug discovery and delivery
Author: Richard E. Selser
Publisher: Kugler Publications
ISBN: 9789062991068
Category : Cornea
Languages : en
Pages : 214
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Book Description
Author: Frederick S. Brightbill
Publisher: Elsevier Health Sciences
ISBN: 0323048358
Category : Medical
Languages : en
Pages : 970
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Book Description
Part. 1 Introduction to corneal function and surgery -- Part. 2 Testing and measuring corneal function -- Part. 3 Ocular surface surgery and reconstruction -- Part. 4 Techniques in corneal transplantation -- Part. 5 Special situations in corneal surgery -- Part. 6 Surgical correction of refractive errors.
Author: Richard Elander
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 714
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Book Description
Introducing the first comprehensive textbook covering all aspects of refractive surgery. Provides the reader with a broad, in-depth description of the principles, theories, methods, instrumentation, and economics involved with incisional, lamellar, and laser surgery correction of refractive errors. Includes contributions from international authorities, and provides comprehensive coverage of currently available instrumentations.
