Construction of a CDNA Library as a Tool for Analysis of Differential Gene Expression in Hybrids Between Species of Spadefoot Toads PDF Download
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Author: Kelly R. Haisley
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Kelly R. Haisley
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 31
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Book Description
Sequencing of full-insert clones from full-length cDNA libraries from both Xenopus laevis and Xenopus tropicalis has been ongoing as part of the Xenopus Gene Collection initiative. Here we present an analysis of 10967 clones (8049 from X. laevis and 2918 from X. tropicalis). The clone set contains 2013 orthologs between X. laevis and X. tropicalis as well as 1795 paralog pairs within X. laevis. 1199 are in-paralogs, believed to have resulted from an allotetraploidization event approximately 30 million years ago, and the remaining 546 are likely out-paralogs that have resulted from more ancient gene duplications, prior to the divergence between the two species. We do not detect any evidence for positive selection by the Yang and Nielsen maximum likelihood method of approximating d{sub N}/d{sub S}. However, d{sub N}/d{sub S} for X. laevis in-paralogs is elevated relative to X. tropicalis orthologs. This difference is highly significant, and indicates an overall relaxation of selective pressures on duplicated gene pairs. Within both groups of paralogs, we found evidence of subfunctionalization, manifested as differential expression of paralogous genes among tissues, as measured by EST information from public resources. We have observed, as expected, a higher instance of subfunctionalization in out-paralogs relative to in-paralogs.
Author: Supratim Choudhuri
Publisher: Elsevier
ISBN: 0124105106
Category : Science
Languages : en
Pages : 238
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Book Description
Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration
Author: Deepthi Rajagopalan
Publisher:
ISBN: 9780494929933
Category :
Languages : en
Pages :
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Author: Thomas Flatt
Publisher: OUP Oxford
ISBN: 0191621021
Category : Science
Languages : en
Pages : 506
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Book Description
Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction, and survival and by investigating the trade-offs that constrain the evolution of these traits. Although life history theory has made enormous progress in explaining the diversity of life history strategies among species, it traditionally ignores the underlying proximate mechanisms. This novel book argues that many fundamental problems in life history evolution, including the nature of trade-offs, can only be fully resolved if we begin to integrate information on developmental, physiological, and genetic mechanisms into the classical life history framework. Each chapter is written by an established or up-and-coming leader in their respective field; they not only represent the state of the art but also offer fresh perspectives for future research. The text is divided into 7 sections that cover basic concepts (Part 1), the mechanisms that affect different parts of the life cycle (growth, development, and maturation; reproduction; and aging and somatic maintenance) (Parts 2-4), life history plasticity (Part 5), life history integration and trade-offs (Part 6), and concludes with a synthesis chapter written by a prominent leader in the field and an editorial postscript (Part 7).
Author: Brenda Walpole
Publisher: Cambridge University Press
ISBN: 0521171784
Category : Juvenile Nonfiction
Languages : en
Pages : 609
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Book Description
This text offers an in-depth analysis of all topics covered in the IB syllabus, preparing students with the skills needed to succeed in the examination. Features include: clearly stated learning objectives at the start of each section; quick questions throughout each chapter and accessible language for students at all levels.
Author: Stephen A. Wainwright
Publisher: Princeton University Press
ISBN: 9780691083087
Category : Science
Languages : en
Pages : 444
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Book Description
This book deals with an interface between mechanical engineering and biology. It reviews biological structural materials and systems and their mechanically important features and demonstrates that function at any particular level of biological integration is permitted and controlled by structure at lower levels of integration.
Author: G. Czihak
Publisher: Springer Science & Business Media
ISBN: 3642659640
Category : Science
Languages : en
Pages : 719
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Book Description
Sea urchin eggs are objects of wonder for the student who sees them for the first time under the microscope. The formation of the fertil ization membrane after insemination, the beauty of mitotic cleavage, the elegant swimming of embryos, remain an esthetic pleasure even for the eyes of seasoned investigators. But sea urchin eggs have other, more practical, advantages: they lend themselves to surgical operation without difficulty and they heal perfectly; they can be obtained in very large amounts and represent thus an extremely favorable material for biochemists and molecular embryologists. It is not surprising that, in view of these exceptional advantages, sea urchin eggs have attracted the interest of innumerable biologists since O. HERTWIG discovered the fusion of the pronuclei (amphimixy), in Paracentrotus lividus, almost a century ago. The purpose of the present book is to present, in a complete and orderly fashion, the enormous amount of information which has been gathered, in the course of a hun dred years of sea urchin embryology. JOSEPH NEEDHAM, in 1930, was still able to present all that was known, at that time, on the biochemistry of all possible species of developing eggs and embryos in his famous "Chemical Embryology" (Cambridge University Press) . It would no longer be possible for one man to write a modern version of what was a "Bible" for the young embryologists of forty years ago.
Author: Bernard Fried
Publisher: Springer Science & Business Media
ISBN: 9780792361565
Category : Medical
Languages : en
Pages : 294
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Book Description
Echinostomes are ubiquitous intestinal flatworm parasites of vertebrates, and are important in human and veterinary medicine and wildlife diseases. They are also very good models for biology experiments because they are easy and inexpensive to maintain in adult and larval worm stages, and of course are unlikely to draw the attention of animal rights advocates. They have been used for decades for research, but practical information on such use has not been compiled in a single reference before. They have been used in experiments in excystation and in-vitro cultivation, larval and adult parasite-host relationships, reproductive behavior, various aspects of host-parasite recognition and interactions, and other concerns at all levels from molecular to organismic. The topics include biology; systematics; maintenance, cultivation, and excystation; behavioral biology; reproductive physiology and behavior; physiology and biochemistry; and immunobiology and immunodiagnosis.
Author: D. J. Galas
Publisher: Caister Academic Press Limited
ISBN: 9780954246426
Category : Science
Languages : en
Pages : 0
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Book Description
Genomics is a new and fast expanding area of biology encompassing high throughput or large scale experimentation at the whole genome level, and the organization, analysis and interpretation of the huge amount of data emerging from genome projects. Major new technologies have evolved recently that enable experimentation at the whole genome level, and more novel technologies are currently being developed. This volume describes in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. Written by experts in the field, this concise yet informative volume covers all aspects of technology pertaining to genomic studies. It is an essential book for anyone involved in genomic science.
