Computational Methods in Cardiac Electrophysiology

Computational Methods in Cardiac Electrophysiology PDF Author: Matthijs Cluitmans
Publisher: Frontiers Media SA
ISBN: 2832529259
Category : Science
Languages : en
Pages : 229

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Book Description

Computational Methods in Cardiac Electrophysiology

Computational Methods in Cardiac Electrophysiology PDF Author: Matthijs Cluitmans
Publisher: Frontiers Media SA
ISBN: 2832529259
Category : Science
Languages : en
Pages : 229

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Book Description


Cardiac Electrophysiology Methods and Models

Cardiac Electrophysiology Methods and Models PDF Author: Daniel C. Sigg
Publisher: Springer Science & Business Media
ISBN: 1441966587
Category : Medical
Languages : en
Pages : 490

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Book Description
Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Computational Cardiology

Computational Cardiology PDF Author: Frank B. Sachse
Publisher: Springer
ISBN: 3540259260
Category : Medical
Languages : en
Pages : 364

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Book Description
This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Mathematical Cardiac Electrophysiology

Mathematical Cardiac Electrophysiology PDF Author: Piero Colli Franzone
Publisher: Springer
ISBN: 3319048015
Category : Mathematics
Languages : en
Pages : 397

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Book Description
This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Introduction to Computational Cardiology

Introduction to Computational Cardiology PDF Author: Boris Ja. Kogan
Publisher: Springer Science & Business Media
ISBN: 0387766863
Category : Computers
Languages : en
Pages : 236

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Book Description
Introduction to Computational Cardiology provides a comprehensive, in-depth treatment of the fundamental concepts and research challenges involved in the mathematical modeling and computer simulation of dynamical processes in the heart, under normal and pathological conditions. About this textbook: - Presents descriptions of models used in both biology and medicine for discovering the mechanisms of heart function and dysfunction on several physiological scales across different species. - Provides several examples throughout the textbook and exercises at the end which facilitate understanding of basic concepts and introduces, for implementation, treated problems to parallel supercomputers. Introduction to Computational Cardiology serves as a secondary textbook or reference book for advanced-level students in computer science, electrical engineering, biomedical engineering, and cardiac electrophysiology. It is also suitable for researchers employing mathematical modeling and computer simulations of biomedical problems.

Functional Imaging and Modeling of the Heart

Functional Imaging and Modeling of the Heart PDF Author: Frank B. Sachse
Publisher: Springer
ISBN: 3540729070
Category : Computers
Languages : en
Pages : 488

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Book Description
This book constitutes the refereed proceedings of the 4th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2007, held in Salt Lake City, UT, USA in June 2007. The contributions describe both experimental and computational studies and cover topics such as imaging and image analysis, cardiac electrophysiology, electro- and magnetocardiography, cardiac mechanics and clinical application, imaging and anatomical modeling.

Exploring Mechanisms of Cardiac Rhythm Disturbances Using Novel Computational Methods: Prediction, Classification, and Therapy

Exploring Mechanisms of Cardiac Rhythm Disturbances Using Novel Computational Methods: Prediction, Classification, and Therapy PDF Author: Xin Li
Publisher: Frontiers Media SA
ISBN: 2832517587
Category : Science
Languages : en
Pages : 232

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Book Description


Computational Cardiology: Modelling of Anatomy, Electrophysiology and Mechanics

Computational Cardiology: Modelling of Anatomy, Electrophysiology and Mechanics PDF Author: Frank B. Sachse
Publisher:
ISBN: 9781280307362
Category : Medical
Languages : en
Pages : 322

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Book Description
This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way.First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics.This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Computational Methods in Systems Biology

Computational Methods in Systems Biology PDF Author: Jun Pang
Publisher: Springer Nature
ISBN: 3031426975
Category :
Languages : en
Pages : 287

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Book Description


Computing the Electrical Activity in the Heart

Computing the Electrical Activity in the Heart PDF Author: Joakim Sundnes
Publisher: Springer Science & Business Media
ISBN: 3540334378
Category : Computers
Languages : en
Pages : 323

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Book Description
This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. It gives an introduction to the most important models, followed by a detailed description of numerical techniques. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers. The results presented in the book will be of particular interest to researchers in bioengineering and computational biology.