Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

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Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Get Book Here

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Pituitary Adenylate Cyclase-Activating Polypeptide

Pituitary Adenylate Cyclase-Activating Polypeptide PDF Author: Hubert Vaudry
Publisher: Springer Science & Business Media
ISBN: 9781402073069
Category : Medical
Languages : en
Pages : 432

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Book Description
Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Stress Resilience

Stress Resilience PDF Author: Alon Chen
Publisher: Academic Press
ISBN: 0128139838
Category : Psychology
Languages : en
Pages : 390

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Book Description
Stress Resilience: Molecular and Behavioral Aspects presents the first reference available on the full-breadth of cutting-edge research being carried out in this field. It includes a wide range of basic molecular knowledge on the potential associations between resilience phenomenon and biochemical balance, but also focuses on the molecular and cellular mechanisms underlying stress resilience. World-renowned experts provide chapters that cover everything from the neural circuits of resilience, the effects of early-life adversity, and the transgenerational inheritance of resilience. This unique and timely book will be a go-to resource for neuroscientists and biological psychiatrists who want to improve their understanding of the consequences of stress and on how some people are able to avoid it.

Waking the Tiger: Healing Trauma

Waking the Tiger: Healing Trauma PDF Author: Peter A. Levine, Ph.D.
Publisher: North Atlantic Books
ISBN: 9781556432330
Category : Self-Help
Languages : en
Pages : 292

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Book Description
Now in 24 languages. Nature's Lessons in Healing Trauma... Waking the Tiger offers a new and hopeful vision of trauma. It views the human animal as a unique being, endowed with an instinctual capacity. It asks and answers an intriguing question: why are animals in the wild, though threatened routinely, rarely traumatized? By understanding the dynamics that make wild animals virtually immune to traumatic symptoms, the mystery of human trauma is revealed. Waking the Tiger normalizes the symptoms of trauma and the steps needed to heal them. People are often traumatized by seemingly ordinary experiences. The reader is taken on a guided tour of the subtle, yet powerful impulses that govern our responses to overwhelming life events. To do this, it employs a series of exercises that help us focus on bodily sensations. Through heightened awareness of these sensations trauma can be healed.

Stress Management for Life: A Research-Based Experiential Approach

Stress Management for Life: A Research-Based Experiential Approach PDF Author: Michael Olpin
Publisher: Cengage Learning
ISBN: 9781305120594
Category : Sports & Recreation
Languages : en
Pages : 432

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Book Description
Clearly explaining the how to of stress management and prevention, STRESS MANAGEMENT FOR LIFE, 4th Edition emphasizes experiential learning and encourages students to personalize text information through practical applications and a tool box of stress-reducing resources, including activities and online stress-relief audio files. Michael Olpin and Margie Hesson offer more than just a book about stress; they offer students a life-changing experience. Well-researched and engaging, the Fourth Edition empowers students to experience personal wellness by understanding and managing stress, gives stress-related topics a real-life context, and motivates students to manage stress in a way that accommodates their lifestyle, values, and goals. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Good Anxiety

Good Anxiety PDF Author: Wendy Suzuki
Publisher: Simon and Schuster
ISBN: 1982170735
Category : Psychology
Languages : en
Pages : 304

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Book Description
World-renowned neuroscientist and author of Healthy Brain, Happy Life explains how to harness the power of anxiety into unexpected gifts. We are living in the age of anxiety, a situation that often makes us feel as if we are locked into an endless cycle of stress, sleeplessness, and worry. But what if we had a way to leverage our anxiety to help us solve problems and fortify our wellbeing? What if, instead of seeing anxiety as a curse, we could recognize it for the unique gift that it is? Dr. Wendy Suzuki has discovered a paradigm-shifting truth about anxiety: yes, it is uncomfortable, but it is also essential for our survival. In fact, anxiety is a key component of our ability to live optimally. Every emotion we experience has an evolutionary purpose, and anxiety is designed to draw our attention to vulnerability. If we simply approach it as something to avoid, get rid of, or dampen, we actually miss an opportunity to improve our lives. Listening to our anxieties from a place of curiosity, and without fear, can actually guide us onto a path that leads to joy. Drawing on her own intimate struggles and based on cutting-edge research, Dr. Suzuki has developed an inspiring guidebook for managing unwarranted anxiety and turning it into a powerful asset. In the tradition of Quiet and Thinking, Fast and Slow, Good Anxiety has the power to permanently change how we understand anxiety and, more importantly, how we can use it to improve our lives for the better.

Recognition and Alleviation of Distress in Laboratory Animals

Recognition and Alleviation of Distress in Laboratory Animals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309108179
Category : Science
Languages : en
Pages : 137

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Book Description
Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. This new book from the Institute for Laboratory Animal Research (ILAR) at the National Research Council, Recognition and Alleviation of Distress in Laboratory Animals, focuses on the stress and distress which is experienced by animals when used in laboratory research. This book aims to educate laboratory animal veterinarians; students, researchers, and investigators; animal care staff, as well as animal welfare officers on the current scientific and ethical issues associated with stress and distress in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines. Recognition and Alleviation of Distress in Laboratory Animals focuses specifically on the scientific understanding of the causes and the functions of stress and distress, the transformation of stress to distress, and the identification of principles for the recognition and alleviation of distress. This book discusses the role of humane endpoints in situations of distress and principles for the minimization of distress in laboratory animals. It also identifies areas in which further scientific investigation is needed to improve laboratory animal welfare in order to adhere to scientific and ethical principles that promote humane care and practice.

Emotional Inflammation

Emotional Inflammation PDF Author: Lise Van Susteren, MD
Publisher: Sounds True
ISBN: 1683644565
Category : Self-Help
Languages : en
Pages : 0

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Book Description
A Powerful Guide for Overcoming the Emotional Challenges of Our Turbulent Times. A rising number of people today are troubled by a phenomenon for which they don’t know there’s a name. This condition is called emotional inflammation—a state not unlike post-traumatic stress disorder, but one that stems from simply living in today’s anxious, overwhelming, and tumultuous world. If you’ve suffered from sleep problems, hyperreactivity, persistent grief, or inescapable worry about the future—especially triggered by the nonstop news cycle—then you’re probably dealing with emotional inflammation. The good news is: there’s something you can do about it. With Emotional Inflammation, general and forensic psychiatrist Dr. Lise Van Susteren joins writer Stacey Colino to present a breakthrough guide to help you become grounded and resilient in these turbulent times. You’ll begin by determining your “reactor type” to better understand how your body and mind respond to stress overload. Then you’ll learn the vital steps of the powerful RESTORE program for recovering inner balance, personal effectiveness, and joy in your life: • Recognize Your Feelings: how to identify, unpack, and learn from difficult emotions • Evaluate Your Triggers: pinpoint what sets you off and how you can moderate your reactivity • Steady Your Body’s Natural Rhythms: keys for restoring your natural, healthy internal equilibrium • Think Yourself into a Safe Space: work with your mind to remain flexible, thoughtful, and adaptable • Obey Your Body: essential self-care practices for diet, exercise, stress management, and more • Reclaim the Gifts of Nature: revitalize your healing connection to the natural world and its awe-inspiring benefits • Exercise Your Power: become an “upstander” who takes effective action from a place of compassion, hope, and love Completing the basics of this method, the authors share key insights on how to personalize RESTORE to fit into your life based on which of the four reactor types you identify with—Nervous, Revved, Molten, or Retreating. You can’t always control the crises and catastrophes that are swirling around you. But that does not mean you’re powerless against the status quo—nor do you need to be at the mercy of the physiological, psychological, and spiritual stress responses inside you. With Emotional Inflammation, you now have an invaluable guide to help you cope with the challenges of a turbulent world, calm your body and mind, and reclaim a sense of peace, purpose, and connection to others.

Handbook of Human Stress and Immunity

Handbook of Human Stress and Immunity PDF Author: Ronald Glaser
Publisher: Academic Press
ISBN: 1483295125
Category : Medical
Languages : en
Pages : 436

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Book Description
In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.

Musculoskeletal Disorders and the Workplace

Musculoskeletal Disorders and the Workplace PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309132991
Category : Business & Economics
Languages : en
Pages : 510

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Book Description
Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.