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Author:
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ISBN:
Category : Alcoholism
Languages : en
Pages : 34
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Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 34
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Book Description
Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 28
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Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 54
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Author: Rick Csiernik
Publisher: Canadian Scholars
ISBN: 1773383426
Category : Social Science
Languages : en
Pages : 516
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Book Description
Responding to the Oppression of Addiction brings together the voices of over 40 academics and social work practitioners from across Canada to provide a diverse and multidimensional perspective to the study of addiction. This thoroughly updated edition features eight new chapters and streamlines the content of the previous editions, with chapters condensed and combined to create a more accessible text. The fourth edition features new content on themes such as residential schools, prevention initiatives, special needs of different populations, policy perspectives framed within an anti-oppression standpoint, cognitive behavioral therapy, and the emerging topic of problem gambling. Returning chapters have been updated, with contributors providing more in-depth examinations of trauma-informed approaches. The entire volume has a strengthened anti-oppressive framework, on both an overarching and by-chapter level. This celebrated and varied collection is an indispensable resource for upper-level students, graduate students, and practitioners working in the fields of social work, addictions studies, and the helping professions. FEATURES: - Thoroughly updated chapter-by-chapter content grounded in an anti-oppressive framework with deeper exploration of trauma-informed approaches - Provides an authoritative analysis of the practices and policies that contribute to the construction of the meaning of addiction through a Canadian lens
Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 58
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Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 816
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Author: Library of Congress
Publisher:
ISBN:
Category : Subject catalogs
Languages : en
Pages : 1032
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Book Description
Author: Benjamin E. Blass
Publisher: Academic Press
ISBN: 0128172150
Category : Science
Languages : en
Pages : 738
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Book Description
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator's fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist's early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. - Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property - Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape - Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery - Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309292492
Category : Medical
Languages : en
Pages : 107
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Book Description
Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Author: Canada. Non-medical Use of Drugs Directorate
Publisher:
ISBN:
Category :
Languages : en
Pages :
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